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Article ID: 693409

‘Incompatible’ Donor Stem Cells Cure Adult Sickle Cell Patients

University of Illinois at Chicago

Doctors at the University of Illinois Hospital have cured seven adult patients of sickle cell disease, an inherited blood disorder primarily affecting the black community, using stem cells from donors previously thought to be incompatible, thanks to a new transplant treatment protocol.

Released:
24-Apr-2018 4:40 PM EDT
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Article ID: 693386

Genetic Transcription ‘Pause’ Is Focus of NASA Grant

Cornell University

Almost all forms of animal life – from fruit flies to butterflies to mammals – contain a pause in transcription, a step that appears to allow the transcription machinery to take a break to fine-tune its copying process. No one knows when this pause originated in the evolution of life. Charles Danko, assistant professor of genetics and molecular biology at the Cornell University Baker Institute for Animal Health, will investigate with a three-year, $790,000 grant from NASA’s Exobiology program.

Released:
24-Apr-2018 2:05 PM EDT
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Article ID: 693351

In Huntington's Disease, Heart Problems Reflect Broader Effects of Abnormal Protein

Children's Hospital of Philadelphia

Researchers investigating a key signaling protein in Huntington’s disease describe deleterious effects on heart function, going beyond the disease’s devastating neurological impact. By adjusting protein levels affecting an important biological pathway, the researchers improved heart function in mice, shedding light on the biology of this fatal disease.

Released:
24-Apr-2018 2:00 PM EDT
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Article ID: 693377

What Can a Tasty Milkshake Teach Us About the Genetics of Heart Disease?

American Society for Biochemistry and Molecular Biology (ASBMB)

A genomic analysis of a large study population has identified uncommon gene variants involved in responses to dietary fats and medicine. Although these variants are rare, they may play a large role in a carrier's risk of heart disease.

Released:
24-Apr-2018 1:05 PM EDT
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Article ID: 693360

UAH Student Part of Discovery That May Improve Treatment of Type 1 Diabetes

University of Alabama Huntsville

UAH Ph.D. student Shristi Shrestha is honing her skills in single-cell gene expression as a graduate research assistant at the HudsonAlpha Institute for Biotechnology. She recently served as first co-author of a paper that was published in the journal "Cell Reports."

Released:
24-Apr-2018 12:05 PM EDT
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  • Embargo expired:
    24-Apr-2018 12:00 PM EDT

Article ID: 692933

Mental, Not Physical, Fatigue Affects Seniors’ Walking Ability

American Physiological Society (APS)

Low “mental energy” may affect walking patterns in older adults more than physical fatigue. New research about the relationship between walking ability and self-reported mood will be presented today at the American Physiological Society (APS) annual meeting at Experimental Biology 2018 in San Diego.

Released:
16-Apr-2018 6:00 PM EDT
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  • Embargo expired:
    24-Apr-2018 12:00 PM EDT

Article ID: 693148

How Colorectal Cancer Cells Spread to the Liver

Sanford Burnham Prebys Medical Discovery Institute

A new study by Sanford Burnham Prebys Medical Discovery Institute (SBP) researchers helps explain the connection between a tumor suppressor called protein kinase C zeta (PKC zeta) and metastatic colorectal cancer.

Released:
20-Apr-2018 12:00 PM EDT
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  • Embargo expired:
    23-Apr-2018 3:15 PM EDT

Article ID: 692766

Hemp Shows Potential for Treating Ovarian Cancer

Federation of American Societies for Experimental Biology (FASEB)

Sara Biela and Chase Turner, graduate students in the lab of Wasana Sumanasekera at Sullivan University College of Pharmacy in Kentucky, will present new findings tied to hemp’s anti-cancer properties at the American Society for Biochemistry and Molecular Biology annual meeting during the 2018 Experimental Biology meeting to be held April 21-25 in San Diego.

Released:
16-Apr-2018 9:00 AM EDT
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Article ID: 693281

Watch Your Step: How Vision Leads Locomotion

University of Texas at Austin (UT Austin)

Using new technologies to track how vision guides foot placement, researchers at The University of Texas at Austin come one step closer in determining what is going on in the brain while we walk, paving the way for better treatment for mobility impairments — strokes, aging and Parkinson’s — and technology development — prosthetics and robots.

Released:
23-Apr-2018 12:05 PM EDT
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Social and Behavioral Sciences

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Article ID: 693278

New Cell Therapy Aids Heart Recovery—Without Implanting Cells

Columbia University School of Engineering and Applied Science

A team led by Columbia University Biomedical Engineering Professor Gordana Vunjak-Novakovic has designed a creative new approach to help injured hearts regenerate by applying extracellular vesicles secreted by cardiomyocytes rather than implanting the cells. The study shows that the cardiomyocytes derived from human pluripotent stem cells (derived in turn from a small sample of blood) could be a powerful, untapped source of therapeutic microvesicles that could lead to safe and effective treatments of damaged hearts.

Released:
23-Apr-2018 11:05 AM EDT
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