Many living organisms are able to regenerate damaged or lost tissue, but why some are particularly good at this and others are not is not fully understood. Molecular biologists Alexander Stockinger, Leonie Adelmann and Florian Raible from the Max Perutz Labs at the University of Vienna have now made an important contribution to clarifying this question in a new study.
Scientists at St. Jude Children’s Research Hospital identified a link between glutamine metabolism and red blood cell maturation, showing how disruption of the process can drive disease.
UCLA researchers have uncovered a surprising new role for netrin1, a crucial protein in neural development, as a regulator that limits bone morphogenetic protein signaling in the developing spinal cord.
Cedars-Sinai investigators are one step closer to manufacturing stem cells in space, which could speed up the development of new medical therapies on Earth. The first published data from the experiments conducted on a private space mission appeared in the peer-reviewed Nature portfolio journal NPJ Microgravity.
The Maryland Stem Cell Research Commission (MSCRC) announces the release of a Request for Applications (RFA) for the Maryland Stem Cell Research Fund's (MSCRF) second funding cycle of Fiscal Year 2025 (FY25).
Heart muscle cells grown from stem cells show promise in monkeys with a heart problem that typically results from a heart defect sometimes present at birth in humans, according to new research from the University of Wisconsin–Madison and Mayo Clinic.
UCLA investigators have shown that that combining pembrolizumab, an immunotherapy drug, with standard chemotherapy can improve treatment outcomes for patients with small cell bladder cancer and small cell/neuroendocrine prostate cancer.
Researchers at UC San Diego identify a key pathway leading to neurodegeneration in early stages of ALS, hinting at the potential for short-circuiting the progression of the fatal disease if diagnosed early.
Some animal species seem to possess extraordinary regenerative abilities. How do they do it? And could we learn from them to defy the grim reaper ourselves?
As células-tronco cultivadas em microgravidade a bordo da Estação Espacial Internacional (EEI) possuem qualidades únicas que poderão, um dia, ajudar a potencializar as novas bioterapias e a curar doenças complexas, de acordo com dois pesquisadores da Mayo Clinic. A análise da pesquisa pelo pesquisador Fay Abdul Ghani e pelo Dr. e Ph.D. Abba Zubair, publicada na NPJ Microgravity, descobriu que a microgravidade pode fortalecer o potencial regenerativo das células. O Dr. Zubair é especialista em medicina laboratorial e diretor médico do Centro de Bioterapias Regenerativas na Mayo Clinic, na Flórida. Abdul Ghani é um tecnólogo em pesquisa da Mayo Clinic. A microgravidade é a ausência de peso ou gravidade próxima a zero.
Las células madre cultivadas en microgravedad a bordo de la Estación Espacial Internacional (EEI) poseen cualidades únicas que algún día podrán ayudar a potenciar las nuevas bioterapias y curar enfermedades complejas, según dos investigadores de Mayo Clinic. El análisis de la investigación por el investigador Fay Abdul Ghani y por el Dr. y Ph.D. Abba Zubair, publicado en NPJ Microgravity ha hallado que la microgravidad puede fortalecer el potencial regenerativo de las células. El Dr. Zubair es especialista en medicina de laboratorio y director médico del Centro de Bioterapias Regenerativas en Mayo Clinic, Florida. Abdul Ghani es tecnólogo de investigación en Mayo Clinic. La microgravedad es la ausencia o gravedad cercana a cero.
جاكسونفيل، فلوريدا — يقول باحثان من مايو كلينك إن الخلايا الجذعية التي تنمو في ظروف انعدام الجاذبية على متن محطة الفضاء الدولية (ISS) تتميز بخصائص فريدة قد تساهم في تسريع تطوير علاجات بيولوجية جديدة وعلاج الأمراض المعقدة في المستقبل. التحليل البحثي الذي أجرته فاي عبد الغني والدكتور عبا زبير، الحاصل على درجة الدكتوراه في الطب، والذي نُشر في مجلة NPJ Microgravity، يكشف أن انعدام الجاذبية يمكن أن يعزز من القدرة التجديدية للخلايا. يعد الدكتور زبير خبيرًا في الطب المخبري والمدير الطبي لمركز العلاج الحيوي التجديدي في مايو كلينك بفلوريدا. أما عبد الغني فهي تقنيّة بحثية في مايو كلينك. يعرف انعدام الجاذبية بكونه حالة من انعدام الوزن أو الجاذبية القريبة من الصفر.
October is Breast Cancer Awareness Month, and fittingly, University of New Mexico Comprehensive Cancer Center biologist Curt Hines, PhD, has published a pair of papers that comprehensively describe the twelve major types of cells in the human breast.
The intrinsic heterogeneity of metabolic dysfunction-associated fatty liver disease (MASLD) and the intricate pathogenesis have impeded the advancement and clinical implementation of therapeutic interventions, underscoring the critical dema
The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.
The intrinsic heterogeneity of metabolic dysfunction-associated fatty liver disease (MASLD) and the intricate pathogenesis have impeded the advancement and clinical implementation of therapeutic interventions, underscoring the critical dema
Researchers publishing in ACS’ Journal of Agricultural and Food Chemistry have created a prototype cultured pork using a new material: kafirin proteins isolated from red sorghum grain.
A new international trial is investigating the efficacy and safety of gene therapy in patients with Hurler syndrome and will compare results of gene therapy against BMT which is the current standard of care. UCSF Benioff Children’s Hospitals are among three sites in the U.S. and seven in the world now enrolling patients for the clinical trial.
The National University of Singapore (NUS) will be taking a significant leap forward in synthetic biology, leveraging its deep expertise and cutting-edge innovations to usher a new paradigm for green manufacturing, driven by this rapidly evolving field. Over the next six years, the University plans to dedicate substantial resources and efforts – estimated to value around S$120 million (US$90.6 million) - to firmly establish synthetic biology as a foundational pillar of NUS’ innovation ecosystem, driving transformative benefits for Singapore across multiple sectors.
BACKGROUNDMyocardial ischemia-reperfusion injury (MIRI) poses a prevalent challenge in current reperfusion therapies, with an absence of efficacious interventions to address the underlying causes. AIMTo investigate whether the extracellula
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