For people with psoriasis, a chronic skin condition, taking good care of their skin can alleviate some of the discomfort that may be experienced, such as itching, cracking and bleeding of the skin.
Many drugs such as agents for cancer or autoimmune diseases have nasty side effects because while they kill disease-causing cells, they also affect healthy cells. Now a new study has demonstrated a technique for developing more targeted drugs, by using molecular “robots” to hone in on more specific populations of cells.
Baylor Research Institute, the research arm of Baylor Health Care System, announced that it has signed an agreement with Novartis to non-exclusively license Baylor’s patents pertaining to the treatment of Systemic Onset Juvenile Idiopathic Arthritis (SJIA, or SOJIA) using interleukin-1 beta antagonists.
Children who suffer from arthritis could one day receive more targeted treatment thanks to potential markers for the severity of the disorder discovered by researchers at the University of Adelaide and Women's and Children's Hospital.
Many researchers believe when the microbiome is unbalanced, it predisposes us to numerous autoimmune diseases. Chief Medical Officer of Coronado Biosciences, Karin Hehenberger, believes the theory about microbiota is related to the “hygiene hypothesis”—the notion that there is a direct link between elevated rates of autoimmune diseases and Western society’s obsession to establish germ-free environments. One approach comes in the form of a treatment involving Trichuris suis ova (TSO)—pig whipworm eggs.
Two new studies by researchers at Hospital for Special Surgery have shed light on joint replacement outcomes in patients with rheumatoid arthritis (RA).
The painful rheumatic condition gout is often associated with the big toe, but it turns out that patients at highest risk of further flare-ups are those whose gout first involved other joints, such as a knee or elbow, Mayo Clinic has found. The study is among several that Mayo researchers are presenting in Madrid at the European League Against Rheumatism’s annual meeting.
Whether damaged by injury, disease or age, your body can’t create new bone, but maybe science can. Researchers at North Dakota State University, Fargo, are making strides in tissue engineering, designing scaffolds that may lead to ways to regenerate bone. Published in the Journal of Biomedical Materials Research Part A, the research of Dr. Kalpana Katti, Dr. Dinesh Katti and graduate student Avinash Ambre includes a novel method that uses nanosized clays to make scaffolds to mineralize bone minerals such as hydroxyapatite.
Strength training may help older individuals manage knee pain associated with knee osteoarthritis. A new study at Wake Forest University is developing a surgery-free and effective option to treat knee pain and loss of mobility associated with knee osteoarthritis.
In a series of lab experiments designed to unravel the workings of a key enzyme widely considered a possible trigger of rheumatoid arthritis, researchers at Johns Hopkins have found that in the most severe cases of the disease, the immune system makes a unique subset of antibodies that have a disease-promoting role.
An upcoming symposium will offer highlights of the 150-year history of Hospital for Special Surgery and at the same time provide a fascinating look at the evolution of medicine from the “Dark Ages” of the Civil War period to modern medicine as we know it today.
Hospital for Special Surgery in New York City has received a $5.6 million grant from The Tow Foundation to establish the Hospital for Special Surgery Genomics Center. The new center will apply genomic approaches to study two autoimmune diseases, rheumatoid arthritis and systemic lupus erythematosus, with the aim of developing more effective therapies.
An international, multi-center study led by researchers at Hospital for Special Surgery has found that total knee replacements in younger patients with juvenile arthritis last at least 10 years in 92 percent of cases. More than 75 percent of the implants lasted 20 years or more.
Workers with rheumatoid arthritis (RA) incur increased direct and indirect health-related costs, reports a study in the March Journal of Occupational and Environmental Medicine, official publication of the American College of Occupational and Environmental Medicine (ACOEM).
A University of Iowa study of women's feet during and after pregnancy shows that arch height and arch rigidity decrease significantly from early pregnancy to five months after childbirth, causing corresponding increases in foot length that appear to be permanent.
Clinicians looking to enhance their ability to diagnose and treat patients with psoriasis and psoriatic arthritis have a new tool available with the introduction of the American Academy of Dermatology’s (Academy) mobile app of the Academy’s evidence-based clinical guidelines for these skin and joint conditions.
OrthoSensor technology provides real-time visual data during surgery, enhancing surgical skills and enabling consistent joint positioning, longevity and long-term outcomes.
