A new study offers strong evidence that kids who use e-cigarettes are more likely to take up smoking or smokeless tobacco, researchers say. Teen boys who vaped were almost three times as likely to start smoking as other teen boys with similar risk profiles and more than two times as likely to try smokeless tobacco, the study from The Ohio State University found.
New study in mice finds that a high-fat diet allows cancer cells to outcompete immune cells for fuel, impairing immune function and accelerating tumor growth. Findings suggest new strategies to target cancer metabolism, improve immunotherapies.
UCLA researchers studying cancer evolution have created a framework to help determine which tool combinations are best for pinpointing the exact timing of DNA mutations in cancer genomes.
A study led by The University of Texas MD Anderson Cancer Center showed that first-line treatment with a regimen of chemotherapy combined with the monoclonal antibody blinatumomab resulted in increased survival and achieved a high rate of measurable residual disease (MRD) negativity for patients who were newly diagnosed with a high-risk form of acute lymphoblastic leukemia (ALL) known as Philadelphia chromosome-negative B-cell ALL (Ph-negative B-ALL).
Researchers from The University of Kansas Cancer Center are involved in the presentation of nearly 50 research studies at the 62nd American Society of Hematology (ASH) Annual Meeting.
The American Society of Hematology (ASH), is the world’s largest professional society with a focus on the causes and treatment of blood disorders. Experts from Rutgers Cancer Institute of New Jersey will be presenting a variety of key hematology data at the 62nd American Society of Hematology Annual Meeting. This includes 22 scheduled presentations, including 10 oral presentations examining several types of blood cancers including leukemia, lymphoma, and myeloma.
Story of a man who celebrated his five-year survival with GBM. He received 5-ALA prior to surgery, which helps the surgeon see more of the tumor for removal, and he was in a Phase 1 clinical trial.
Craig Jordan, PhD, has spent more than 20 years developing better treatments for acute myeloid leukemia (AML), a rapidly progressing cancer of the blood and bone marrow that can spread to other parts of the body, including the lymph nodes, liver, spleen and central nervous system.
Researchers at The University of Texas MD Anderson Cancer Center have developed a novel targeted therapy, called POMHEX, which blocks critical metabolic pathways in cancer cells with specific genetic defects. Preclinical studies found the small-molecule enolase inhibitor to be effective in killing brain cancer cells that were missing ENO1, one of two genes encoding the enolase enzyme.
In a study on human ovarian cancer cells transplanted into mice, Harvard Medical School researchers discovered a transient, cooperative interaction between cell subpopulations that allows otherwise nonmetastatic tumor cells to become aggressive and spread.
School of Medicine awarded $2.6M; receives two of 13 grants nationally
Rutgers Cancer Institute of New Jersey expert addresses what you should know about pancreatic cancer including risks, symptoms and treatment.
Researchers at the UCLA Jonsson Comprehensive Cancer Center found patients with a particular type of human leukocyte antigen (HLA), a protein scaffold involved in presenting pieces of proteins described as peptides to the immune system, were particularly likely to benefit from immunotherapy.
A team of scientists from Albert Einstein College of Medicine has received a five-year, $4.9 million grant from the National Institutes of Health (NIH) to establish a research center to investigate HIV- and human papillomavirus (HPV)-related cancers in Africa.
Moffitt Cancer Center researchers are working to improve CAR T responses and make those responses more long-lasting for patients. In a new article published in Cancer Immunology Research, the team shares its findings, which show alterations to a specific domain of the chimeric antigen receptor enhances CAR T-cell activity and survival.
An Indiana University Melvin and Bren Simon Comprehensive Cancer Center researcher has been awarded a five-year, $2.9 million grant from the National Cancer Institute to develop a drug that could make radiation therapy far more effective.
Early and repeated exposures to diagnostic imaging, such as X-rays and CT scans, may increase the risk of testicular cancer.
CHICAGO (October 30, 2020): Colon cancer patients achieve better five-year survival rates when the surgeons who treat them are rated as highly skilled, according to findings from what authors say is the first study to link a surgeon’s technical skills with improved long-term clinical outcomes. The study is published online in JAMA Oncology and virtually presented as part of the American College of Surgeons Commission on Cancer’s Annual Research Paper Competition.
Four MSK researchers out of 15 winners nationwide were named recipients of the prestigious award. They will each receive a grant of up to $600,000 per year for seven years to support their research in cancer.
Researchers at the Johns Hopkins Bloomberg School of Public Health and Johns Hopkins University School of Medicine have been jointly awarded a major grant from the National Cancer Institute, part of the National Institutes of Health, to set up a center for research on the human serological immune response to SARS-CoV-2, the coronavirus that causes COVID-19.
A Morgridge imaging study of macrophages — immune cells that are important to human health, but paradoxically can help some cancers grow and spread — is offering better ways to understand these cells and target them with immunotherapies.
A new analysis highlights the diversity of immune response in pancreatic cancer, and points toward the need for treatments tailored to individual patients.
GRAND RAPIDS, Mich. (Oct. 22, 2020) — Scientists have developed a simple, experimental blood test that distinguishes pancreatic cancers that respond to treatment from those that do not. This critical distinction could one day guide therapeutic decisions and spare patients with resistant cancers from undergoing unnecessary treatments with challenging side effects.
In a new article published in the journal Nature Communications, Moffitt Cancer Center researchers describe how the protein TAp63 controls levels of RNA molecules, which subsequently connects the activities of p53 and AKT to promote disease progression.
Researchers have used insight from a comprehensive genomic analysis of neuroblastoma to learn about the process driving one of the most common childhood solid tumors.
