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Article ID: 700944

A Trojan Horse Delivery of Possible Treatment for a Rare, Potentially Deadly, Blood-Clotting Disorder

University of Alabama at Birmingham

In proof-of-concept experiments, researchers have highlighted a potential therapy for a rare but potentially deadly blood-clotting disorder, TTP. Researchers deliver a therapeutic enzyme via the cellular equivalent of a Trojan Horse, using platelets to protect the key enzyme hidden inside.

Released:
21-Sep-2018 3:30 PM EDT
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Article ID: 700530

Immune Response Mechanism Described for Fate Determination of T Cells

University of Alabama at Birmingham

In a paper published in the journal Science, researchers have detailed a mechanism that sets the stage for the fate decision that gives rise to two major subsets of effector cells: T follicular helper cells and non-T follicular helper cells, known as Tfh and non-Tfh cells.

Released:
13-Sep-2018 3:05 PM EDT
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Article ID: 700064

A Joint Effort to Understand Cartilage Development

Keck Medicine of USC

Anyone with arthritis can appreciate how useful it would be if scientists could grow cartilage in the lab. To this end, Keck School of Medicine of USC scientists in the USC Stem Cell laboratory of Denis Evseenko, MD, PhD, collaborated with colleagues at several institutions to provide new insights into how gene activity drives the development of cartilage. Their findings appear today in Nature Communications.

Released:
7-Sep-2018 5:00 AM EDT
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  • Embargo expired:
    5-Sep-2018 9:00 AM EDT

Article ID: 699905

Hypertension Drugs Could Prevent Memory Loss in Lupus Patients, Study Suggests

The Rockefeller University Press

Researchers from The Feinstein Institute for Medical Research have discovered that the activation of brain cells called microglia likely contributes to the memory loss and other cognitive impairments suffered by many patients with systemic lupus erythematosus (SLE). The study, which will be published September 5 in the Journal of Experimental Medicine, shows that ACE inhibitors—a class of drugs commonly used to treat hypertension—can block this process in mice and might therefore be used to preserve the memory of lupus patients.

Released:
4-Sep-2018 8:05 AM EDT

Article ID: 699964

American College of Rheumatology Releases First-Ever Rheumatic Disease Report Card

American College of Rheumatology (ACR)

The American College of Rheumatology (ACR) today released the Rheumatic Disease Report Card: Raising the Grade on Rheumatology Care in America, a first-of-its-kind report that evaluates just how difficult it can be to live well with a rheumatic disease in the United States.

Released:
4-Sep-2018 3:05 PM EDT

Article ID: 699884

Research Presents Evidence of Faster Progression of Disablement in Stiff Person Syndrome

American Association of Neuromuscular and Electrodiagnostic Medicine (AANEM)

The American Association of Neuromuscular & Electrodiagnostic Medicine (AANEM) is honoring Goran Rakocevic, MD, with the 2018 Best Abstract Award for his abstract, Quantitative Clinical and Autoimmune Assessments in Stiff Person Syndrome: Evidence for a Progressive Disorder.

Released:
31-Aug-2018 3:05 PM EDT
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Article ID: 699789

Stigmatizing Views and Myths about Psoriasis Are Pervasive in the United States

Perelman School of Medicine at the University of Pennsylvania

The stigma associated with the autoimmune disease psoriasis may lead people to avoid patients who show signs of the condition, including not wanting to date, shake hands, or have people in their homes if they suffer from the disease. New multidisciplinary research involving both psychologists and dermatologists from the Perelman School of Medicine at the University of Pennsylvania is the first to examine how common this stigma may be among the general population of the United States as well as among medical students.

Released:
30-Aug-2018 8:05 AM EDT

Article ID: 699587

Muscle Disease Patients Gather to Learn About Myositis

Myositis Association

TMA hosts its Annual Patient Conference at the Louisville Marriott Downtown on September 6-9. With more than 500 myositis patients and family members in attendance, this conference promises to be the largest in TMA history.

Released:
28-Aug-2018 1:05 PM EDT
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Article ID: 699285

Tulane Rheumatologist Named Doctor of the Year by Scleroderma Foundation

Tulane University

Dr. Lesley Ann Saketkoo, an associate professor of clinical medicine at Tulane University School of Medicine, has been named Doctor of the Year by the Scleroderma Foundation.

Released:
21-Aug-2018 12:05 PM EDT

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