Estima-se que uma a cada dez pessoas ao redor do mundo tem doença renal crônica, mas a maioria delas não sabe disso. A falta de conhecimento é particularmente preocupante porque as pessoas com doença renal crônica que se infectarem com COVID-19 têm maior risco de apresentar a forma grave da doença.
قد لا يشعر الأشخاص المصابون بأمراض الكلى المزمنة بالمرض أو يلاحظون الأعراض. لكنها مصدر قلق صحي عالمي، مع عدد وفيات يُقدَّر بنحو 1.1 مليون في جميع أنحاء العالم.
Se calcula que 1 de cada 10 personas en el mundo sufre de insuficiencia renal crónica, pero la mayoría de ellas no lo saben. Ese desconocimiento es particularmente preocupante porque cuando alguien con insuficiencia renal crónica se infecta con la COVID-19, tiene mucho más riesgo de enfermar gravemente.
DALLAS – March 8, 2021 – A study led by UT Southwestern and Children’s Health researchers defines parameters for the number of white blood cells that must be present in children’s urine at different concentrations to suggest a urinary tract infection (UTI). The findings, published recently in Pediatrics, could help speed treatment of this common condition and prevent potentially lifelong complications.
An estimated 1 in 10 people worldwide have chronic kidney disease, but most of them don't know it. That lack of awareness is especially concerning because people with Chronic kidney disease who are infected with COVID-19 are at higher risk for serious illness.
Nearly 74,000 people will be diagnosed with kidney cancer in the United States this year according to the American Cancer Society.
Overweight children who were exposed to lead in utero and during their first weeks of life have the potential for poorer kidney function in adulthood, according to an Icahn School of Medicine at Mount Sinai study published in Environment International in March.
• Adding measures of kidney function to traditional measures of cardiovascular health could help clinicians predict an individual’s risk of developing cardiovascular disease.
The March 2021 issue of Toxicological Sciences includes exciting toxicology research in biotransformation, toxicokinetics, and pharmacokinetics; genetic and epigenetic toxicology; neurotoxicology; and more.
During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every other Wednesday.
妙佑医疗国际(Mayo Clinic) 的研究人员在《国际肾脏报告》(Kidney International Reports)中发表的一项研究表明，免疫检查点抑制剂可能会对一些患者产生负面影响，包括导致名为“间质性肾炎”的急性肾炎。免疫检查点抑制剂治疗癌症的方法是刺激免疫系统，使其攻击癌细胞。
Molecules called microRNAs (miRNAs) that are measurable in urine have been identified by researchers at Mount Sinai as predictors of both heart and kidney health in children without disease. The epidemiological study of Mexican children was published in February in the journal Epigenomics.
• Patients with kidney failure associated with sickle cell disease benefit from kidney transplants, but they’re less likely than other patients to receive them.
Washington, DC (February 25, 2021) —The American Society of Nephrology (ASN) is spearheading efforts to secure direct federal allocation of COVID-19 vaccines to dialysis patients and frontline dialysis workers. This allocation would improve access for a vulnerable patient population, more than half of whom are Black, Hispanic, Asian, Native American, and Native Hawaiian or other Pacific Islanders (NHPIs).
Long thought a vestigial part of human cells, new genetic analysis of the primary cilium shows that it may be tied to common conditions like diabetes and kidney failure
A web-based tool developed by Jefferson researchers predicts individualized risk for stroke, other grave post-surgical complications
An artificial intelligence-enabled in vitro diagnostics company and the University of Utah today announced a partnership to improve kidney health and reduce the risk of kidney failure for large scale populations in the earliest stages of kidney disease.
Researchers have discovered a blood biomarker that predicts kidney transplant rejection with a lead time of about eight months, which could give doctors an opportunity to intervene and prevent permanent damage, potentially using an existing medication.
UCLA researchers found that patients’ decision-making about how and when to seek treatment for kidney stones was driven by logistical barriers and patients’ reluctance to risk exposure to COVID-19 in health care facilities.
• Racial disparities in access to kidney transplantation persist in the United States. New research indicates that registering Black patients on the kidney transplant waitlist at a slightly higher level of kidney function compared with white patients might lessen racial inequality in patients’ wait time prior to kidney failure onset, and ultimately improve racial equity in access to kidney transplantation.
A recommendation for more intensive blood pressure management from an influential global nonprofit that publishes clinical practice guidelines in kidney disease could, if followed, benefit nearly 25 million Americans.
Around 80% of the UK population is currently infected with human cytomegalovirus (HCMV) and in developing countries this can be as high as 95%.
• Veterans who receive all of their post–kidney transplant care within the Veterans Health Administration (VA) have a lower risk of death than those who receive care outside the VA through Medicare coverage, according to a recent study.
