During the past 17 years, there has been a remarkable increase in scientific research concerning chronic traumatic encephalopathy (CTE) with researchers at the BU CTE Center at the forefront.
For the more than 6 million Americans living with Alzheimer’s disease, related dementias, or mild cognitive impairment, anxiety is often an accompanying challenge. A Florida State University psychologist has received a five-year, $3.7 million grant from the National Institute on Aging to study intervention techniques that aim to combat anxiety in these groups and improve quality of life.
People with early cardiovascular disease may be more likely to have memory and thinking problems and worse brain health in middle age, according to new research published in the January 25, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.
University of Maryland School of Medicine’s researchers have discovered that a certain type of cell that sits on top of the brain’s smallest blood vessels senses when their brain region needs energy. When glucose levels are low, these cells signal blood vessels to dilate, increasing the blood flow regionally and allowing more energy to fuel that part of the brain.
UC San Diego Herbert Wertheim School of Public Health and Human Longevity Science study: senior women were less likely to develop mild cognitive impairment or dementia if they did more daily walking and moderate-to-vigorous physical activity.
High blood pressure and diabetes are known risk factors for stroke, but now a new study shows that the amount of risk may decrease as people age. The study is published in the January 18, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Vision impairment disproportionately impacts older adults
Findings highlight potential benefit of hearing aid use
Their older parents need care. Their kids are still under 18. And they probably have a job, too. They’re the “sandwich generation” – a longtime nickname for the mostly female, mostly middle-aged group of Americans who serve as caregivers for both older and younger family members at once. A new study estimates there are at least 2.5 million of them, while giving a detailed view into who they are, and which older adults rely on them.
Researchers at Tufts University have completed the first study examining levels of vitamin D in brain tissue, specifically in adults who suffered from varying rates of cognitive decline. They found that members of this group with higher levels of vitamin D in their brains had better cognitive function.
Regenstrief Institute Research Scientist April Savoy, PhD, a human factors engineer and health services researcher, is developing and testing user-friendly health information tools and technology designed to enhance accessibility and value to older adults with both diabetes and Alzheimer’s disease, and their caregivers.
Some people report a decline in their memory before any decline is large enough to show up on standard tests. This experience, called subjective cognitive decline, is associated with an increased risk of later developing dementia in white, Black and Latino people, according to a study published in the November 30, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology.
A Cornell-led collaboration used machine learning to pinpoint the most accurate means, and timelines, for anticipating the advancement of Alzheimer’s disease in people who are either cognitively normal or experiencing mild cognitive impairment.
People who eat or drink more foods with antioxidant flavonols, which are found in several fruits and vegetables as well as tea and wine, may have a slower rate of memory decline, according to a study published in the November 22, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology.
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The Penn Artificial Intelligence and Technology Collaboratory for Healthy Aging (PennAITech) – made up of Penn’s School of Nursing, the Perelman School of Medicine, and other departments across the University – focuses on identifying developing, evaluating, commercializing, and disseminating innovative technology and artificial intelligence methods/software to support aging. It’s made possible through a grant from the National Institute on Aging, a part of the National Institutes of Health. In its first year, and through a competitive national grant review process, twelve applicants from academia, industry, and clinical practice across the United States have been selected for funding.
A new approach to stem cell therapy that uses antibodies instead of traditional immunosuppressant drugs robustly preserves cells in mouse brains and has potential to fast-track trials in humans, a Michigan Medicine study suggests.
Drug companies and university-based teams are working urgently to find and test new medications that could prevent or slow the decline of brain function in older adults. But a new study suggests they’ll need to work harder to find volunteers for their clinical trials.
Researchers at UC San Diego report that a polygenic hazard score based on 290 genetic variants could be an effective tool for predicting genetic risk of lethal prostate cancer, which kills more than 34,000 men in the U.S. annually.
Telehealth follow-up consultations following an emergency department visit were associated with 28 more repeat ED encounters and nearly 11 more return hospital admissions per 1000 patients compared with in-person follow-ups,
About one in 10 seniors who live in cities reported that they use public transportation, and 20 percent of older transit users said they relied on trains and buses to get to their doctor appointments.
While hormone therapy was associated with higher self-reported quality of life in white women, Black women actually experienced lower overall quality of life under the same treatment.
Investigators from the departments of Neurology, Neurosurgery, Psychiatry, Medicine, and Biomedical Sciences at Cedars-Sinai have shown that an immune-suppressing drug similar to one used to treat severe COVID-19 reversed symptoms of delirium in mice whose lungs were injured during mechanical breathing assistance.
A highly innovative method using the latest technology has generated a comprehensive list of SARS-CoV-2 viral and human proteins that interact with each other, with one such interaction showing the virus directly influencing proteins that regulate the human immune system.
In 2015, published findings from the landmark Systolic Blood Pressure Intervention Trial (SPRINT) showed that intensive blood pressure management reduced cardiovascular disease and lowered the risk of death. In 2019, results of the SPRINT MIND trial showed that lowering blood pressure also reduced the risk of mild cognitive impairment in older adults. Now, researchers from Wake Forest University School of Medicine have shown that while intensive blood pressure control was beneficial to SPRINT participants’ health during the trial, the benefits for cardiovascular mortality went away after approximately two years when protocols for blood pressure management were no longer being followed.
Wake Forest University School of Medicine has received a five-year, $30 million grant to test a novel rehabilitation program designed for older patients hospitalized for acute heart failure.
