A study led by Università Cattolica at Rome and the Fondazione Policlinico Universitario Agostino Gemelli IRCCS in Rome, published in the prestigious journal PNAS, has revealed an important mechanism underlying Alzheimer and identified new therapeutic targets.
New research led by the University of Washington found that wildfire smoke is especially hazardous to people's memory health. An analysis of the health care records of 1.2 million Southern California residents found that higher long-term smoke exposure was associated with a significant increase in the odds that a person would be diagnosed with dementia.
University Hospitals Brain Health & Memory Center is now treating patients with KISUNLA™ (donanemab), a Food and Drug Administration-approved medication for the treatment of Alzheimer’s disease. UH is the only health system in Northeast Ohio currently offering these infusion treatments.
People with Alzheimer’s exhibit a loss of motor control along with cognitive decline, and one of the earliest signs of this decay can be spotted in involuntary eye movements known as saccades. These quick twitches of the eyes in Alzheimer’s patients are often slower, less accurate, or delayed compared to those in healthy individuals.
A doctoral student in speech-language pathology at Université de Montréal is testing the use of audiovisual content to support communication in people with dementia.
A new study from the University of Delaware will look at Alzheimer's disease (AD) and examine how changes in arterial stiffness and brain tissue in midlife adults could contribute to cognitive decline. The study aims to pinpoint early risk factors and explore preventive interventions.
Researchers at Washington University School of Medicine in St. Louis have linked disease-related proteins and genes to identify specific cellular pathways responsible for Alzheimer’s genesis and progression. The proteins were gathered from cerebrospinal fluid and are a good proxy for activity in the brain. Several of them may be potential targets for therapies.
Irvine, Calif., Nov. 14, 2024 — Researchers led by the University of California, Irvine are the first to reveal how two neural circuits located in the brain’s retrosplenial cortex are directly linked to spatial navigation and memory storage. This discovery could lead to more precise medical treatments for Alzheimer’s disease and other cognitive disorders by allowing them to target pathway-specific neural circuits.
In a groundbreaking study, researchers at McMaster University have identified a potential treatment for Sandhoff and Tay-Sachs diseases—two rare, often fatal lysosomal storage disorders that cause progressive damage to nerve cells in the brain and spinal cord.
After years of investigating the diseases’ underlying mechanisms, the research team has identified an existing FDA-approved drug that could significantly improve quality of life for affected patients and their families.
The University of Kentucky Sanders-Brown Center on Aging Director Linda Van Eldik, Ph.D., hopes to shed light on how specific brain cells may contribute to the progression of Alzheimer’s disease, paving the way for potential new therapeutic approaches.Van Eldik recently received a three-year, $300,000 award from the BrightFocus Foundation to support her research project, “Relationship between astrocyte p38 MAPK, neuroinflammation, and Alzheimer pathology.
Experts on healthy aging from Cedars-Sinai’s growing Center for Translational Geroscience and Geriatrics Program will present their latest research and clinical advances at The Gerontological Society of America’s (GSA) 2024 Annual Scientific Meeting in Seattle, Nov. 13-16.
The Acoustical Society of America will host two virtual press conferences Monday, Nov. 18. ASA’s 187th meeting will be held online, and reporters are invited to join technical sessions Nov. 19-21. Media are invited to join the virtual press conferences for presentations on dinosaur acoustics, using camp stove waste for new outdoor power sources, predicting Alzheimer’s with in-ear microphones, and more.
Older people who are sleepy during the day or lack enthusiasm for activities due to sleep issues may be more likely to develop a syndrome that can lead to dementia, according to a study published in the November 6, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.
A review article entitled “Prevalence of Antibiotic Resistance in Older Adults and Alzheimer’s Disease Patients: A Systematic Review and Meta-Analysis,” is now published in the Journal Alzheimer’s Disease Reports.