Feature Channels: Cell Biology

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Here are some of the latest articles that have been added to the Behavioral Science channel on Newswise, a free source for journalists.

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By simulating molecular dynamics, scientists from St. Jude Children’s Research Hospital revealed how the selectivity or promiscuity of GPCR coupling relies on the location and duration of intermolecular interactions.

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Periprosthetic joint infection (PJI) is a devastating complication of knee and hip replacement surgery that can, in some cases, be difficult to distinguish from other causes of arthroplasty failure. An "omics"-based tool that measures predicted abundance of immune cells may aid in making the diagnosis of failed arthroplasty due to PJI, suggests a study in The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio in partnership with Wolters Kluwer.

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SEATTLE — Dec. 1, 2022 — The 64th Annual Meeting and Exposition of the American Society of Hematology (ASH) will take place virtually and in person Dec. 10-13 in New Orleans, Louisiana.

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Immune T cells are continuing to target the spike protein of SARS-CoV-2 variants of concern, although mutations are making some T cells less effective, according to new research.

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An interdisciplinary team of scientists from Cologne, Heidelberg and Munich have discovered a new function of a well-known enzyme: The signal peptidase complex in the endoplasmic reticulum cleaves faulty membrane proteins to initiate their degradation.

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An antibody that was invented at UNC Charlotte could be used to curb pancreatic cancer relapse and metastasis, a new UNC Charlotte study has found. Pancreatic cancer is the 10th most common type of cancer, but it is the fourth-leading cause of cancer death among men and women in the United States.

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Columbia researchers invent new method to treat obesity by using cationic nanomaterials that can target specific areas of fat and inhibit the unhealthy storage of enlarged fat cells. “Our studies highlight an unexpected strategy to treat visceral adiposity and suggest a new direction of exploring cationic nanomaterials for treating metabolic diseases,” said Columbia Engineering’s Biomedical Engineering Prof Kam Leong, a pioneer in using polycation to scavenge pathogens.

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Researchers discover that dual knockout of genes in organoids grown from human tissue generates a model of and potential therapeutic target for gastroesophageal junction cancer

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Shirin Bahmanyar, associate professor in the Department of Molecular Cellular and Developmental Biology at Yale University, has received the 2022 Women in Cell Biology (WICB) Junior Award for Excellence in Research. She will give the talk “Regulation of lipid metabolism from the nuclear envelope” on Sunday, December 4, at Cell Bio 2022 in Washington, DC.

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The origin of all biological movements, including walking, swimming, or flying, can be traced back to cellular movements; however, little is known about how cell motility arose in evolution.

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The Public Policy Committee of the American Society for Cell Biology selected George Langford to receive the 2022 Public Service Award for his 50 years of service to the ASCB and science. A short video of the presentation will be shown on Saturday, December 3, during the Cell Bio 2022 Keynote in Washington, DC.

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Cell Bio 2022—the annual joint meeting of the American Society for Cell Biology (ASCB) and the European Molecular Biology Organization (EMBO)—will convene at the Walter E. Washington Convention Center in Washington, DC, December 3-7. As the world's largest gathering of cell biologists, this unique meeting focuses on cell biology as the fundamental basis of biology and sessions on emerging interdisciplinary topics.

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Needhi Bhalla, Professor of Molecular, Cell, and Developmental (MCD) Biology at the University of California, Santa Cruz (UCSC), will receive the 2022 American Society for Cell Biology Prize for Excellence in Inclusivity award. ASCB will recognize Bhalla on Saturday, December 3, before the keynote of the Cell Bio 2022 meeting in Washington, DC.

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Rebecca Heald, Professor, and Co-chair in the Department of Molecular and Cell Biology at the University of California, Berkeley, has been awarded the 2022 Sandra K. Masur Senior Leadership Award from the American Society for Cell Biology (ASCB). Heald will present the talk “Molecular conflicts disrupting centromere maintenance contribute to Xenopus hybrid inviability” during the Centromere Structure and Function Special Interest Subgroup Wednesday, December 7, at Cell Bio 2022. The Masur Award is presented on Tuesday, December 6.

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The American Society for Cell Biology honors David J. Asai, Senior Director of Science Education for the Howard Hughes Medical Institute (HHMI), with the 2022 Bruce Alberts Award for Excellence in Science Education. Asai will receive the award on Monday, December 5, during Cell Bio 2022 in Washington, DC, where he will present the talk “Lessons from the Little Red Hen.”

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Juan Salvador Bonifacino will present the Keith Porter Lecture Monday, December 5, at Cell Bio 2022 in Washington, DC.

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The American Society for Cell Biology (ASCB) is excited to honor Don Cleveland with the 2022 E. B. Wilson Medal. Cleveland will present the E.B. Wilson lecture, “Genome instability in cancer: chromothripsis and extrachromosomal DNA,” during Cell Bio 2022 in Washington, DC.

