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Science

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Antibiotics, Microbiology, Science, Bacteria, Molecular, molecular pencil sharpener , E. Coli Bacteria, TldD, prodrugs, Toxins, Cells, Cell Biology, Rutgers, Rutgers University-New Brunswick, New Jersey, NJ

Antibiotics From a ‘Molecular Pencil Sharpener’

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Rutgers University–New Brunswick and other institutions have discovered a “molecular pencil sharpener” that chews away its outer coating to release a powerful antibiotic. Their discovery opens the door to finding new antibacterial agents and drugs to fight toxins.

Medicine

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A Little Myelin Goes a Long Way to Restore Nervous System Function

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A team of researchers from the University of Wisconsin-Madison reports that in long-lived animals, renewed but thin myelin sheaths are enough to restore the impaired nervous system and can do so for years after the onset of disease.

Medicine

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Asthma, Microbiome, Pulmonary Function, Inhaled Corticosteroids

New Asthma Biomarkers Identified From Lung Bacteria

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New research from the University of Illinois at Chicago College of Medicine suggests that the lung microbiome plays a significant role in asthma severity and response to treatment.

Medicine

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Researchers Identify Protein That Plays Key Role in Diabetic Blindness

Researchers at University of Utah Health have identified a protein (ARF6) that when inhibited reduces diabetic retinopathy, a condition that results when blood vessels at the back of the eye leak fluid into the eye, impairing vision.

Medicine

Science

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Fred Kavli Keynote Lecture: What a Tiny Worm Taught Cori Bargmann about the Brain

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The scientific leader of Chan Zuckerberg Initiative to kick off 2017 ASCB|EMBO Meeting in Philadelphia.

Medicine

Science

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Cryo Electron Microscope, cryo-EM, cryo-electron microscopy, Structural Biology

Cryo-EM Reveals Ignition Mechanism for DNA Replication

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An international team of scientists, led by structural biologists at Van Andel Research Institute, has shed new light on a critical step in DNA replication, offering fresh insights into a fundamental process of life and driver of many different diseases, including cancer.

Medicine

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Cancer, Cells, Biology, Cell Biology

New Study Shows How Cells Can Be Led Down Non-Cancer Path

As cells with a propensity for cancer break down food for energy, they reach a fork in the road: They can either continue energy production as healthy cells, or shift to the energy production profile of cancer cells. In a new study, University of Wisconsin–Madison researchers map out the molecular events that direct cells’ energy metabolism down the cancerous path. Their findings could lead to ways to interrupt the process.

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B cell leukemia

Penn Study Links Mutations in Notch Gene to Role in B Cell Cancers

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Researchers found that in B cell tumors, mutated overactive versions of the Notch protein directly drive the expression of the Myc gene and many other genes that participate in B cell signaling pathways. Myc is a critical gene in governing cell proliferation and survival.

Medicine

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disorder of sex development, Intersex

How Hospitals Respond When It’s Uncertain if the Newborn Is a Boy or a Girl

When babies are born with atypical sex anatomy, how a hospital responds has a major impact on a family’s experience and decisions about sometimes irreversible procedures.

Medicine

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Hydrogel, Organoids, human intestinal organoids, Crohn's Disease, Matrix, Extracellular Matrix

Synthetic Hydrogels Deliver Cells to Repair Intestinal Injuries

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By combining engineered polymeric materials known as hydrogels with complex intestinal tissue known as organoids – made from human pluripotent stem cells – researchers have taken an important step toward creating a new technology for controlling the growth of these organoids and using them for treating wounds in the gut that can be caused by disorders such as inflammatory bowel disease (IBD).







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