The Cardio-Renal Pediatric Dialysis Emergency Machine (CARPEDIEM) is a new system for patients with acute kidney injury or kidney failure requiring dialysis. This ground-breaking technology is intended to provide continuous renal replacement therapy (CRRT) to patients weighing between 5 and 20 pounds.
وجدت دراسة أجراها باحثو مايو كلينك ونُشرت في تقارير "كدني إنترناشونال" أن مثبطات نقاط التفتيش المناعية قد يكون لها عواقب سلبية على بعض المرضى، منها: التهاب الكُلى الحاد، المعروف باسم التهاب الكلية الخِلالي. وتُستخدم مثبطات نقاط التفتيش المناعية لعلاج السرطان عن طريق تحفيز جهاز المناعة لمهاجمة الخلايا السرطانية.
Un estudio dirigido por investigadores de Mayo Clinic y publicado en Kidney International Reports (Informes Internacionales sobre el Riñón) descubrió que los inhibidores de los puntos de control inmunitario pueden tener consecuencias negativas en algunos pacientes, incluida una inflamación aguda del riñón conocida como nefritis intersticial.
Patients with advanced kidney cancer, who received a targeted drug combined with a checkpoint-blocker immunotherapy agent had longer survival than patients treated with the standard targeted drug, said an investigator from Dana-Farber Cancer Institute, reporting results from a phase 3 clinical trial.
• Despite wide recognition, policy reforms, and extensive research to address barriers in patients’ access to kidney transplantation, investigators found no improvement in rates of wait list placement and transplantation over 2 decades. • Moreover, rates among vulnerable populations are especially low.
People undergoing long-term dialysis are almost 4 times more likely to die from COVID-19 and should be prioritized for vaccination, found a new Ontario study published in CMAJ (Canadian Medical Association Journal).
— The American Society of Nephrology (ASN) re- affirms its support for the Organ Procurement Organizations (OPOs) Conditions for Coverage final rule issued on November 20, 2020. The society calls for the Biden-Harris administration to implement this final policy as expediently as possible. By bringing objective and verifiable standards to assess the performance of OPOs, this final rule will increase the number of organs available for transplant and reduce racial inequity in the U.S. transplant system.
A study by Mayo Clinic researchers published in Kidney International Reports finds that immune checkpoint inhibitors, may have negative consequences in some patients, including acute kidney inflammation, known as interstitial nephritis. Immune checkpoint inhibitors are used to treat cancer by stimulating the immune system to attack cancerous cells.
Rheoscan (model: Rheoscan-And300, Rheoscan-D300) system is an in vitro diagnostic device that tests the erythrocyte deformability, aggregation, and critical shear stress used as a POC device.
• Race and social determinants of health were associated with the likelihood of undergoing kidney transplantation among US adults with kidney failure. • Interventions that target social determinants of health may improve access to kidney transplantation.
New research suggests the toxic effects of nicotine on the kidneys’ filtering function are partly responsible for the progression of diabetes-related kidney disease in people who smoke. The study is published ahead of print in the American Journal of Physiology-Renal Physiology.
On December 9, 2020, Gianna Graw saved four lives and became the first patient to make a “good samaritan” kidney donation through Hackensack University Medical Center’s partnership with National Kidney Registry (NKR), an organization that facilitates living donor kidney transplants.
UC San Diego Health’s lung, heart, kidney and liver transplant programs rank at the top nationally in the latest biannual Scientific Registry of Transplant Recipients (SRTR) report. Innovative treatment and multi-disciplinary care contribute to the high rankings for one-year survival outcomes.
The American Society of Nephrology (ASN) welcomes Susan E. Quaggin, MD, FRCP(C), FASN, as ASN President, effective January 1, 2021. Dr. Quaggin succeeds Anupam Agarwal, MD, FASN.
• In a survey of adults with kidney failure who were receiving dialysis, most owned mobile devices and had intermediate or advanced mobile health proficiency. • The main reasons for using mobile health were for making appointments, communicating with healthcare personnel, and obtaining laboratory results.
• An estimated 375 adult kidney transplant recipients lose their transplant every year due to a lack of coverage of immunosuppressive medications after the prior 36-month Medicare coverage period. • Congress passes ASN priority legislation to extend immunosuppressive drug coverage for kidney transplant patients. • The bipartisan bill is expected to save Medicare $400,000,000 over 10 years by averting the return of transplant patients to dialysis.
A virtual telehealth platform is allowing a surgery program to evaluate and wait-list patients for kidney transplantation.
• Exposure to higher amounts of fine particulate air pollution was associated with a greater likelihood of having chronic kidney disease. • This link was stronger in urban areas, males, younger adults, and adults without comorbid diseases.
A joint statement from the National Kidney Foundation and the American Society of Nephrology December 17, 2020
Renal blood flow changes throughout the day in tandem with the body’s circadian clock, with increasing flow during daytime hours and decreasing flow in the evening and into the night.
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