Researchers successfully used a protein called parapinopsin to turn off brain circuits. This protein is found in lamprey – an ancient lineage of jawless fish similar to eel. Researchers said the ability to inhibit neurons could eventually lead to turning off mood disorders and unwanted behaviors like depression and addiction.
Using a mouse model, researchers discover pivotal role of cholesterol in chronic pain often caused by chemotherapy, and propose novel therapy.
Programs that provide ongoing support to patients with painful conditions and complex medication regimens may also help them avoid using potentially risky opioid pain medications, or reduce the amount they use, a new study finds.
By discovering a potential new cellular mechanism for migraines, researchers may have also found a new way to treat chronic migraine. Amynah Pradhan, associate professor of psychiatry at the University of Illinois Chicago, is the senior author of the study, whose goal was to identify a new mechanism of chronic migraine, and propose a cellular pathway for migraine therapies.
A recent study from the University of Helsinki monitors the breakthrough progresses in the development of microneedles for immunotherapy and discusses the challenges regarding their production.
A new study, presented today at the AATS 101st Annual Meeting, shows significant reduction in post-operative use of Schedule II opioids for pain management following robotic surgery.
When they go to the dentist, patients might not think that the pain prescription they receive could put them or their family at risk of an opioid overdose. But a new study shows that overdose rates were two and a half times higher among patients who filled a prescription for an opioid medication after a dental procedure.
The American College of Radiology® (ACR®) today released an update to its ACR Appropriateness Criteria® (ACR AC), which includes 211 diagnostic imaging and interventional radiology topics with more than 1,000 clinical variants covering approximately 1,900 clinical scenarios.
Researchers find that opioids are not necessary for managing post-knee surgery pain.
Chronic pain is among the most common chronic conditions in the United States, but estimates of its prevalence and impact vary widely.
Policies designed to prevent the misuse of opioids may have the unintended side effect of limiting access to the pain-relieving drugs by terminally ill patients nearing the end of their life, new research led by the Oregon State University College of Pharmacy suggests.
The Chiropractic Coverage Modernization Act (H.R. 2654), introduced April 19 in the U.S. House of Representatives, would increase Medicare coverage of services provided by doctors of chiropractic within the full extent of their state licensure, enabling chiropractic patients to conveniently and safely access needed care.
The Chiropractic Coverage Modernization Act (H.R. 2654), introduced April 19 in the U.S. House of Representatives, would increase Medicare coverage of services provided by doctors of chiropractic within the full extent of their state licensure, enabling chiropractic patients to conveniently and safely access needed care.
COVID-19 has been associated with increases in opioid overdose deaths, which may be in part because the pandemic limited access to buprenorphine, a treatment used for opioid dependency, according to a new study led by Princeton University researchers.
Financial stress can have an immediate impact on well-being, but can it lead to physical pain nearly 30 years later? The answer is yes, according to new research from University of Georgia scientists.
Benefits 'Much Greater Than Anticipated' in Initial Randomized Trial
When Maria Reynoso developed low-back pain, she thought it was not serious and would quickly go away. She was an active gym member who had recently retired after 33 years as a second-grade schoolteacher and was always available to help her aging parents.
Ontario doctors are still hesitant to prescribe medical cannabis to patients suffering long-term pain 20 years after it was first introduced, says a new study carried out at McMaster University.
The American Society of Regional Anesthesia and Pain Medicine has joined 10 other pain societies in issuing a practice advisory on the use of gadolinium-based contrast agents. This off-label use is an alternative option for patients with hypersensitivity to the traditional contrast medium.
Researchers report in Science Advances that they have uncovered a new function for odontoblasts, the cells that form dentin, the shell beneath the tooth's enamel that encases the soft dental pulp containing nerves and blood vessels.
A Penn Medicine new study of how text messaging could inform opioid prescribing practices showed that 60 percent of opioids are left over after orthopaedic and urologic procedures
We all feel physical pain in different ways, but people with nerve injuries often have a dysfunctional pain suppression system, making them particularly prone to discomfort.
This discovery from UNC School of Medicine scientists, published in the journal Neuron, could help the scientific community devise better pain management strategies, particularly for women, who are disproportionally affected by pain throughout their lifespans.
Many office-based employees find themselves still working from home a full year after the COVID-19 (coronavirus) pandemic forced work as we knew it to change dramatically.
Millions of people are administered general anesthesia each year in the United States alone, but it’s not always easy to tell whether they are actually unconscious. A small proportion of those patients regain some awareness during medical procedures, but a new study of the brain activity that represents consciousness could prevent that potential trauma.
A team of Chula doctoral students has created a smart “DynaSeat” to adjust sitting behavior to prevent neck pain and promote fast recovery after office syndrome.
