McMaster University researchers are racing to create a home-based COVID-19 testing kit, which could potentially be ready to move forward for approvals and manufacturing within months.
Engineering and medical researchers at McMaster University have been racing to assist Woodbridge Foam Corporation in getting a new made-in-Canada mask designed, tested and certified, as supplies of existing medical masks become less certain.
The N95 respirator masks should be preserved for health-care workers involved in inserting breathing tubes for patients with COVID-19. More common medical masks are fine for all other COVID-19 treatment, says preliminary research from McMaster University.
An international team including McMaster University researchers has come together to issue guidelines for health-care workers treating intensive care unit (ICU) patients with COVID-19.
The author calls for the establishment of an independent international safeguarding agency for sports to handle athlete disclosures, investigate and process allegations, and to support victims of abuse. The expertise developed could then be used for preventive efforts. This agency would have to have sufficient cash and clout to be effective.
blood and tissue samples from 40 patients suffering from severe obesity taken during bariatric surgery were used. Half of the participants suffered from type 2 diabetes, while the other subjects showed insulin resistance without being diabetic. The researchers identified the bacterial genetic material in each of the tissues sampled, which came from the liver and three abdominal fat deposits. Based on the type of bacteria present and their relative abundance, the researchers were able to determine the bacterial signature for each tissue.
Technology can be used to track how the virus evolves over time, how it transmits between people, how well it survives outside the body, and to find answers to other questions.
The research team found that CBG had antibacterial activity against drug-resistant MRSA. It prevented the ability of that bacteria to form biofilms, which are communities of microorganisms that attach to each other and to surfaces; and it destroyed preformed biofilms and cells resistant to antibiotics. CBG achieved this by targeting the cell membrane of the bacteria. These findings in the laboratory were supported when mice with an MRSA infection were given CBG.
The study, recently published in the Journal of Adolescent Health, says identifying and treating mental health issues in young mothers is especially important as their health also affects the wellbeing of their children. The research recommends “further efforts should be directed at engaging and treating this high-risk group.”
A new group of antibiotics with a unique approach to attacking bacteria has been discovered, making it a promising clinical candidate in the fight against antimicrobial resistance. The newly-found corbomycin and the lesser-known complestatin have a never-before-seen way to kill bacteria, which is achieved by blocking the function of the bacterial cell wall. The discovery comes from a family of antibiotics called glycopeptides that are produced by soil bacteria.
The first type of influenza virus we are exposed to in early childhood dictates our ability to fight the flu for the rest of our lives, according to a new study from a team of infectious disease researchers at McMaster University and Université de Montréal.
The controversy about whether eggs are good or bad for your heart health may be solved, and about one a day is fine. A team of researchers from the Population Health Research Institute of McMaster University and Hamilton Health Sciences found the answer by analyzing data from three large, long-term multinational studies.
McMaster University researchers surveyed the data of patients of Hamilton’s two hospital systems over nine years and found 52 with low Vitamin C levels. This included 13 patients who could be diagnosed as having scurvy, and an additional 39 who tested positive for scurvy but did not have documented symptoms. Among those with scurvy, some were related to alcohol use disorder or to bariatric surgery but the majority were related to other causes of malnutrition such as persistent vomiting, purposeful dietary restrictions, mental illness, social isolation and dependence on others for food.
A team of physicists from McMaster University has developed a process to modify red blood cells so they can be used to distribute drugs throughout the body, which could specifically target infections or treat catastrophic diseases such as cancer or Alzheimer’s.
A team of chemists at McMaster University has discovered an innovative way to break down and dissolve the rubber used in automobile tires, a process which could lead to new recycling methods that have so far proven to be expensive, difficult and largely inefficient.
The VISION study looked at whether levels of a cardiac blood test, NT-proBNP, measured before surgery can predict cardiac and vascular complications. Higher levels of NT-proBNP, which can be caused by various anomalies in the cardiac muscle, such as stress, inflammation or overstretch, can help identify which patients are at greatest risk of cardiac complications after surgery. The study included 10,402 patients aged 45 years or older having non-cardiac surgery with overnight stay from 16 hospitals in nine countries.
The study involved 1,300 men and women who answered lifestyle questionnaires and had physical measures, blood samples and magnetic resonance imaging (MRI) completed.
A team of researchers at McMaster University has developed a self-cleaning surface that can repel all forms of bacteria, preventing the transfer of antibiotic-resistant superbugs and other dangerous bacteria in settings ranging from hospitals to kitchens.
New research from anthropologists at McMaster University and California State University, San Bernardino (CSUSB), is shedding light on ancient dietary practices, the evolution of agricultural societies and ultimately, how plants have become an important element of the modern diet.
Scientists were surprised when they found out that metformin caused the secretion of GDF15, a protein which is known to suppress appetite.
Approximately half of the patients were randomly assigned whole breast radiation, delivered once per day over three to five weeks. The other half received external beam APBI, considered to be the least invasive approach to partial breast irradiation, which was given twice a day over five to eight days. The study was long-term, with a median followup of 8.6 years.
A study led by Hamilton researchers has found a new way to interpret blood test results in patients who are investigated for blood clots in their lungs, a condition known as pulmonary embolism. This new approach applies to D-dimer blood tests, which are used by physicians to rule out the presence of a blood clot.
Researchers at McMaster University have created a new coating to prevent clotting and infection in synthetic vascular grafts, while also accelerating the body’s own process for integrating the grafted vessels.
Research from a leading international expert on the health of the Great Lakes suggests that the growing intensity and scale of pollution from plastics poses serious risks to human health and will continue to have profound consequences on the ecosystem.
After screening thousands of small molecules, the research team discovered a potent new antimicrobial they are calling MAC-545496 that is active against MRSA. Unlike conventional antibiotics, this new antimicrobial neither kills the staph infection nor halts its growth on its own, so the potential for antimicrobial resistance may be considerably lessened.
