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5-Sep-2024 3:35 PM EDT
100x Improvement in Sight Seen After Gene Therapy Trial
Perelman School of Medicine at the University of Pennsylvania

The vision of people with a rare inherited condition that causes them to lose much of their sight early in childhood was 100 times better after they received gene therapy to address the genetic mutation causing it. Some patients even experienced a 10,000-fold improvement in their vision after receiving the highest dose of the therapy, according to researchers from the Perelman School of Medicine at the University of Pennsylvania who co-led the clinical trial published in The Lancet.

Not for public release

This news release is embargoed until 3-Sep-2024 11:00 AM EDT Released to reporters: 29-Aug-2024 11:00 AM EDT

A reporter's PressPass is required to access this story until the embargo expires on 3-Sep-2024 11:00 AM EDT The Newswise PressPass gives verified journalists access to embargoed stories. Please log in to complete a presspass application. If you have not yet registered, please Register. When you fill out the registration form, please identify yourself as a reporter in order to advance to the presspass application form.

28-Aug-2024 4:05 PM EDT
Combo immunotherapy produces distinct waves of cancer-fighting T cells with each dose
Perelman School of Medicine at the University of Pennsylvania

A new tool for monitoring immune health patterns over time reveals how a pair of checkpoint inhibitor therapies works together to recruit new cancer-fighting T cells with every infusion.

Released: 28-Aug-2024 1:05 PM EDT
Keeping calm in case of catastrophe
Perelman School of Medicine at the University of Pennsylvania

The small but dedicated Hospital Emergency Response Team works year-round to imagine and prepare for major crises that could disrupt patient care.

Released: 28-Aug-2024 1:05 PM EDT
Breaking through the mysteries of predicting coma recovery
Perelman School of Medicine at the University of Pennsylvania

Predicting a patient’s recovery from a coma has profound implications. Neurologist David Fischer, MD, is building the infrastructure to get it right.

Released: 21-Aug-2024 10:05 AM EDT
Penn Medicine and Parker Institute renew alliance to continue advancing groundbreaking cancer immunotherapy research
Perelman School of Medicine at the University of Pennsylvania

The University of Pennsylvania and the Parker Institute for Cancer Immunotherapy (PICI) have renewed their collaboration to advance cancer immunotherapy research at Penn Medicine’s Abramson Cancer Center (ACC).

Released: 29-Jul-2024 2:05 PM EDT
To Get Drivers to Put Down Their Phones, Make it a Game
Perelman School of Medicine at the University of Pennsylvania

A large trial of strategies to reduce distracted driving showed that those that were “gamified” yielded a lasting reduction in handheld phone usage while driving

Released: 25-Jul-2024 12:05 PM EDT
Penn Researchers Reveal How a Bacterium Supports Healing of Chronic Diabetic Wounds
Perelman School of Medicine at the University of Pennsylvania

There are many important reasons for keeping cuts and sores clean, but new research from the Perelman School of Medicine at the University of Pennsylvania shows that a certain can facilitate healing of hard-to-treat wounds among people with diabetes.

Released: 22-Jul-2024 9:05 AM EDT
Knockout of CD5 on CAR T Cells Boosts Anti-Tumor Efficacy
Perelman School of Medicine at the University of Pennsylvania

The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by using CRISPR-Cas9 technology to knock out the gene for CD5, a protein found on the surface of T cells, according to a preclinical study from investigators at the University of Pennsylvania’s Perelman School of Medicine and Abramson Cancer Center.

Not for public release

This news release is embargoed until 18-Jul-2024 2:00 PM EDT Released to reporters: 18-Jul-2024 9:05 AM EDT

A reporter's PressPass is required to access this story until the embargo expires on 18-Jul-2024 2:00 PM EDT The Newswise PressPass gives verified journalists access to embargoed stories. Please log in to complete a presspass application. If you have not yet registered, please Register. When you fill out the registration form, please identify yourself as a reporter in order to advance to the presspass application form.

9-Jul-2024 11:05 AM EDT
When there’s money to lose, phone usage while driving drops
Perelman School of Medicine at the University of Pennsylvania

Researchers discovered that feedback plus cash incentives designed with insights from behavioral science reduces phone use while driving

1-Jul-2024 8:05 AM EDT
New form of repetitive magnetic brain stimulation reduces treatment time for bipolar disorder
Perelman School of Medicine at the University of Pennsylvania

A potential new treatment for bipolar disorder (BP) that significantly shortens treatment time has emerged, following a randomized clinical trial using accelerated intermittent theta burst stimulation (aiTBS). While current theta burst stimulation (TBS) treatments can take between four and six weeks to administer, this new technique reduces treatment to five days.

Released: 28-Jun-2024 12:05 PM EDT
Penn researchers will investigate link between TBI and dementia with $10M NIH grant
Perelman School of Medicine at the University of Pennsylvania

An international team of researchers led by Penn Medicine will investigate the link between traumatic brain injuries (TBI) and Alzheimer’s disease and related dementias (ADRD) over the next five years with a $10 million grant from the National Institute of Neurological Disorders and Stroke (NINDS).

Not for public release

This news release is embargoed until 25-Jun-2024 11:00 AM EDT Released to reporters: 24-Jun-2024 9:00 AM EDT

A reporter's PressPass is required to access this story until the embargo expires on 25-Jun-2024 11:00 AM EDT The Newswise PressPass gives verified journalists access to embargoed stories. Please log in to complete a presspass application. If you have not yet registered, please Register. When you fill out the registration form, please identify yourself as a reporter in order to advance to the presspass application form.

Released: 18-Jun-2024 10:05 AM EDT
Slowing inflammation may boost immunotherapy’s effectiveness against advanced lung cancer
Perelman School of Medicine at the University of Pennsylvania

High response rates for patients with stage 4 lung cancer after anti-inflammatory drug added temporarily to immune checkpoint inhibitor therapy



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