A gene therapy for chronic pain could offer a safer, non-addictive alternative to opioids. Researchers at the University of California San Diego developed the new therapy, which works by temporarily repressing a gene involved in sensing pain. It increased pain tolerance in mice, lowered their sensitivity to pain and provided months of pain relief without causing numbness.
A new Loyola Medicine study found that reducing the standard dose of IV-administered ketamine in half is as effective as the larger, standard dose in reducing pain in adults.
For the first time, an app has been shown to reduce key symptoms of chronic pain. A UNH-led study evaluated the impact of Manage My Pain(MMP), a digital health solution on chronic pain patients.
Inflammation is a hallmark of chronic pain, and scientists at the UNC School of Medicine have discovered that anti-inflammatory cells called MRC1+ macrophages are dysfunctional in an animal model of neuropathic pain.
During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every other Wednesday.
Using cannabis for relief from migraine headache may be associated with developing “rebound” headache, or medication overuse headache, which occurs when pain medication is overused by patients who have an underlying primary headache disorder such as migraine, according to a preliminary study released today March 1, 2021, that will be presented at the American Academy of Neurology’s 73rd Annual Meeting being held virtually April 17 to 22, 2021.
A prescribing guideline tailored to patients’ specific needs reduced the number of opioid pills prescribed after major surgery.
The American Society of Anesthesiologists (ASA) hosted a virtual pain summit on February 20, 2021 with 14 medical specialty societies to discuss acute surgical pain principles that will serve as the basis for a multi-society acute pain resource. The first-of-its-kind event brought together a group of representing the major surgical stakeholders in acute pain management with the goal of reaching consensus on important principles regarding the treatment of perioperative pain. These principles will be developed into a guiding resource for clinicians and all members of the surgical care team in 2021.
Researchers reporting in ACS’ Nano Letters have developed magnesium-based micromotors propelled by hydrogen bubbles, which improved rheumatoid arthritis symptoms when injected into the joints of rats.
DALLAS – Feb. 22, 2021 – Three decades-old antibiotics administered together can block a type of pain triggered by nerve damage in an animal model, UT Southwestern researchers report. The finding, published online today in PNAS, could offer an alternative to opioid-based painkillers, addictive prescription medications that are responsible for an epidemic of abuse in the U.S.
In a statewide study of adults over 60 with osteoarthritis, researchers found that effective treatment for insomnia can be delivered in a few short phone calls.
The Psychedelics and Health Research Initiative at UC San Diego has received a $1.3 million grant from the Steven & Alexandra Cohen Foundation to fund a clinical trial investigating the therapeutic potential of psilocybin in treating phantom limb pain.
Among the orthopaedic surgery patients in a study using text messaging to monitor opioid use, 61 percent of their tablets were found to be left over
A team of researchers from the Case Western Reserve University School of Medicine, Case School of Engineering and Louis Stokes Cleveland VA Medical Center is developing a blood-test device as an early warning system to help prevent pressure injuries.
According to some estimates, chronic pain affects up to 40% of Americans, and treating it frustrates both clinicians and patients––a frustration that's often compounded by a hesitation to prescribe opioids for pain.
Eating a more pro-inflammatory diet was associated with higher incidence of low back pain, according to a new study presented this week at the Association of Academic Physiatrists Annual Meeting.
The increased precision and visibility offered by robotic surgery has given gynecological surgeons a better understanding of pelvic nerve inflammation as a cause of pelvic pain and pelvic floor dysfunction.
Researchers at Flinders University are working to remedy this situation by identifying what triggers this chronic pain in the female reproductive tract.
The American Chiropractic Association (ACA) has endorsed five backpacks from Vera Bradley, a leading American bag and luggage company and iconic lifestyle brand. The brand’s Campus Backpack®, XL Campus Backpack®, XL Journey Backpack®, ReActive Grand Backpack® and ReActive XL Backpack® were approved following an evaluation by a review board of ACA chiropractors, who acknowledged both their smart functionality as well as body-healthy features.
Researchers identified spinal cord neurons responsible for an itchy sensation after an epidural morphine injection and found a drug that may fix the problem without reducing morphine’s pain-killing effects.
A study published today in the New England Journal of Medicine provides the most definitive evidence to date that, of the two drugs recommended for light sedation of patients receiving mechanical ventilation in the ICU, one is as effective and safe as the other.
Irvine, Calif., Feb. 1, 2021 — Researchers from the University of California, Irvine and the University of Minnesota have found that an enriched diet and companionship can reduce pain in mice with sickle cell disease by increasing serotonin. They also discovered that duloxetine, an antidepressant that boosts serotonin levels, could be an alternative to opioids in treating chronic pain.
Researchers at Washington University School of Medicine in St. Louis have engineered cartilage cells to release an anti-inflammatory drug in response to stresses such cells undergo when they are compressed during weight bearing and movement.
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