In a significant stride towards personalized cancer care, the National Cancer Center Japan (NCCJ) has marked a decade of progress in cancer genomic medicine (CGM). A comprehensive review outlines the evolution of CGM in Japan, highlighting the pivotal role of the NCCJ in this advancement. The study encapsulates the historical milestones, current achievements, and future directions in the field of CGM.
A recent study in gastrointestinal (GI) cancer research reveals a promising advancement in predicting patient responses to immune checkpoint inhibitor (ICI) therapy. The newly developed DNA damage response-related immune activation (DRIA) signature could serve as a groundbreaking biomarker, providing valuable guidance for ICI therapy decisions.
Susan G. Komen believes final recommendations made by the U.S. Preventive Services Task Force (USPSTF) on screening mammography diminish the significance of regular screening mammography and could exacerbate the troubling fact that 25% of eligible women have foregone mammograms in the past two years.
Challenges remain in ensuring equitable access to screening and addressing gaps in evidence regarding supplemental screening modalities and the adoption of artificial intelligence (AI) technologies, notes Joann Elmore, MD, MPH, a professor of medicine at the David Geffen School of Medicine at UCLA in a newly published editorial in JAMA.
A groundbreaking study has recognized the cGAS-STING signaling pathway as a formidable ally in the immune system's battle against cancer. This pivotal discovery may pave the way for innovative immunotherapies capable of amplifying the body's inherent defenses to detect and eradicate cancer cells, signifying a substantial advance towards more potent cancer treatments.
The final United States Preventive Services Task Force (USPSTF) Breast Cancer Screening Recommendations, while an improvement over previous guidance, do not go far enough to save more women’s lives. Women at average risk for breast cancer should start annual screening at age 40.
Moffitt Cancer Center has launched a pioneering clinical trial for patients with late-stage non-small cell lung cancer whose disease has progressed following initial frontline standard of care immunotherapy that includes an immune checkpoint inhibitor alone or combined with chemotherapy.
While skin cancer is one of the most preventable types of cancer, a recent survey of more than 1,000 U.S. adults found that an increasing number of Americans are reporting sunburn despite knowing how to protect themselves from the sun’s harmful rays.
Cedars-Sinai Guerin Children’s pediatric oncologist Leo Mascarenhas, MD, MS, has been reelected as Children’s Oncology Group (COG) voting body chair for a second five-year term.
The Vineyard Cares Business of the Year Award celebrates Huntsman Cancer Institute’s plan to establish a comprehensive cancer center in Vineyard, which will bring crucial cancer research and care closer to more communities in the region.
Naples (FL) firefighter, David Perez, initially kept his cancer diagnosis quiet, but now speaks out about the importance of fire fighter health and cancer in the fire service. “My eyes really opened up as to how many firefighters have been diagnosed with cancer and how many people there [Sylvester’s Firefighter Cancer Initiative] are fighting for us,” Perez said.
A national study led by researchers at The University of Texas MD Anderson Cancer Center and The University of New Mexico (UNM) Comprehensive Cancer Center found major gaps in breast, cervical and colorectal cancer screening use in Federally Qualified Health Centers (FQHCs) in the US, relative to overall screening rates in the country.
A national study led by researchers at The University of Texas MD Anderson Cancer Center and The University of New Mexico (UNM) Comprehensive Cancer Center found major gaps in breast, cervical and colorectal cancer screening use in Federally Qualified Health Centers (FQHCs) in the U.S., relative to overall screening rates in the country.
A new study examining the role of aspirin in breast cancer treatment reveals critical issues related to health equity and aging that have broad implications for cancer and other disease intervention trials, say researchers from Georgetown University’s Lombardi Comprehensive Cancer Center.
By examining which genes were turned on and off in a mix of cell types from breast cancer biopsies, a team led by UT Southwestern Medical Center researchers developed a tool that can accurately predict which patients with breast cancer will respond to immunotherapies.
The University of Texas MD Anderson Cancer Center and RUSH University System for Health today announced a partnership to create RUSH MD Anderson Cancer Center.
RWJBarnabas Health and Rutgers Cancer Institute of New Jersey, the state’s only National Cancer Institute-designated Comprehensive Cancer Center, have announced that Eileen White, PhD, Deputy Director and Chief Scientific Officer at Rutgers Cancer Institute, has been elected as a member of the American Academy of Arts and Sciences.
Legislation signed by Gov. Phil Scott eliminates out-of-pocket expenses for diagnostic and supplemental imaging, which is crucial in ruling out breast cancer and a standard form of imaging for people at high-risk of breast cancer and survivors.
Explore how research targeting EP300/CBP protein in Group 3 medulloblastoma may advance targeted pediatric brain tumor treatments by inhibiting bromodomains.
Faculty, scientists, and urologists from UCLA Health Urology will present research data on the latest discoveries and innovations in urology at the 2024 American Urological Association’s (AUA) Annual Meeting in San Antonio, Texas, May 3-6.
A new study led by researchers at the American Cancer Society (ACS) showed people surviving cancer who reported feeling more lonely experienced a higher mortality risk compared to survivors reporting low or no loneliness.
The Foundation for the Accreditation of Cellular Therapy (FACT) has once again awarded Rutgers Cancer Institute of New Jersey and Robert Wood Johnson University Hospital’s (RWJUH) Transplant and Cell Therapy Program accreditation under the FACT-JACIE International Standards for Hematopoietic Cellular Therapy
Shutting down a gene called PRMT5 stopped metastatic estrogen receptor-positive (ER+) breast cancer cells from growing after they acquired resistance to a standard therapy known as CDK4/6 inhibitors, UT Southwestern Medical Center researchers showed in a new study.