The Rutgers Youth Enjoy Science (RUYES) program, funded by the National Cancer Institute, will engage underrepresented minority undergraduate and high school students in cutting-edge cancer research, curriculum support, and professional development activities.
Cedars-Sinai has been awarded a five-year, $8.3 million grant by the National Cancer Institute (NCI) to study the diversity and determinants of the immune-inflammatory response to SARS-CoV-2, the virus that causes COVID-19 (coronavirus).
Researchers with the Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center have secured $4 million in funding from the National Institutes of Health (NIH)/National Cancer Institute (NCI) to establish an HIV-associated Malignancy Research Center focused on lung cancer in East Africa.
Researchers from the Icahn School of Medicine at Mount Sinai will receive more than $7.3 million from the National Cancer Institute (NCI) as part of the NCI’s new Serological Sciences Network (SeroNet), one of the largest coordinated national efforts to study immunology and SARS-CoV-2, the virus that causes COVID-19. Mount Sinai was selected as one of only four Capacity Building Centers and one of eight Centers of Excellence as part of this new network.
Indica Labs, a leading provider of computational pathology software and services, are pleased to announce the formal launch of an enterprise-wide, cloud-based deployment of Indica Labs' software within the National Cancer Institute (NCI), including HALO®, HALO AI, HALO Link and HALO AP.
In a new study, infectious disease researchers show that HIV viremia isn’t always nonadherence to medication or resistance to the drugs. Instead, the patients are victims of what the scientists have dubbed “repliclones” – large clones of HIV-infected cells that produce infectious virus particles.
In one year, The University of Kansas Cancer Center will submit its application to renew its prestigious National Cancer Institute (NCI) designation in the hopes of attaining “comprehensive” status, the NCI’s highest ranking.
The University of Kansas Cancer Center’s status as a community site of the National Cancer Institute’s Community Oncology Research Program has been renewed after exceeding clinical trial accrual goals by more than 22% in its first year.
The National Cancer Institute award provides extended support for researchers to pursue projects with groundbreaking cancer research potential
Mesothelioma is a deadly cancer mainly caused by exposure to asbestos fibers.
The Tisch Cancer Institute at Mount Sinai (TCI) has been awarded $13 million as part of the renewal of its National Cancer Institute Cancer Center Designation, a prestigious distinction that is based on scientific excellence, robust clinical research, and beneficial community impact. The National Cancer Institute rated TCI’s application as “outstanding.”
A team led by researchers from Case Western Reserve University School of Medicine and Cleveland Clinic Lerner Research Institute has secured $10.4 million over five years from the National Institutes of Health/National Cancer Institute to explore at the molecular level the differences in glioblastoma between males and females.
DALLAS – Sept. 17, 2020 – When used to manage infections, the drug itraconazole is generally given at a single, fixed dose to all patients. But determining the correct dosage of the drug to help treat cancer isn’t that simple, new research by UT Southwestern suggests.
African American men have the lowest five-year survival rate for colorectal cancer (CRC) out of any other racial group. A major factor is low adherence to recommended early detection screening. Yet published research on effective strategies to increase screening for this group specifically are minimal. These findings were published today in PLOS ONE.
NIH has awarded seven contracts to companies and academic institutions to develop digital health solutions that help address the COVID-19 pandemic.
Newly published research has reversed our understanding of an aspect of kidney tumor growth. Researchers at Huntsman Cancer Institute at the University of Utah discovered that two key proteins have opposite roles than what was previously believed.
Scientists at the College of Veterinary Medicine have collaborated on a study that pinpoints which specific genes drive – or delay – High-grade serious ovarian carcinoma.
It’s clear that radiation therapy, or radiotherapy, an approach used to treat cancer since the early 20th century, can be an effective companion to newer, immune-stimulating approaches known as immunotherapy. Research from a team from Roswell Park Comprehensive Cancer Center explains how radiation helps boost the immune system’s ability to fight cancer in combination with immune checkpoint inhibitors — and provides new evidence that the timing of these therapies can make a big difference in how effectively they work together.
If cancer is a series of puzzles, a new study pieces together how several of those puzzles connect to form a bigger picture. A connection between three separate puzzles suggests targeting the amino acid methionine transporter in tumor cells could make immunotherapy effective against more cancers.
In a new article published in the Journal of Investigative Dermatology, Moffitt researchers identify erythropoietin-producing hepatocellular receptor A2 (EphA2) as a driver of metastasis and BRAF-MEK inhibitor resistance in melanoma.
In laboratory studies, Johns Hopkins Kimmel Cancer Center and Johns Hopkins University researchers observed a key step in how cancer cells may spread from a primary tumor to a distant site within the body, a process known as metastasis.
The Herbert Irving Comprehensive Cancer Center has been redesignated as a Comprehensive Cancer Center by the NCI, the federal government’s principal agency for cancer research, care and training.
Patients who develop cytomegalovirus infections after allogeneic stem cell transplantation may be able to develop an immunity against the virus, strengthen their immune system and reduce reliance on strong antiviral medications, a team from Roswell Park reports in the journal Biology of Blood and Marrow Transplantation.
Splitting one type of cancer drug in half and delivering the pieces separately to cancer cells could reduce life-threatening side effects and protect healthy, non-cancerous cells, a new study suggests.
In a breakthrough study, researchers at Children’s Hospital of Philadelphia (CHOP) have shown that an enhanced treatment developed in their lab leads to long-term remissions in 80% to 100% of mice with drug-resistant or high-risk solid tumors. The research, which could soon lead to clinical trials, is described in Cancer Research, a journal of the American Association for Cancer Research.
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