A protein used by embryo cells during early development, and recently found in many different types of cancer, apparently serves as a switch regulating the spread of cancer, known as metastasis, report researchers at the University of California, San Diego School of Medicine and UC San Diego Moores Cancer Center in the June 15, 2013 issue of the journal Cancer Research.
Wake Forest Baptist Medical Center researchers conducted a study to evaluate the heat indexes in migrant farmworker housing and found that a majority of the workers don’t get a break from the heat when they’re off the clock.
After laboring under other theories that never seemed to add up, McMaster University researchers have concluded that menopause is an unintended outcome of natural selection, generated by men's historical preference for younger mates.
States that want to reduce rates of adult smoking may consider implementing stringent tobacco restrictions on teens.Washington University researchers discovered that states with more restrictive limits on teens purchasing tobacco also have lower adult smoking rates, especially among women.
Slowdowns in the transport of materials within neurons may be the root cause of ALS and other neurodegenerative diseases.
Despite government efforts to expand diagnostic criteria for pelvic inflammatory disease, ER doctors are not identifying the condition any more often in adolescent girls, finds a new study in Journal of Adolescent Health.
Monell researchers identified odorants from human skin cells that can be used to identify melanoma, the deadliest form of skin cancer. In addition a nanotechnology-based sensor could reliably differentiate melanoma cells from normal skin cells. Non-invasive odor analysis may be a valuable technique in the detection and early diagnosis of human melanoma.
As anyone who’s ever mixed up the sugar and salt while baking knows, too much of a good thing can be inedible. What hasn’t been clear, though, is how our tongues and brains can tell when the saltiness of our food has crossed the line from yummy to yucky — or, worse, something dangerous.
E. coli that produce a toxin dangerous to humans may survive longer in water than benign counterparts, a new study finds.The findings have implications for water quality testing, suggesting that a lake's overall E. coli population may be a poor indicator of danger.
The keen vision of NASA's Hubble Space Telescope has detected a mysterious gap in a vast protoplanetary disk of gas and dust swirling around the nearby star TW Hydrae, located 176 light-years away in the constellation Hydra (the Sea Serpent). The gap's presence is best explained as due to the effects of a growing, unseen planet that is gravitationally sweeping up material and carving out a lane in the disk, like a snow plow.
1) ALMA Takes Close-up of Matter Spiraling Toward a Black Hole: The new Atacama Large Millimeter/submillimeter Array (ALMA) telescope gets a close view of gas spiraling toward a supermassive black hole at the center of a galaxy 45 million light-years away. 2)VLBA Makes Most Accurate Pulsar Distance Measurement: The accuracy of the new pulsar measurement promises to help in the quest to detect the elusive gravitational waves predicted by General Relativity. 3) NRAO Engineer Earns Patent for New 'Reflectionless' Filter: A clever new design for a signal filter could help reduce unwanted noise in the electronics that enable radio astronomy observations.
Study is first step towards generating patient-specific blood products for cell-replacement therapy.
Researcher Michael S. Irwig, M.D., F.A.C.E., assistant professor of medicine at the George Washington University School of Medicine and Health Sciences and director of the Center for Andrology at The GW Medical Faculty Associates, found that men who used the medication finasteride (Propecia) and developed persistent sexual side effects, are also drinking less alcohol than before.
Precisely what causes breast cancer recurrence has been poorly understood. But now a piece of the puzzle has fallen into place: Researchers have identified a key molecular player in recurrent breast cancer – a finding that suggests potential new therapeutic strategies.
Reducing levels of nerve-growth factor may be a key to developing better pain treatments.
According to market research from Saint Joseph's University, gender diversity is lacking across all leadership levels within the insurance industry. Primary author Mike Angelina, executive director of Saint Joseph's Academy of Risk Management and Insurance, is hopeful his findings will call on businesses to address gender inequality, saying employing females in leadership roles will lead to a more diverse workforce and potentially better represent the underlying customer demographics.
