A total of 64 Mercy Medical Center physicians were recognized in Baltimore magazine’s November 2021 “Top Doctors” issue, representing 48 separate specialties
RUDN University discovered the features of liver macrophages activation during its regeneration. In future, it can be used to develop new treatment methods for liver cirrhosis.
Keck Medicine of USC treatment plan significantly reduces hospitalizations and deaths of liver and kidney transplant recipients with COVID-19
Eating mushrooms growing in the wild—lawns, gardens, fields, woods, along roadways and trails— has caused some NJ residents to experience harmful health effects. Since issuing an advisory in August 2021 warning about a dangerous mushroom season, the NJ Poison Control Center has assisted 29 people and four pets with exposures to wild mushrooms. Of those exposed, at least two residents were hospitalized with life-threatening liver toxicity.
Researchers from Sanford Burnham Prebys have discovered a new source of stem cells just outside the liver that could help treat people living with Alagille syndrome, a rare, incurable genetic disorder in which the bile ducts of the liver are absent, leading to severe liver damage and death. The findings, published recently in the journal Hepatology, have extensive biomedical implications for Alagille syndrome and for liver disease in general, including cancer.
This special issue of AJG focuses on emerging concepts in gastroenterology and hepatology and includes updated ACG Clinical Guidelines on the Management of Benign Anorectal Disorders.
Researchers at Johns Hopkins Medicine have found that a drug first developed to treat Alzheimer’s disease, schizophrenia and sickle cell disease reduces obesity and fatty liver in mice and improves their heart function — without changes in food intake or daily activity.
Cesarean birth rates are on the rise, and this is especially true for high-risk pregnant women who have undergone organ transplantation. While cesarean births account for 31% of all deliveries in the United States, the rate of cesarean births for pregnant people with kidney transplants is 62.6% and 44.6% for liver transplants.
Sanford Burnham Prebys professor Peter D. Adams, Ph.D., and Salk Institute professor Gerald Shadel, Ph.D., have been awarded a grant from the NIH’s National Institute on Aging for $13 million, funding a five-year project to explore the connection between aging and liver cancer.
Eating your daily calories within a consistent window of 8-10 hours is a powerful strategy to prevent and manage chronic diseases such as diabetes and heart disease, according to a new manuscript published in the Endocrine Society’s journal, Endocrine Reviews.
In a worldwide pediatric study, researchers from Children’s Hospital Los Angeles show the clear benefit of using living donor liver tissue for transplants.
Study reveals rates of the most common form of liver cancer are rising in rural areas while slowing in urban areas
Expert Q&A: Do breakthrough cases mean we will soon need COVID boosters? The extremely contagious Delta variant continues to spread, prompting mask mandates, proof of vaccination, and other measures. Media invited to ask the experts about these and related topics.
The American Association for the Study of Liver Diseases (AASLD) Foundation, the largest private supporter of liver disease research and training in the United States, today announced its combined investment of over $2.8 million in Research and Career Development Awards, Abstract Awards, and its Emerging Liver Scholars (ELS) Program.
In a new National Institutes of Health (NIH) initiative, the University of Miami Miller School of Medicine was selected for a nationwide Liver Cirrhosis Network. Researchers in the network’s 10 academic medical centers will share patient data and launch clinical trials of a class of medications that could prevent progression of the disease, which causes irreversible scarring of the liver, and complications such as liver cancer.
Time-restricted eating (TRE), a dietary regimen that restricts eating to specific hours, has garnered increased attention in weight-loss circles.
A new study from Keck Medicine of USC reveals that Black recipients of liver transplants have lower post-transplant survival rates than white or Hispanic patients
The August issue of The American Journal of Gastroenterology includes clinical discussions of diet-associated NAFLD risk and increased risk of mortality from COVID-19 among PPI users. In addition, this issue features clinical research and reviews on IBS, gender barriers for CRC screening, hepatitis C, eosinophilic esophagitis, and more.
