A so-called pathological protein long associated with Parkinson’s disease has been found in a new study to trigger cells to increase protein synthesis, an event that eventually kills the subset of brain cells that die off in this neurodegenerative condition.
When Voyager 2 flew past Uranus in 1986, the planet appeared to be a nearly featureless, solid blue ball. Now, Webb shows us an infrared view that is much more dynamic and intriguing.
New research has revealed that Rembrandt impregnated the canvas for his famous 1642 militia painting ‘The Night Watch’ with a lead-containing substance even before applying the first ground layer.
Nature Communications today published research by an international team from Wits and ICFO- The Institute of Photonic Sciences, which demonstrates the teleportation-like transport of “patterns” of light – this is the first approach that can transport images across a network without physically sending the image, and a crucial step towards realising a quantum network for high-dimensional entangled states.
Among many parents’ top resolutions for the New Year: More patience, less time on phones, better consistency with discipline and healthier family habits.
An artificial intelligence (AI) tool developed by investigators at the Smidt Heart Institute at Cedars-Sinai and colleagues at two other institutions accurately predicted how patients would fare after surgeries and procedures.
UCL researchers have developed a new gene therapy to cure a devastating form of childhood epilepsy, which a new study shows can significantly reduce seizures in mice
New research from Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care System comparing the viruses that cause the flu and COVID-19 shows that people hospitalized with seasonal influenza also can suffer long-term, negative health effects, especially involving their lungs and airways. The study also found that in the 18 months after infection, patients hospitalized for either COVID-19 or seasonal influenza faced an increased risk of death, hospital readmission, and other health problems.
University of Wisconsin–Madison engineers have used a spray coating technology to produce a new workhorse material that can withstand the harsh conditions inside a fusion reactor.
Using cells from kidney biopsies, Johns Hopkins Medicine, researchers report progress in the search for more accurate and easier-to-obtain markers to help predict, manage and assess treatment of acute kidney injury (AKI).
• Researchers at IRB Barcelona reveal the pivotal role of iron accumulation in the development of fibrotic diseases and propose that iron detection via MRI can serve to diagnose fibrosis. • Fibrotic diseases account for 45% of all mortality in developed countries. • Published in Nature Metabolism, the study points to new therapeutic opportunities that target iron.
People who are very sleepy during the day, despite a good night’s rest, may have a sleep disorder called idiopathic hypersomnia. New research has found this neurologic disorder may not be as rare as once thought.
People who have very irregular sleep patterns may have a higher risk of dementia than those who have more regular sleep patterns, according to new research published in the December 13, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Flat-faced dogs' popularity comes at a high cost in terms of health: shortened skulls are associated with deteriorative brain morphology changes, breathing difficulties and sleep problems.
Observations in mice hint at role of daydreams in remodeling the brain
Brown dwarfs are sometimes called failed stars, since they form like stars through gravitational collapse, but never gain enough mass to ignite nuclear fusion.
A young Rottweiler has been given a new lease on life following innovative, ground-breaking prosthetic surgery to make him fully mobile again. Three-year-old Covid is on his way to recovery after successful surgery that’s allowed the attachment of an artificial foot to give him maximum quality of life.
The targeted therapy combination of ibrutinib and venetoclax significantly improved progression-free survival (PFS) and achieved an overall remission rate in 82% of patients with relapsed/refractory mantle cell lymphoma (MCL), according to researchers at The University of Texas MD Anderson Cancer Center. Results from the Phase III SYMPATICO trial were presented at the 2023 American Society of Hematology (ASH) Annual Meeting.
Alcohol use on certain special occasions may contribute to harsher parenting by mothers, according to an innovative study.
Researchers conducting a Phase 2 clinical trial at Sylvester Comprehensive Cancer Center say a new combination of antibody therapies produced a ‘surprisingly high’ response rate in patients with high-risk follicular lymphoma, a type of non-Hodgkin lymphoma.
In a study led by researchers at Sylvester Comprehensive Cancer Center, patients recently diagnosed with a common and aggressive form of acute myeloid leukemia reported having improved quality of life when a newly approved drug was part of the treatment plan.
Intimate partner violence is widespread and can have severe physical and psychological health repercussions, but there is a shortage of research on reliable predictors of abuse before it occurs. New research, published in Social Psychological and Personality Science, identifies several warning signs that preceded and predicted intimate partner violence.
Objects in space reveal different aspects of their composition and behavior at different wavelengths of light. Supernova remnant Cassiopeia A (Cas A) is one of the most well-studied objects in the Milky Way across the wavelength spectrum.
Combining the JAK inhibitor ruxolitinib with the BCL-xL inhibitor navitoclax was twice as effective in reducing enlarged spleens – a major indicator of clinical improvement – compared with standard-of-care ruxolitinib monotherapy for adult patients with intermediate or high-risk myelofibrosis, a rare bone marrow cancer, according to results of the Phase III TRANSFORM-1 trial reported by researchers from The University of Texas MD Anderson Cancer Center.
A new study from researchers with Sylvester Comprehensive Cancer Center and collaborating organizations provides insight into the underlying mechanisms of gene mutations commonly seen in patients with myelodysplastic syndromes (MDS) and other myeloid neoplasms.
The High Energy Physics Advisory Panel (HEPAP) to the High Energy Physics program of the Office of Science of the U.S. Department of Energy and the National Science Foundation’s Division of Physics has released a new Particle Physics Project Prioritization Panel (P5) report, which outlines particle physicists’ recommendations for research priorities in the field.
One to two weeks after contracting COVID, the SARS-CoV-2 virus generally becomes undetectable in the upper respiratory tract. But does that mean that it is no longer present in the body? To find out, a team from the Institut Pasteur specialized in HIV, in collaboration with a French public research institute, the Alternative Energies and Atomic Energy Commission (CEA), conducted a study on lung cells in an animal model.