Researchers at Case Western Reserve University have found that a single gene poses a double threat to disease: Not only does it inhibit the growth and spread of breast tumors, but it also makes hearts healthier.
In women at high risk for breast cancer, a long-term drug treatment can cut the risk of developing the disease in half. NIH-funded researchers have identified two gene variants that may predict which women are most likely to benefit from this therapy.
Newly discovered genetic variations may help predict breast cancer risk in women who receive preventive breast cancer therapy with the selective estrogen receptor modulator drugs tamoxifen and raloxifene, a Mayo Clinic-led study has found. The study is published in the journal Cancer Discovery.
Genetic variations, known as SNPs, in or near the genes ZNF423 and CTSO were associated with breast cancer risk among women who underwent prevention therapy with tamoxifen and raloxifene, according to data published in AACR's Cancer Discovery.
A new University of Florida study suggests a promising brain-imaging technique has the potential to improve diagnoses for the millions of people with movement disorders such as Parkinson’s disease.
U-M Health System findings identify new drug target to prevent muscle weakness and loss after common and serious knee injury among athletes.
A team of researchers led by the University of Iowa is recommending clinical guidelines that will cut the post-surgical infection rate for staph bacteria (including MRSA) by 71 percent and 59 percent for a broader class of infectious agents known as gram-positive bacteria. The recommendations come after an extensive review of hospital practices in the U.S. and are published in the British Medical Journal.
Latest research findings by scientists at the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) could enable early screening of patients with hepatocellular carcinoma (HCC), a major form of liver cancer, for more aggressive treatment to improve survival rate. The researchers have also proposed a way to inactivate SALL4 - a stem cell gene - to kill HCC cells and block tumour formation.
Sleep researchers from UC Riverside and UC San Diego have identified the sleep mechanism that enables the brain to consolidate emotional memory and found that a popular prescription sleep aid heightens the recollection of and response to negative memories.
The ability to distinguish odors declines with age. A study shows that African-Americans have a greater decrease than Caucasians. This has serious consequences. Olfactory loss often leads to impaired nutrition. It can be an early warning sign of neurodegenerative diseases, and can predict death.
Nationwide school survey shows availability of sugar- and fat-laden foods and drinks.
Men who experience restless legs syndrome (RLS) may have a higher risk of dying earlier, according to research that appears in the June 12, 2013, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Young adults who deem themselves “spiritual but not religious” are more likely to commit property crimes — and to a lesser extent, violent ones — than those who identify themselves as either “religious and spiritual” or “religious but not spiritual,” according to Baylor University researchers.
Scientists have measured a significant and potentially pivotal difference between the brains of patients with an inherited form of Alzheimer’s disease and healthy family members who do not carry a mutation for the disease.
Scientists at The Scripps Research Institute have found evidence that an emotion-related brain region called the central amygdala—whose activity promotes feelings of malaise and unhappiness—plays a major role in sustaining cocaine addiction.
Many plants are self-fertilizing, meaning they act as both mother and father to their own seeds. This strategy – known as selfing – guarantees reproduction but, over time, leads to reduced diversity and the accumulation of harmful mutations. A new study published in the scientific journal Nature Genetics shows that these negative consequences are apparent across a selfing plant’s genome, and can arise more rapidly than previously thought.
Genetic research published June 12 in Nature by scientists from the University of Delaware and Woods Hole Oceanographic Institution reveals active bacteria, fungi and other microbes living in 5 million-year-old ocean sediment.
Two Indiana U. studies highlight the impact work and financial stress can have on health behaviors. The lead author urges workplace wellness programs to consider such impacts as the economy sputters along.
Multiple drug classes commonly prescribed for common medical conditions are capable of influencing the onset and progression of Alzheimer’s disease.