The McMaster study compared an MR model (Microsoft HoloLens) and a VR model (HTC VIVE) derived from a physical model to the actual model. The researchers focused on overall learning performance and the effects of stereopsis by using a strategy where the non-dominant eye was covered in one test condition.
Researchers from McMaster University have discovered striking variation in the underlying genetic machinery that orchestrates sexual differentiation in frogs, demonstrating that evolution of this crucial biological system has moved at a dramatic pace.
The research team looked at all research on the effects of cannabis use on illicit opioid use during methadone maintenance therapy, which is a common treatment for opioid use disorder, and found six studies involving more than 3,600 participants.
Six years ago the initial Three Wishes Project began at St. Joseph’s Healthcare Hamilton, when hospital staff asked patients or their families how they might honour the life and dignity of those dying in the intensive care unit. Staff would then help families by implementing these wishes. Now a study with three additional hospital intensive care unit sites in Toronto, Vancouver and Los Angeles, California has proven the project is a success elsewhere.
Researchers at McMaster University have found that a person’s first permanent molars carry a life-long record of health information dating back to the womb, storing vital information that can connect maternal health to a child’s health, even hundreds of years later.
The researchers determined that the rapid production of (p)ppApp by this enzyme toxin depletes cells of a molecule called ATP. ATP is often referred to as the ‘energy currency of the cell’ so when the supply of ATP is exhausted, essential cellular processes are compromised and the bacteria die
Researchers at McMaster University who examine the impact of exercise on the brain have found that high-intensity workouts improve memory in older adults.
With the increasing rate of multi-drug resistance, it is fundamental to identify new antibiotics. In this study, researchers found the synthesis of the vitamin biotin is integral for the growth of drug-resistant bacteria in human plasma. They were able to treat drug-resistant infections by inhibiting biotin synthesis in an infection mimicking human conditions. By inhibiting biotin synthesis, they have the potential to produce a novel class of antibiotics.
Researchers at McMaster University have identified several chemical signatures, detectable in blood and urine, that can accurately measure dietary intake, potentially offering a new tool for physicians, dieticians and researchers to assess eating habits, measure the value of fad diets and develop health policies.
The study, published today in PLOS ONE, found that more than 27 per cent of teens exceed recommended sugar intake and 21 per cent exceed recommended caffeine from soda and energy drinks. Males consumed more sodas and energy drinks than females, and youth in Grade 8 consumed more than those in Grade 10.
An international research team led by scientists from McMaster University has unearthed new evidence in Greece proving that the island of Naxos was inhabited by Neanderthals and earlier humans at least 200,000 years ago, tens of thousands of years earlier than previously believed.
The McMaster research team found muscle cells treated with statins released the amino acid called glutamate at much higher levels than muscle cells that were untreated. As glutamate is a potent activator of muscle pain receptors, this release was proposed to trigger the sensation of muscle pain.
A panel of international scientists led by researchers at Dalhousie and McMaster universities systematically reviewed the evidence and have recommended that most adults should continue to eat their current levels of red and processed meat.
The study shows that for those participants who do not have a history of heart disease or stroke that a simple cardiac risk score – a summary measure of factors such as blood pressure, diabetes, smoking, abdominal fat, and dietary factors – is associated with MRI-detected pre-clinical cerebrovascular disease like carotid artery plaque and silent strokes.
The trial was conducted on 1,495 patients 50 or older who had been able to walk before having a displaced femoral neck fracture, at 80 centres in the 10 countries of Canada, the U.S., Spain, United Kingdom, Netherlands, Norway, Finland, Australia, New Zealand and South Africa.
An international team of 30 scientists—led by researchers at McMaster University—is using one of the world’s largest telescopes to investigate and map extreme galaxy environments in brilliant detail.
An international team of scientists, led by researchers at McMaster University, has solved a centuries-old mystery of ‘Fraser’s Clawed Frog’, an unusual and elusive species found in West Africa.
For the World Federation of Hemophilia, Iorio assembled an international team of researchers from France, U.S. and U.K. to perform a meta-analysis of the registry data in countries with the most comprehensive registries of hemophilia, which were Australia, Canada, France, Italy, New Zealand and the U.K.
A large international study, involving more than 155,000 people in 21 countries, has found some of the risks are the same around the world, such as hypertension or low education, but other risks vary by a country’s level of economic development, such as air pollution and poor diet which impact health more in middle- and low-income countries.
Cardiovascular disease (CVD) is the major cause of death among middle-aged adults around the world; however, in high-income countries deaths from cancer have become twice as frequent as those from CVD.
People in sixteen communities received usual care and those in 14 communities had an intervention that included the initiation and monitoring of treatments and controlling risk factors by non-physician health workers using computer tablet-based management algorithms and counselling; the provision of free antihypertensive and statin medicines recommended by non-physician health workers under supervision of physicians, and the involvement of a friend or family member to support adherence to medications and lifestyle advice.
The new study, a collaboration of 130 hospitals in 31 countries, has shown that opening all the blockages is better than treating only the one blockage causing the heart attack. This led to a 26 per cent reduction in the patient’s risk of dying or having a recurrent heart attack.
The study analyzed data from studies across eight different psychiatric disorders, including major depressive disorder, bipolar disorder, borderline personality disorder, schizophrenia, eating disorders, and others.
Researchers at McMaster University who rush in after storms to study the behaviour of spiders have found that extreme weather events such as tropical cyclones may have an evolutionary impact on populations living in storm-prone regions, where aggressive spiders have the best odds of survival.
The study found that ‘silent’ covert strokes are actually more common than overt strokes in people aged 65 or older who have surgery
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