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The American Society for Cell Biology (ASCB) is pleased to announce that Renato J. Aguilera of the University of Texas at El Paso (UTEP) will present the 2022 E.E. Just Lectureship Award. On Sunday, December 4, during Cell Bio 2022 in Washington, DC, he will present the talk “From the Study of DNases to Cancer Research: an Unexpected Scientific Journey.”

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COVID-19 has had a lasting global health impact that continues to challenge the health care system.

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An innovative protocol called PepSeq is changing the way researchers test for contagious diseases—and this knowledge should change the way humanity responds to future pandemics. NAU researcher Jason Ladner and a team of collaborators from TGen published a comprehensive study about PepSeq that lays out the process, the tool and how to interpret the results.

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MYC genes and their proteins play a central role in the emergence and development of almost all cancers.

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About 600 seemingly disparate fungi that never quite found a fit along the fungal family tree have been shown to have a common ancestor, according to a University of Alberta-led research team that used genome sequencing to give these peculiar creatures their own classification home.

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Revealing various signaling pathways in metabolism of oxygen, glucose, lipids, proteins and other nutrients is crucial for better understanding of human physiology and diseases.

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Ulrich Steidl, M.D., Ph.D., an internationally recognized leader in cancer and stem cell biology, has been named the chair of the department of cell biology at Albert Einstein College of Medicine. Dr. Steidl assumes his new position as Arthur Skoultchi, Ph.D., who has led the department with distinction for 24 years, steps down from departmental leadership. Dr. Steidl is currently professor of cell biology, of oncology, and of medicine; interim director of the Ruth L. and David S. Gottesman Institute for Stem Cell Research and Regenerative Medicine; and the Edward P. Evans Endowed Professor for Myelodysplastic Syndromes at Einstein; and deputy director of Montefiore Einstein Cancer Center (MECC) and co-director of MECC’s Blood Cancer Institute.

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The UC San Diego Sanford Stem Cell Institute leads its first space launch, sending stem cells into space aboard the International Space Station. The NASA-partnered study will take advantage of the microgravity environment of space to study accelerated aging in stem cells.

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The principal investigator in the Center for Endocrinology, Diabetes and Metabolism at Children’s Hospital Los Angeles is being honored at WRISG—the Western Region Islet Study Group’s beta cell research meeting. Senta Georgia, PhD, first attended the Western Region Islet Study Group (WRISG) meeting as a graduate student in 2004.

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UC San Diego Alpha Stem Cell Clinic awarded $8M to expand clinical trials of novel stem cell therapies. The CIRM award will advance partnerships between academic and industry experts in San Diego to expedite clinical trials for patients with difficult-to-treat diseases.

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Toxins released by a type of bacteria that cause diarrheal disease hijack cell processes and force important proteins to assemble into “roads to nowhere,” redirecting the proteins away from other jobs that are key to proper cell function, a new study has found.

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More than 20 UT Southwestern Medical Center scientists are among the 2022 Highly Cited Researchers listed in the top 1% of researchers from across the globe

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The goal of the project is to create a membrane-based downstream purification platform for large-scale continuous biomanufacturing of viral vectors and virus-like particles (VLPs).

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For the third time, Sanford Burnham Prebys has been selected by the Frederick National Laboratory for Cancer Research, currently operated by Leidos Biomedical Research, Inc., supporting the NCI Experimental Therapeutics (NExT) Program as a Center for the Chemical Biology Consortium (CBC).

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Newly published study in mice show augmented drug eliminates cancer cells without causing toxicity.

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A gene recognized as the strongest risk factor for Alzheimer’s disease (AD) alters the way cholesterol moves around the brain and as we age, this altered movement likely contributes to loss of learning and memory, a team of researchers from the Icahn School of Medicine at Mount Sinai and the Massachusetts Institute of Technology (MIT) reports.

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In a small study, Johns Hopkins Kimmel Cancer Center researchers successfully trained a machine learning algorithm to predict, in hindsight, which patients with melanoma would respond to treatment and which would not respond.

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Immune checkpoint inhibitors such as Keytruda and Opdivo work by unleashing the immune system’s T cells to attack tumor cells. Their introduction a decade ago marked a major advance in cancer therapy, but only 10% to 30% of treated patients experience long-term improvement. In a paper published online today in The Journal of Clinical Investigation (JCI), scientists at Albert Einstein College of Medicine describe findings that could bolster the effectiveness of immune-checkpoint therapy.

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Hosted by Chulalongkorn University the APRU APEC University Leaders' Forum 2022 is the first post-pandemic in-person APEC meeting held to foster high-level dialogue between CEOs, policy leaders, university presidents, and top researchers. This event begins Nov 15 at 9 PM EST.

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Codonopsis lanceolata, more commonly referred to as “deodeok”, is used as a medicinal herb in South Korea.

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Eyal Gottlieb, Ph.D., has been named MD Anderson's vice president for Research. Gottlieb, an accomplished scientist and leader, will join the institution in January to uphold and expand the institution’s research excellence.