Mammals possess the remarkable ability to regenerate a lost fingertip, including the nail, nerves and even bone. In humans, an amputated fingertip can sprout back in as little as two months, a phenomenon that has remained poorly understood until now. In a paper published today in the journal Nature, researchers at NYU Langone Medical Center shed light on this rare regenerative power in mammals, using genetically engineered mice to document for the first time the biochemical chain of events that unfolds in the wake of a fingertip amputation. The findings hold promise for amputees who may one day be able to benefit from therapies that help the body regenerate lost limbs.
A recent study, led by researchers at the Johns Hopkins Bloomberg School of Public Health and Huashan Hospital, Fudan University, has identified a new mechanism for PZA-resistance, which provides new insight into the how this mysterious drug works. The study is available online June 12 in the journal Emerging Microbes and Infections.
Despite a critical shortage of primary care in the United States less than 25 percent of newly minted doctors go into this field and only a tiny fraction, 4.8 percent, set up shop in rural areas, according to a study just released in the “Published Ahead-of-Print” section in Academic Medicine by researchers at the George Washington University School of Public Health and Health Services (SPHHS).
How will full implementation of the Affordable Care Act (ACA) affect the work and goals of state and local public health departments—and how can public health personnel contribute to the success of health care reform? The experience in Massachusetts has some important lessons, according to an article published online by the Journal of Public Health Management and Practice. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
People who have obstructive sleep apnea -- when a person stops breathing for periods during sleep -- have a greater risk of sudden cardiac death, according to a study published online today in the Journal of the American College of Cardiology. An estimated 12 million American adults have obstructive sleep apnea, and many of them are undiagnosed, according to the National Heart, Lung and Blood Institute (NHLBI).
Georgia Tech research published online Monday in Nature Communications indicates that diatoms stuff more iron into their silica shells than they actually need. As a result, there’s not enough iron to go around, and the added iron during fertilization experiments may stimulate less productivity than expected. The study also says that the removal of iron through incorporation into diatom silica may be a profound factor controlling the Southern Ocean’s bioavailable pool of iron, adversely affecting the ecosystem.
For patients undergoing surgery on the cervical (upper) spine, overall rates of complications and death are higher at teaching hospitals than at non-teaching hospitals, reports a study in the June 1 issue of Spine. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
Stress felt by dad—whether as a preadolescent or adult—leaves a lasting impression on his sperm that gives sons and daughters a blunted reaction to stress, according to a new preclinical study in the Journal of Neuroscience by researchers at the University of Pennsylvania. The findings point to a never-before-seen epigenetic link to stress-related diseases such as anxiety and depression passed from father to child.
Teenage victims of cyberbullying, defined as the use of the internet or cell phones to send hurtful and harassing messages, are more likely to develop symptoms of depression, substance abuse and internet addiction, reports a new study in the Journal of Adolescent Health.
The more an older man walks, the better his physical and mental health and his quality of life are likely to be, finds a new study in the American Journal of Health Promotion.
Teens don’t necessarily follow in their parents’ footsteps when it comes to physical activity, finds a new study in the Journal of Adolescent Health.
Most teens have unsupervised access to their prescription drugs at home, including drugs with potential for abuse, finds a new study in the Journal of Adolescent Health.
Black women with breast cancer are more likely than Hispanic or white women to experience delays in the initiation of chemotherapy or radiation after surgery, finds a new study in Health Services Research.
Victims of trauma are at higher risk of either dying or suffering a major complication if they are treated at a hospital that serves a large population of black patients, finds a new study in Health Services Research.
Seeking to improve the lives of sickle cell anemia sufferers around the world, researchers from the La Jolla Institute for Allergy and Immunology, the Dana-Farber/Children's Hospital Cancer Center in Boston and the BloodCenter of Wisconsin in Milwaukee and others are preparing to launch Phase II of a clinical trial to investigate a potential new therapy for reducing the disorder’s severest symptoms. More than 100,000 Americans and several million people worldwide suffer from this genetic disorder.
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