Feature Channels: Genetics

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Released: 7-Aug-2024 9:00 AM EDT
Tip Sheet: BRCA cancer risks for men, a new way to classify brain tumors, funding for bile duct cancer — and cancer care in LGBTQ+ communities
Fred Hutchinson Cancer Center

Below are summaries of recent Fred Hutch Cancer Center research findings, patient stories and other news.

Newswise: Polar Bears in Canada’s High Arctic Are the Most  Vulnerable to Climate Change, According to New Genetic Analysis
6-Aug-2024 2:00 PM EDT
Polar Bears in Canada’s High Arctic Are the Most Vulnerable to Climate Change, According to New Genetic Analysis
University of Manitoba

Researchers from leading institutions including Polar Bears International, Environment and Climate Change Canada, the San Diego Zoo Wildlife Alliance, the University of Manitoba, and MacEwan University have analyzed all of Canada’s polar bear populations and found that the most northern polar bears, those in Canada’s High Arctic, are less likely to be able to adapt to a rapidly warming Arctic.

30-Jul-2024 3:05 PM EDT
Your Best Friend From High School? Here’s Why Their Genes Mattered
Rutgers University-New Brunswick

Peer social genetic effects – the influence of a social partner’s genotype on the observable traits of another – influence risk for addiction and psychiatric disorders later in life, a Rutgers researcher finds

Newswise: The Battle against glioblastoma: classifying molecular profiles for precision medicine
Released: 6-Aug-2024 11:05 PM EDT
The Battle against glioblastoma: classifying molecular profiles for precision medicine
Chinese Academy of Sciences

A transformative study has provided a profound understanding of glioblastoma's molecular subtypes, revealing the nuances of cellular heterogeneity and the mechanisms behind resistance to treatment. This critical research not only enhances our comprehension of this aggressive cancer but also opens new frontiers for the precision-targeting of therapies, potentially improving patient outcomes significantly.

Released: 6-Aug-2024 2:05 PM EDT
UC Irvine-led team reveals how TREM2 genetic mutation affects late-onset Alzheimer’s
University of California, Irvine

Researchers led by the University of California, Irvine have discovered how the TREM2 R47H genetic mutation causes certain brain areas to develop abnormal protein clumps, called beta-amyloid plaques, associated with late-onset Alzheimer’s disease.

Newswise: Danforth Center Announces New Assistant Member
Released: 6-Aug-2024 9:05 AM EDT
Danforth Center Announces New Assistant Member
Donald Danforth Plant Science Center

The Donald Danforth Plant Science Center announced today that Nadia Shakoor, PhD, has joined as Assistant Member. She is an expert in sorghum genetics, a versatile and drought-resistant cereal grain vital for food, feed and fuel in many arid and semi-arid regions of the world.

Newswise:Video Embedded video-available-fda-changes-to-laboratory-developed-test-regulation-livestreamed-expert-panel
VIDEO
Released: 5-Aug-2024 11:05 AM EDT
Video and Transcript Available - FDA Changes to Laboratory Developed Test Regulation: Livestreamed Expert Panel
Newswise

Live from the annual conference of the Association for Diagnostics & Laboratory Medicine (ADLM, formerly AACC), experts will discuss how the new FDA rule on laboratory developed tests will hinder patient care. This rule will place these tests under duplicative FDA oversight, even though laboratory developed tests are already regulated by the Centers for Medicare & Medicaid Services. This will force many labs to stop performing these essential tests, which play a critical role in diagnosing rare disorders, such as inherited genetic conditions in newborns.

       
Newswise: Early Menopause Linked to Increased Breast Cancer Risk
Released: 5-Aug-2024 11:00 AM EDT
Early Menopause Linked to Increased Breast Cancer Risk
Huntsman Cancer Institute at the University of Utah

Early menopause significantly raises breast cancer risk, highlighting the need for proactive health screenings, according to research from Huntsman Cancer Institute and the Spencer Fox Eccles School of Medicine.

