Connecting Research and Experts with Journalists

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A Cleveland Clinic-led research collaboration between Timothy Chan, MD, PhD, Chair of Cleveland Clinic’s Global Center for Immunotherapy, and Bristol Myers Squibb has published the most comprehensive overview to date of how our immune system reshapes tumor architecture in response to immune checkpoint therapy. The eight-year study, published in Nature Medicine, outlines how cancer immunotherapy induces tumor recognition through neoantigens to reshape the tumor ecosystem.

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How do consumers feel about robots generating emotionally charged marketing content? That’s the question a New York Institute of Technology professor raises in a new Journal of Business Research study.

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Cancer cells frequently overhaul their surroundings, making tumors stiffer than nearby healthy tissue. While tumor stiffening makes some cancers easier to detect — this is why physicians feel for hard lumps in the body — it can also ramp up tumor growth and drug resistance. New research suggests that these detrimental changes are not set in stone, however.

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The complex shape of respiratory syncytial virus is one hurdle limiting the development of treatments for an infection that leads to hospitalization or worse for hundreds of thousands of people in the United States each year, according to the Centers for Disease Control and Prevention. New images of the virus from researchers at the University of Wisconsin–Madison may hold the key to preventing or slowing RSV infections.

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New research from Christina Bambrick, the Filip Family Assistant Professor of Political Science at the University of Notre Dame, explores the nonconventional idea that each of us, as private citizens, may be responsible for upholding the constitutional rights of our fellow citizens. She examines constitutional politics across the globe to explore these different approaches to balancing rights and responsibilities in a democratic society.

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Chronic kidney disease is a progressive condition that affects more than 10% of the general population worldwide, amounting to 800 million individuals.1 Glomerular diseases (GD), excluding diabetic nephropathy, account for approximately 25% of the cases of kidney diseases worldwide.2 Given the magnitude of long-term morbidity from GD— particularly the frequent manifestation in younger patients—diagnosing it efficiently and optimizing management to control diseases and prevent progressive kidney diseases is paramount.

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A sociological investigation estimated the effects of Alaska’s universal cash transfer program on newborn health outcomes using data spanning 28 years.

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Using a sophisticated brain-imaging system, neuroscientists at Johns Hopkins Medicine say they have successfully reactivated a specific memory circuit in mice, causing them to seek out shelter when no shelter is actually present.

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See how structures of Fanzor2, a relation of the transposon family TnpB, show how the protein can be used in genome engineering technology like CRISPR-Cas9.

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More than 2 million people were without power in the Southwest United States today due to the aftermath of Hurricane Helene. Research by a team of scientists at the George Washington University... ...