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Transplantation

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Medicine

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Disparities, Stem Cell Therapy, Multiple Myeloma

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 11-Dec-2017 6:00 PM EST

Science

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multiple myelmoma, Cancer, Hematologic Cancers

Study Explores Use of Checkpoint Inhibitors After Relapse From Donor Stem Cell Transplant for Hematologic Cancers

Immunotherapy agents known as checkpoint inhibitors have shown considerable promise in patients with hematologic cancers who relapse after a transplant with donor stem cells. Preliminary results from the first clinical trial in these patients of one such agent – nivolumab – indicate that along with signs of effectiveness, it also produced significant side effects at the dose initially studied. The findings indicate a need for further clinical trials in this group before being considered for off-label use with these patients, Dana-Farber Cancer Institute investigators report.

Medicine

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Cancer, Hematology, stem cell tranplantation, Graft Versus Host Disease, Immunotherapy

Immunotherapy Drug for Rheumatoid Arthritis Nearly Eliminates Severe Acute Graft-Versus-Host Disease after Hematopoietic Stem Cell Transplant

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Results from a phase 2 clinical trial, presented by Seattle Children’s Research Institute at the 59th American Society of Hematology (ASH) Annual Meeting, show that the drug Abatacept (Orencia) nearly eliminated life-threatening severe acute graft-versus-host disease (GvHD) in patients receiving hematopoietic stem cell transplants.

Medicine

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Kidney Transplant, Kidney, Kidney Advocacy, Liver Transplant, Kidney Transplantation, Kidney Transplants, Nephrotic Syndrome, Diabetes, High Blood Pressure, deceased donor, deceased donor liver transplant, Living Donor Kidney Transplant, Living Donor

Two Alabamians Push UAB Hospital Past Milestone of 10,000 Kidney Transplants

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The hope given from a deceased donor, and a sibling, give two kidney transplant recipients a chance to live

Medicine

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Bortezomib, Kidney Transplant

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 14-Dec-2017 5:00 PM EST

Medicine

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kidney discard, Transplantation

Many Donor Kidneys that Are Discarded May Be Suitable for Transplantation

• In an analysis of pairs of kidneys from the same donor in which 1 kidney was used but the other was discarded, the kidneys that were used tended to perform well. • The majority of discarded kidneys could have potentially been transplanted with good outcomes.

Medicine

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Children's Hospital Los Angeles, Leukemia, Stem Cell Transplant, Donor, Acute Myeloid Leukemia, be the match, National Marrow Donor Program, Chemotherapy, Stem Cells, Cancer

#FiercePierce: 2-Year-Old Patient Beats Back Leukemia and Inspires Thousands of Potential Stem Cell Donors

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2-year-old Children's Hospital Los Angeles patient Pierce Kelly beats leukemia thanks to a stem cell donor in France and inspires thousands of potential donors.

Medicine

Science

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Researchers 3D Print Lifelike Artificial Organ Models

A team of researchers led by the University of Minnesota has 3D printed lifelike artificial organ models that mimic the exact anatomical structure, mechanical properties, and look and feel of real organs. These patient-specific organ models, which include integrated soft sensors, can be used for practice surgeries to improve surgical outcomes in thousands of patients worldwide.

Medicine

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Hand Transplant, bilateral hand transplant, MCR, massive cortical reorganization, Pediatrics, Radiology, Neurology

Brain Remaps Itself in a Child with Double Hand Transplant

The first child to undergo a successful hand transplant also is the first child in whom scientists have detected massive changes in how sensations from the hands are represented in the brain. The brain reorganization is thought to have begun six years before the transplant, when the child had both hands amputated because of a severe infection during infancy. Notably, after he received transplanted hands, the patient’s brain reverted toward a more typical pattern.

Medicine

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First Total Removal of Pancreas and Successful Islet Autotransplant in Brooklyn for Treatment of Chronic Pancreatitis

For the first time in Brooklyn, a procedure has been performed implanting a patient’s own insulin-producing pancreatic cells ("islets") after the total removal of pancreas.







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