The elements above iron on the periodic table are thought to be created in cataclysmic explosions like the merger of two neutron stars or in rare classes of supernovae. New research suggests fission may operate in the cosmos during the creation of the heavy elements. Combing through data on a variety of elements that reside in very old stars, researchers have found a potential signature of fission, indicating that nature is likely to produce superheavy nuclei beyond the heaviest elements on the periodic table.
The Department of Energy’s Oak Ridge National Laboratory and Caterpillar Inc. have entered into a cooperative research and development agreement, or CRADA, to investigate using methanol as an alternative fuel source for four-stroke internal combustion marine engines. The collaboration supports efforts to decarbonize the marine industry, a hard-to-electrify transportation sector.
A new Cedars-Sinai study might have cracked the mystery surrounding the cause of a specific type of back pain.
Comparing PET scans of more than 90 adults with and without mild cognitive impairment (MCI), Johns Hopkins Medicine researchers say relatively lower levels of the so-called “happiness” chemical, serotonin, in parts of the brain of those with MCI may play a role in memory problems including Alzheimer’s disease.
What can you do about that ache in your throat when you have a cold? A Penn State Heath family physician offers five remedies.
Ovarian cancer is the deadliest cancer of the female reproductive system, and there is no screening test that can help with early detection. Ultrasound imaging, the standard of care used to determine whether lesions are cancerous or benign, is not always accurate, leading some patients to have the ovaries removed unnecessarily.
Scientists from Stanford University and the Department of Energy’s Oak Ridge National Laboratory are turning air into fertilizer without leaving a carbon footprint.
Phoebe Peng, an Engineering Honours student at the University of Sydney, is researching ways to allow people with low vision and blindness to play pingpong using sound. The process uses neuromorphic cameras and an array of loudspeakers, designed to allow players to track the ball and movements based on sound. Using two perfectly positioned cameras, Peng could identify and track a ball in 3D in real time. She then fed that data into an algorithm controlling loudspeakers along the sides of the table, which created a sound field matching the position of the ball.
In some diseases, the underlying processes can start years before a diagnosis is made. A new study finds that people who later develop multiple sclerosis (MS) are more likely to have conditions like depression, constipation and urinary tract infections five years before their MS diagnosis than people who do not develop MS.
Researchers from Shanghai Jiao Tong University have developed a promising new solar-powered atmospheric water harvesting technology that could help provide enough drinking water for people to survive in difficult, dryland areas: They synthesized a super hygroscopic gel capable of absorbing and retaining an unparalleled amount of water. .
A study of more than 50 babies through 2 yeard old in Africa, Asia, North America and South America has added substantially to evidence that giving antiretroviral therapy (ART) to newborns with HIV within the first days — rather than within weeks or months — of life can safely suppress amounts of HIV in the blood to undetectable levels. Findings of the study, which was co-led by Johns Hopkins Children’s Center physician-scientist and researcher Deborah Persaud, M.D., and sponsored by the National Institutes of Health (NIH) and the International Maternal Pediatric Adolescent AIDS Clinical Trials Network, were published Dec. 4 in the journal The Lancet HIV.
A new PNAS Nexus study led by scientists from the USDA Agricultural Research Service (USDA-ARS) and the University of Illinois Urbana-Champaign takes a retrospective look at glyphosate efficacy after tolerant crops were commercialized.
A new tool developed by researchers from Binghamton University, State University of New York will make it easier for clinicians and researchers to measure digital media addiction as new technologies emerge.
Telemedicine visits for patients with hyperlipidemia — an excess of cholesterol or fats in the blood — experienced similar positive health benefits compared to those who had in-person visits, a study finds. Researchers say telemedicine offers additional options to access treatment that could reduce the risk of cardiovascular disease.
Parag Chitnis of George Mason University led a team that developed a wearable ultrasound system that can produce clinically relevant information about muscle function during dynamic physical activity. The system uses a patented approach that uses long-duration chirps and ultrasound sensing, and it allowed the team to design a simpler, cheaper system that could be miniaturized and powered by batteries. The result is an ultrasound monitor with a small, portable form factor that can be attached to a patient.
Two new studies led by researchers from the UCLA Jonsson Comprehensive Cancer Center give insight into how cells use energy to influence the way prostate tumors survive and grow — advancements that can help explain why some prostate cancers become resistant to hormone therapy, the most commonly used treatment for men with advanced stages of the disease.
About 20% of patients whose medical records showed them as being alive were in fact deceased according to California data.
Many of the most potent human oncoproteins belong to a class of proteins called transcription factors, but designing small molecule drugs that target transcription factors is a major challenge.
The sound a disc makes while soaring through the air is full of information about how fast the disc is flying and how quickly it spins.
Darcy Dunn-Lawless, a doctoral student at the University of Oxford, is investigating the potential of a painless, needle-free vaccine delivery by ultrasound. The method uses cavitation, which is the formation and popping of bubbles in response to a sound wave. Though initial in vivo tests reported 700 times fewer vaccine molecules were delivered by the cavitation approach compared to conventional injection, the cavitation approach produced a higher immune response. The researchers theorize this could be due to the immune-rich skin the ultrasonic delivery targets. The result is a more efficient vaccine that could help reduce costs and increase efficacy.
A new study from researchers at Wake Forest University School of Medicine shows that dopamine release in the human brain plays a crucial role in encoding both reward and punishment prediction errors.
Atmospheric scientists at UAlbany and China’s Jiangsu Meteorological Observatory recently co-published a new paper in AGU’s Geophysical Research Letters that finds unstable atmospheric conditions have significantly increased over the last several decades.
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