Researchers at Wake Forest School of Medicine have shown that a targeted therapy using non-thermal radio waves is safe to use in the treatment of hepatocellular carcinoma (HCC), the most common type of liver cancer. The therapy also showed a benefit in overall survival. The study findings appear online in 4Open, a journal published by EDP Sciences.
Mount Sinai researchers have found evidence for the first time that World Trade Center responders had a higher likelihood of developing liver disease if they arrived at the site right after the attacks as opposed to working at Ground Zero later in the rescue and recovery efforts. Their study links the increase in liver disease risk to the quantity of toxic dust the workers were exposed to, which was greatest immediately after the September 11, 2001, attacks.
A Wayne State University School of Medicine researcher has been awarded a $2.3 million grant by the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health, to support research in circadian RNA modification in metabolic disease.
A combination of the kinase-inhibitor drug cabozantinib and the immunotherapy drug nivolumab can make curative surgery possible in some liver cancer patients who would normally not be considered surgery candidates.
The body’s so-called good cholesterol may be even better than we realize. New research from Washington University School of Medicine in St. Louis suggests that one type of high-density lipoprotein (HDL) has a previously unknown role in protecting the liver from injury. This HDL protects the liver by blocking inflammatory signals produced by common gut bacteria.
A chemical modification that occurs in some RNA molecules as they carry genetic instructions from DNA to cells’ protein-making machinery may offer protection against non-alcoholic fatty liver, a condition that results from a build-up of fat in the liver and can lead to advanced liver disease, according to a new study by UCLA researchers. The study, conducted in mice, also suggests that this modification — known as m6A, in which a methyl group attaches to an RNA chain — may occur at a different rate in females than it does in males, potentially explaining why females tend to have higher fat content in the liver. The researchers found that without the m6A modification, differences in liver fat content between the sexes were reduced dramatically.
A study shows for the first time that people with cirrhosis who receive mRNA COVID-19 vaccination gain important protection against more serious outcomes like hospitalization and death. At the same time, however, the vaccines offer less protection against SARS-CoV-2 infection and take longer to take effect in this population.
UC San Diego researchers discovered that immunotoxins targeting the protein mesothelin prevent liver cells from producing collagen, a precursor to fibrosis and cirrhosis, in mouse models of human disease.
Drinking coffee that is caffeinated (ground or instant) or decaffeinated is associated with a reduced risk of developing chronic liver disease and related liver conditions, according to a study published in the open access journal BMC Public Health.
In a subset of patients with partial lipodystrophy and/or NASH, the hormone leptin can be leveraged as a therapeutic agent to move fat out of the liver.
DALLAS – June 4, 2021 – Increasing a protein concentrated in brown fat appears to lower blood sugar, promote insulin sensitivity, and protect against fatty liver disease by remodeling white fat to a healthier state, a new study led by UT Southwestern scientists suggests. The finding, published online in Nature Communications, could eventually lead to new solutions for patients with diabetes and related conditions.
Researchers at University of California San Diego School of Medicine found in a mouse model that when fed a Western diet rich in calories, fat and cholesterol, the mice progressively became obese, diabetic and developed NASH, which progressed to HCC, chronic kidney and cardiovascular disease.
Research suggests that women who have weight loss surgery need to reduce the amount of fat they eat after surgery to reap the full benefit of the procedure and protect their liver function. The study is published ahead of print in the American Journal of Physiology-Endocrinology and Metabolism.
A new multi-institution study led by a team of researchers at the David Geffen School of Medicine demonstrated that blocking a protein called ABCB10 in liver cells protects against high blood sugar and fatty liver disease in obese mice. ABCB10 activity also prompted insulin resistance in human liver cells.
newly issued updates to ACG Clinical Guidelines on Upper Gastrointestinal and Ulcer Bleeding and Diagnosis and Management of Idiosyncratic Drug-Induced Liver Injury. In addition to the guidelines, this issue features clinical research on esophageal cancer, obesity, telemedicine, celiac disease, Crohn’s disease, and more.