March is National Autoimmune Disease Awareness Month 2013. To mark the annual event, the American Autoimmune Related Diseases Association Inc. (AARDA) is encouraging the national and local media around the country to report stories on autoimmune diseases (AD) and autoimmunity as a category of disease.
Researchers at Hospital for Special Surgery have identified a potential new target for drugs to treat patients with rheumatoid arthritis. Efforts to develop drugs that hone in on this new target are underway.
In one of the first genome-wide studies to hunt for both genes and their regulatory “tags” in patients suffering from a common disease, researchers have found a clear role for the tags in mediating genetic risk for rheumatoid arthritis (RA). The scientists say they were able to spot tagged DNA sequences that may be important for the development of RA.
People suffering from chronic inflammatory conditions, such as rheumatoid arthritis, inflammatory bowel disease and asthma — in which psychological stress plays a major role — may benefit from mindfulness meditation techniques, according to a study by University of Wisconsin-Madison neuroscientists with the Center for Investigating Healthy Minds at the Waisman Center.
Only twenty percent of people will lose weight and keep it off this year, despite research that two-thirds of Americans admit to being on a diet. Here are the top four reasons where dieters go wrong, according to Jessica Bartfield, MD, Loyola Center for Metabolic Surgery & Bariatric Care.
Researchers at Rush University Medical Center, in collaboration with researchers at Northwestern University, have identified a molecular mechanism central to the development of osteoarthritis (OA) pain, a finding that could have major implications for future treatment of this often-debilitating condition.
More than 66 million Americans are obese, says a December study, and top New Year's Resolutions include losing weight. A bariatrics patient and her Loyola surgeon weigh-in on tips and advice.
On Tuesday, December 4 and Friday, December 7, orthopedic surgeons at Porter Adventist Hospital will provide free hip and knee replacements to 14 patients from the Denver area as part of Operation Walk USA 2012.
A randomized, double-blind clinical trial by researchers at Hospital for Special Surgery has revealed that corticosteroids are more effective than the more expensive treatment in providing pain relief to patients with thumb arthritis.
Two new studies by researchers at Hospital for Special Surgery have overturned common beliefs about joint replacement in patients with lupus and rheumatoid arthritis.
Richard Iorio, MD, Named Chief, Division of Adult Reconstructive Surgery; will oversee the Department of Orthopaedic Surgery’s total joint replacement programs and clinical research studies.
For those suffering from osteoarthritis of the knees or hands, applying topical non-steroidal anti-inflammatory drugs (NSAIDs) —in the form of creams, gels and patches —can bring weeks of pain relief, finds a new review by The Cochrane Library.
Researchers at the University of California, San Diego – led by Gary S. Firestein, professor in the Division of Rheumatology, Allergy and Immunology at UC San Diego School of Medicine – investigated a mechanism usually implicated in cancer and in fetal development, called DNA methylation, in the progression of rheumatoid arthritis (RA). They found that epigenetic changes due to methylation play a key role in altering genes that could potentially contribute to inflammation and joint damage.
In the realm of deadly and disabling diseases, conditions such as cancer and Alzheimer’s seem to attract the most media attention. But there are others that take a similarly high toll, and rheumatoid arthritis is one of them, Mayo Clinic researchers say.
Benaroya Research Institute and Novo Nordisk collaborate on autoimmune disease research. Groundbreaking agreement aims to achieve better, faster diagnosis and treatment of rheumatoid arthritis, inflammatory bowel disease and lupus.
A simple blood test may help physicians track the progression of rheumatoid arthritis disease activity, say researchers at UAB. The international research team says that a blood test measuring 12 biomarkers for RA is a valid and potentially useful tool in managing the disease.
Ten-year-old Cheyanne Campo has achieved a lofty goal, despite – and because of – a sometimes painful disease. She has raised more than $500 for the Arthritis Foundation and will be participating in the organization’s annual Arthritis Walk on June 23 in Battery Park.
Larger-than-normal populations of specific gut bacteria may trigger the development of diseases like rheumatoid arthritis and possibly fuel disease progression in people genetically predisposed to this crippling and confounding condition, say the researchers, who are participating in the Mayo Illinois Alliance for Technology Based Healthcare.
Special echocardiograms show promise for early detection of a potentially deadly complication in rheumatoid arthritis: heart disease, Mayo Clinic research shows.
Research demonstrates how dying or damaged brain cells give rise to autoantibodies in blood that can be reliable biomarkers for early AD diagnosis. Key mechanism mirrors process common to autoimmune disorders.