Newswise: Cancer Research Institute Announces New Lloyd J. Old STARs Class
Released: 5-Aug-2024 11:00 AM EDT
Cancer Research Institute Announces New Lloyd J. Old STARs Class
Cancer Research Institute

CRI has announced its new class of 2024 Scientists Taking Risks (STARs) grant recipients who are expert cancer immunotherapy researchers.

Newswise: New Executive Director Announced for the American Thyroid Association
Released: 5-Aug-2024 9:05 AM EDT
New Executive Director Announced for the American Thyroid Association
American Thyroid Association

The American Thyroid Association (ATA) announces new Executive Director, Pam Mechler

Newswise: What Researchers Know about the Genetic Complexity of Schizophrenia, To Date
Released: 2-Aug-2024 2:05 PM EDT
What Researchers Know about the Genetic Complexity of Schizophrenia, To Date
University of North Carolina School of Medicine

A new review article written by researchers at the UNC School of Medicine and the Karolinska Institutet, outline the genetic, neurobiological, and environmental foundations that contribute to the development of schizophrenia.

30-Jul-2024 10:05 AM EDT
Researchers develop promising therapy treatment that can kill glioblastoma cells in newly discovered brain pathway
McMaster University

A new pathway that is used by cancer cells to infiltrate the brain has been discovered by a team of Canadian and American research groups led by the Singh Lab at McMaster University. The research also reveals a new therapy that shows promise in blocking and killing these tumors.

Newswise:Video Embedded when-it-comes-to-dna-replication-humans-and-baker-s-yeast-are-more-alike-than-different
VIDEO
30-Jul-2024 11:05 AM EDT
When it comes to DNA replication, humans and baker’s yeast are more alike than different
Van Andel Institute

Humans and baker’s yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies published in the journals Science and Proceedings of the National Academy of Sciences.

   
Released: 1-Aug-2024 11:05 AM EDT
Hitachi High-Tech Acquires Majority Interest in Nabsys
Nabsys

Hitachi High-Tech Corporation (Hitachi High-Tech) and Nabsys 2.0 LLC (Nabsys) announced today that Hitachi High-Tech has acquired a majority interest in Nabsys, a developer and manufacturer of instrumentation and consumables for the analysis of genomic structural variation.

Newswise: Targeting protein has potential to treat leukemia, lymphoma
Released: 1-Aug-2024 10:05 AM EDT
Targeting protein has potential to treat leukemia, lymphoma
UT Southwestern Medical Center

Targeting a protein called ZFP574 suppressed leukemia in a mouse model of the disease, UT Southwestern Medical Center researchers showed in a new study. Their findings, published in PNAS (Proceedings of the National Academy of Sciences), could lead to new treatments for leukemias and lymphomas in cancer patients.

30-Jul-2024 3:05 PM EDT
Which Strains of Tuberculosis Are the Most Infectious?
Harvard Medical School

Highly localized TB strains are less infectious in cosmopolitan cities and more likely to infect people from the geographic area that is the strain’s natural habitat.

   
Newswise: MD Anderson and collaborators to launch project studying T cells on International Space Station
Released: 31-Jul-2024 9:00 AM EDT
MD Anderson and collaborators to launch project studying T cells on International Space Station
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center and collaborators are initiating a research project that will send T cells to the International Space Station (ISS) to study the effects of prolonged microgravity on cell differentiation, activation, memory and exhaustion.

   
Released: 30-Jul-2024 10:30 AM EDT
Expert on Alzheimer’s Therapeutic Development AAIC 2024
University of Miami Health System, Miller School of Medicine

Our grant proprosal is to identify how two protective mechanisms work and then test them in both European and Amerindian APOE4 genes to see if they work in those genetic backgrounds as well as African.

Released: 30-Jul-2024 10:05 AM EDT
New findings on possible therapies to target oncogenic transcription factors in multiple cancer types
Michigan Medicine - University of Michigan

A new study from the University of Michigan Health Rogel Cancer Center furthers research that suggests the potential of developing new cancer treatments to target oncogenic transcription factors by indirectly affecting their ability to access enhancer DNA in chromatin. The findings appear in Cancer Cell.



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