The National Institutes of Health's National Institute on Aging (NIA) recently awarded researchers from Indiana University's School of Public Health-Bloomington and School of Medicine $3.96 million to fund a five-year, randomized clinical trial of an Alzheimer’s disease and related dementia (ADRD) telehealth intervention.
A new model to predict the life expectancy of older people relies less on their specific disease diagnoses and more on factors such as the ability to grocery shop, the amount of certain small cholesterol particles circulating in their blood, and whether they never or only occasionally smoked.
Irvine, Calif., Sept. 20, 2022 — What began with a $70,000 philanthropic gift 12 years ago has grown into the recipient of a $47 million National Institute on Aging grant for Alzheimer’s disease research at the University of California, Irvine. The funds will be parceled out over five years to a UCI team developing the next generation of mouse models for studying late-onset Alzheimer’s.
One of the most upsetting aspects of age-related memory decline is not being able to remember the face that accompanies the name of a person you just talked with hours earlier.
A team of researchers at the University of Kentucky’s Sanders-Brown Center on Aging (SBCoA) has been awarded a $20.5 million grant from the National Institute on Aging (NIA) of the National Institutes of Health (NIH). The P01 award exemplifies team science, helping to support about 35 researchers across six different labs who will be working on four main projects, all with a common theme.
Researchers from Florida Atlantic University, in collaboration with Tel Aviv University, have received a two-year, $379,177 grant from the National Institute on Aging, National Institutes for Health, on a collaborative project to study mood-disorders changes in Alzheimer’s disease.
UC San Diego Herbert Wertheim School of Public Health and Human Longevity study asked whether associations between physical activity and sedentary time with death varied based on different levels of genetic predisposition for longevity.
A study that assessed the brains of 99 World Trade Center (WTC) responders showed that WTC responders with cognitive impairment (CI) and post-traumatic stress disorder (PTSD) have a different presentation of the white matter in their brains compared to responders with CI without PTSD.
Linda J. Van Eldik, Ph.D., director of the University of Kentucky Sanders-Brown Center on Aging, is part of a $1.5 million grant to help further research into a possible treatment for Alzheimer’s disease. A four-year grant from the National Institute on Aging of the National Institutes of Health to Northwestern University includes a $611,676 subaward to UK. Van Eldik, the Dr. E. Vernon Smith and Eloise C. Smith Alzheimer's Research Endowed Chair, serves as principal investigator on UK’s award.
Timothy Huang, Ph.D., has been awarded $2.8 million by the National Institute on Aging (NIA) to continue his work on Alzheimer’s disease. The four-year project will use human stem cells transplanted into mice to determine the role of specific Alzheimer’s-related gene mutations in the brain.
Researchers will study telehealth behavioral interventions among adults 50 and older with excess weight and cardiometabolic risk factors.
The National Institute on Aging (NIA) and the National Institutes of Health (NIH) awarded Ochsner Health a $700,000 grant to study the effectiveness of its collaborative dementia care through the Ochsner Neuroscience Institute’s Brain Health and Cognitive Disorders Program.
A look into how environmental variables accelerate, slow or even reverse the aging process is the focus of a University of Oregon anthropologist whose research was recently funded by the National Institutes of Health.
A new study compares two approaches to improving memory in people with mild cognitive impairment.
Researchers found significant differences in movement patterns between participants with normal cognition and those with mild cognitive impairment or Alzheimer’s disease.
To build a resource that greatly expands Alzheimer’s disease genetic studies in the currently underrepresented African ancestry populations and Hispanic/Latinx groups, the John P. Hussman Institute for Human Genomics (HIHG) at the University of Miami Miller School of Medicine will lead a major five-year, international, multi-site initiative with Case Western Reserve University, Columbia University, Wake Forest University, the University of Pennsylvania, and the University of Ibadan, which is the lead institution for the African Dementia Consortium (AfDC).
A recent publication from researchers at the University of Kentucky explains the importance of identifying and understanding how differences between tissues and cells alter gene expression without changing the underlying genetic code.
A new biomedical research tool that enables scientists to measure hundreds of functional proteins in a single cell could offer new insights into cell machinery. Details about the cyclic microchip assay method are published in the journal Nature Communications.
Medicare could waste up to $605 million per year on the controversial Alzheimer’s drug aducanumab if it is eventually approved for widespread use because it is supplied in vials containing fixed doses that may not be appropriate for all patients–resulting in the trashing of large volumes of unused drug
Newly identified genes may help explain why women experience different heart disease symptoms than men do, which often leads to misdiagnosing serious problems.
An important new study of diverse communities is looking at how brain changes, genetics and other factors contribute to dementia and Alzheimer’s disease. The results could affect millions. Among people 65 and older, about 1 in 9 has Alzheimer’s disease.
Nearly all older adults have experienced some form of ageism in their everyday lives, a new study finds -- whether it’s seeing ageist messages and images on television or the internet, encountering people who imply that they’re less capable just because they’re older, or believing stereotypes about aging.
Researchers at UC San Diego have received a $25.6 million grant from the National Institutes of Health and National Institute on Aging to continue the Study of Latinos-Investigation of Neurocognitive Aging, a 12-year assessment of cognitive and brain aging and impairment among aging Latinos.
New research shows that comorbidities such as chronic kidney disease are associated with higher plasma p-tau levels.
Johns Hopkins Medicine researchers say they discovered that a special sugar molecule could play a key role in the development of Alzheimer’s disease. If further research confirms the finding, the molecule, known as a glycan, could serve as a new target for early diagnostic tests, treatments and perhaps prevention of Alzheimer’s disease, say the researchers.
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