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Combined therapy makes headway for liver cancer

A drug that targets a protein known as phosphatidylserine boosted the response rate for hepatocellular carcinoma (HCC) patients receiving immunotherapy without compromising their safety, according to results of a phase two clinical trial conducted...
2-May-2024 4:05 PM EDT Add to Favorites

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Cancer cell–immune cell interactions predict immunotherapy response

By examining which genes were turned on and off in a mix of cell types from breast cancer biopsies, a team led by UT Southwestern Medical Center researchers developed a tool that can accurately predict which patients with breast cancer will respond...
29-Apr-2024 10:05 AM EDT Add to Favorites

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Blocking gene may halt growth of breast cancer cells

Shutting down a gene called PRMT5 stopped metastatic estrogen receptor-positive (ER+) breast cancer cells from growing after they acquired resistance to a standard therapy known as CDK4/6 inhibitors, UT Southwestern Medical Center researchers showed...
25-Apr-2024 10:05 AM EDT Add to Favorites

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Essential tremor triples dementia risk, UTSW study shows

Patients with a common movement disorder known as essential tremor (ET) developed dementia at three times the rate of similarly aged people in the general population, a study led by UT Southwestern Medical Center researchers shows. Their findings,...
24-Apr-2024 10:05 AM EDT Add to Favorites

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Drug targeting clear cell renal cell carcinoma shows promising approach

In a groundbreaking phase one clinical trial led by UT Southwestern Medical Center, a short interfering RNA (siRNA) drug directed to tumor cells effectively disrupted HIF2α, a key driver of clear cell renal cell carcinoma (ccRCC). Published in...
23-Apr-2024 11:05 AM EDT Add to Favorites

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Simulation reveals new mechanism for membrane fusion

An intricate simulation performed by UT Southwestern Medical Center researchers using one of the world’s most powerful supercomputers sheds new light on how proteins called SNAREs cause biological membranes to fuse.
22-Apr-2024 2:05 PM EDT Add to Favorites

Drug Combo Shows Promise in Restoring Cardiac Function

Heart failure patients may one day be able to restore cardiac function with medications that revive the body’s ability to regenerate heart muscle, a novel study at UT Southwestern Medical Center suggests.
16-Apr-2024 11:05 AM EDT Add to Favorites

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Oral Contraceptive Use May Reduce Muscle-Tendon Injuries

Women who take oral contraceptives may be significantly less likely to experience certain musculoskeletal injuries than women who do not take the drugs or men, according to a study by UT Southwestern Medical Center.
15-Apr-2024 2:05 PM EDT Add to Favorites


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UT Southwestern is an academic medical center, world-renowned for its research, widely respected for its teaching and training, and highly regarded for the quality of clinical care its faculty provides to patients at UT Southwestern University Hospitals & Clinics and its affiliated hospitals.

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