Recent years have brought increased attention to the lasting effects of chemicals we unwittingly inhale, touch and ingest while going about our daily lives. The Experimental Biology (EB) 2021 meeting features the latest research on how environmental exposures affect health.
New insights into how fetal and adult liver cells differ could be used to help make liver cell transplants successful long term. Transplanting functioning liver cells into a patient’s liver can help replace liver function that is impaired due to disease.
Thousands of livers donated for transplantation are discarded or turned down every year due to concerns about organ quality and function. New insights into why these organs are considered unusable and how they function during external perfusion could help save lives by greatly increasing the number of livers that are transplantable.
Reporters are invited to join a live Q&A discussion of exciting research announcements at the forefront of the life sciences during a virtual press conference for the Experimental Biology (EB) 2021 meeting. The press conference will be held online from 1–1:45 p.m. EDT on Monday, April 26, 2021 (RSVP by Friday, April 23).
Patients with high levels of antibodies face major challenges getting a transplant. These highly sensitized patients have a higher risk of death while waiting for suitable organs. But there is new hope for highly sensitized patients in need of a combined heart and liver transplant, thanks to an innovative surgical approach at Mayo Clinic.
NYU Langone Health will expand colorectal cancer screenings to address disease disparities in underserved communities with a $2.2 million grant from the Steven & Alexandra Cohen Foundation.
Bariatric surgery can significantly reduce the risk of cancer—and especially obesity-related cancers—by as much as half in certain individuals, according to a study by researchers at Rutgers Robert Wood Johnson Medical School’s Center for Liver Diseases and Liver Masses.
Immunotherapy is not only significantly less effective in liver cancer patients who previously had a liver disease called non-alcoholic steatohepatitis (NASH), but actually appears to fuel tumor growth, according to a Mount Sinai study published in Nature in March. NASH affects as many as 40 million people worldwide and is associated with obesity and diabetes.
Sugar is added to many common foodstuffs, and people in Switzerland consume more than 100 grams of it every day.
Scientists developed a highly efficient, targeted method for delivering gene editing machinery to specific tissues and organs, demonstrating the treatment of high cholesterol by targeting genes in the liver of mice, reducing cholesterol for over 3 months (and potentially more) with one treatment
While the amazing regenerative power of the liver has been known since ancient times, the cells responsible for maintaining and replenishing the liver have remained a mystery. Now, research from the Children’s Medical Center Research Institute at UT Southwestern (CRI) has identified the cells responsible for liver maintenance and regeneration while also pinpointing where they reside in the liver.
Early detection could reduce the number of African Americans dying from liver cancer, but current screening guidelines may not find cancer soon enough in this community, according to a study published in Cancer in February.
Un equipo de Mayo Clinic, dirigido por Dr. Rahmi Oklu, en colaboración con el Dr. Samir Mitragotri de la Universidad de Harvard, informó sobre el desarrollo de una nueva fórmula de líquido iónico que, a nivel del laboratorio, eliminó células cancerígenas y permitió repartir uniformemente el fármaco quimioterapéutico dentro de tumores hepáticos y otros tumores sólidos.
A Mayo Clinic team, led by Rahmi Oklu, M.D., Ph.D., a vascular and interventional radiologist at Mayo Clinic, in collaboration with Samir Mitragotri, Ph.D., of Harvard University, report the development of a new ionic liquid formulation that killed cancer cells and allowed uniform distribution of a chemotherapy drug into liver tumors and other solid tumors in the lab.
A clinical study led by Dr. Jordan Feld, a liver specialist at Toronto Centre for Liver Disease, University Health Network (UHN), showed an experimental antiviral drug can significantly speed up recovery for COVID-19 outpatients – patients who do not need to be hospitalized. This could become an important intervention to treat infected patients and help curb community spread, while COVID-19 vaccines are rolled out this year.
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right