Mickey Allen was 89 years old when she was diagnosed with Stage 3B lung cancer. How did her age impact her treatment options? University of Chicago Medicine oncologists explain what factors they consider when creating treatment plans for patients in their 80s and 90s.
The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.
Mercy BioAnalytics, Inc., a pioneer in extracellular vesicle-based liquid biopsy for the early detection of cancer, will present data at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting showing the performance of its Mercy Halo™ Ovarian Cancer screening test in a large cohort of asymptomatic, postmenopausal women.
A Ludwig Cancer Research study has discovered how a lipid molecule found at high levels within tumors undermines the anti-cancer immune response and compromises a recently approved immunotherapy known as adoptive cell therapy (ACT) using tumor infiltrating lymphocytes, or TIL-ACT.
Learn how ancestry changes genetic risk variants’ impact on type 2 diabetes in childhood cancer survivors & alkylating agent exposure magnifies diabetes risk.
Socioeconomic factors are preventing some patients from accessing common treatment to stop progression of multiple myeloma.
Investigadores de Mayo Clinic han utilizado un nuevo enfoque de la quimioterapia para más que duplicar la tasa de supervivencia típica de los pacientes con cáncer de estómago y metástasis peritoneal, es decir, del cáncer que se ha diseminado al revestimiento de la cavidad abdominal, según un estudio publicado en Anales de Oncología Quirúrgica.
Pesquisadores da Mayo Clinic utilizaram uma nova abordagem à quimioterapia para mais do que dobrar a taxa de sobrevivência típica dos pacientes com câncer de estômago e metástase peritoneal, ou seja, do câncer que se espalhou para o revestimento da cavidade abdominal, de acordo com um estudo publicado nos Anais da Oncologia Cirúrgica.
The FDA approval was based on results of the QUILT 3.032 clinical trial, which was led by Dr. Karim Chamie, associate professor urology at the David Geffen School of Medicine at UCLA and a researcher at the UCLA Health Jonsson Comprehensive Cancer Center.
An intricate simulation performed by UT Southwestern Medical Center researchers using one of the world’s most powerful supercomputers sheds new light on how proteins called SNAREs cause biological membranes to fuse.
New research by scientists at University of California San Diego has shown that cells regulate cAMP/PKA signaling by forming liquid droplets that segregate excess PKA catalytic subunits where they can do no harm. Some cancers may block the formation of liquid droplets, leading to hyperactive signaling and tumor formation.
Researchers in the College of Engineering explore a cancer immunotherapy treatment that involves activating the immune cells in the body and reprogramming them to attack and destroy cancer cells. This therapeutic method frequently uses cytokines, small protein molecules that act as intercellular biochemical messengers and are released by the body's immune cells to coordinate their response.
Liver inflammation, a common side-effect of cancers elsewhere in the body, has long been associated with worse cancer outcomes and more recently associated with poor response to immunotherapy. Now, a team led by researchers from the Abramson Cancer Center and Perelman School of Medicine at the University of Pennsylvania has found a big reason why.
Researchers at the University of Michigan Rogel Cancer Center have developed a new urine-based test that addresses a major problem in prostate cancer: how to separate the slow-growing form of the disease unlikely to cause harm from more aggressive cancer that needs immediate treatment.
A new Moffitt Cancer Center study published in the journal Immunity offers insight into how lung cancer cells evade the protective immune system, potentially opening a door for novel antibody-based immunotherapies. Their study centers on a molecule called Jagged2, which plays a primary role in fueling the aggressiveness and immune evasion capacity of lung cancer.
Using spatial analysis of tissue samples, Cedars-Sinai investigators have identified patterns that could predict whether patients with the most common type of ovarian cancer will experience early relapse after treatment.
In patients undergoing colonoscopy to screen for colorectal cancer, deeper sedation using the anesthetic drug propofol may improve detection of "serrated" polyps — a type of precancerous lesion that can be difficult to detect, reports a study in the Online First edition of Anesthesiology, the peer-reviewed journal of the American Society of Anesthesiologists (ASA).
The National Comprehensive Cancer Network® (NCCN®)—an alliance of leading cancer centers—announces 2024 award recipients that include individuals and groups who have made significant and noteworthy impacts on improving cancer care and supporting NCCN’s mission to help all people with cancer to live better lives.
New research in the April 2024 issue of JNCCN—Journal of the National Comprehensive Cancer Network showcases the feasibility of improving early detection and prevention for pancreatic cancer.
Moffitt Cancer Center has treated its first patient in an investigator-initiated, phase 1 clinical trial investigating the safety and efficacy of a chimeric antigen receptor T-cell (CAR T) therapy for prostate cancer that has metastasized to the bone.
For patients with locally advanced prostate cancer, combined treatment with chemotherapy and hormonal therapy offers extended control of prostate-specific antigen (PSA) levels, compared to hormonal therapy alone, reports a study in the April issue of The Journal of Urology®, an Official Journal of the American Urological Association (AUA). The journal is published in the Lippincott portfolio by Wolters Kluwer.
Researchers from the University of Michigan Health Rogel Cancer Center have created a urine-based test that detects pieces of DNA fragments released by head and neck tumors. The test could potentially facilitate early detection of this cancer type, which currently does not have a reliable screening method.
UWF faculty, serving as evaluators for Florida's Cancer Prevention and Control Program since 2018, recently had their contract renewed for $680,000 over four years due to excellent performance, as acknowledged by the CDC.
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