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Service members who have had a moderate, severe, or penetrating traumatic brain injury, or TBI, are at a greater risk for subsequently developing brain cancer, according to a collaborative study led by researchers at the Uniformed Services University (USU) published February 15, 2024, in JAMA Open Network. On the other hand, those who have suffered mild TBI, or concussion – which is much more common – may not be associated with later brain cancer diagnoses, the study finds.

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Beau Turfle is all smiles, says his family. But even at 3 months old, he’s already overcome a life-threatening heart concern.

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Con la edad, las células pueden experimentar senescencia, un estado en el que dejan de crecer, pero continúan liberando moléculas inflamatorias que degradan los tejidos. Cuando una persona es joven, el sistema inmunitario responde y elimina las células senescentes, a menudo llamadas células zombis. Sin embargo, las células zombis persisten y contribuyen a varios problemas de salud y enfermedades que se asocian con la edad. En dos estudios, los investigadores de Mayo Clinic explicaron la biología de las células que envejecen.

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Columbia Biomedical Engineer Ke Cheng has developed a technique that uses inhalation of exosomes, or nanobubbles, to directly deliver IL-12 mRNA to the lungs of mice.

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Drug-loaded 3D printed films could change cancer treatments forever as world first research from the University of South Australia shows that new films not only kill more than 80% of liver cancer cells but could also significantly reduce recurrence rates while minimizing systematic toxicities of traditional chemotherapy.

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Scientists at Cold Spring Harbor Laboratory (CSHL) and the University of California, Davis have reached a new breakthrough in pancreatic cancer research—eight years in the making.

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The American College of Sports Medicine and its Exercise is Medicine Program (EIM) announced today that former NFL linebacker Chris Draft has joined the Moving Through Cancer Task Force Board.

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A novel three-drug combination achieved notable responses in patients with advanced HER2-negative breast cancer, according to new research directed by investigators from the Johns Hopkins Kimmel Cancer Center.

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Researchers from the Icahn School of Medicine at Mount Sinai, in collaboration with the Clinical Proteomic Tumor Analysis Consortium of the National Institutes of Health, The University of Texas MD Anderson Cancer Center, Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, and others, have unveiled a detailed understanding of immune responses in cancer, marking a significant development in the field. The findings were published in the February 14 online issue of Cell. Utilizing data from more than 1,000 tumors across 10 different cancers, the study is the first to integrate DNA, RNA, and proteomics (the study of proteins), revealing the complex interplay of immune cells in tumors. The data came from the Clinical Proteomic Tumor Analysis Consortium (CPTAC), a program under the National Cancer Institute.

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New research from the University of Ottawa proposes using vanoxerine as a safe method for potentially eliminating cancer stem cells in colorectal tumors.

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Argonne National Laboratory researchers have made new discoveries about the risks of prostate cancer in people with different genetic backgrounds.

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Below are some of the latest research and features on this growing population of older adults in the Seniors channel on Newswise.

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In JVSTB, researchers report successful results from a hand-held breast cancer screening device that can detect breast cancer biomarkers from a tiny sample of saliva.

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Chula researchers have developed a remarkable wireless hepatitis B virus test kit to screen for infection and collect data for an online database that’s fast and complete in one step.

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Sandalwood oil has been used worldwide for centuries. Now, a study is the first to demonstrate in vivo the chemo-preventive properties of a by-product of the oil in a mouse model. Results show administering alpha-santalol reduced visible prostate tumors, protected the normal tissue, and delayed progression from a precancerous condition to a high-grade form of cancer. These findings are significant because mortality in prostate cancer patients is mainly attributable to advanced stages of the disease.

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Patients with soft-tissue sarcoma treated with neoadjuvant, or pre-surgical, immunotherapy had very little residual tumor at the time of surgery and promising long-term survival, according to Phase II trial results published today in Nature Cancer by researchers at The University of Texas MD Anderson Cancer Center

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A specific combination of targeted therapy and immunotherapy may better help patients with non-small cell lung cancer (NSCLC) overcome inherent immune resistance and reinvigorate anti-tumor activity, according to a new study led by a researcher from The University of Texas MD Anderson Cancer Center.

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Findings from St. Jude Children’s Research Hospital showed a novel dual targeting approach, where a single molecule can recognize two potential cancer-related proteins, is more effective than the single targeting approach, preventing immune escape.

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The Department of Radiation Oncology at Cedars-Sinai Cancer has earned accreditation from the American Society for Radiation Oncology (ASTRO) Accreditation Program for Excellence.

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The UCLA team played a pivotal role in a clinical trial that led to the FDA granting accelerated approval of the first antibody drug conjugate (ADC), mirvetuximab soravtansine, for the treatment of platinum-resistant ovarian cancer.

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For decades, hormonal treatment of breast cancer has been going in one direction – blocking estrogen.

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Ovarian cancer is hard to diagnose in its early stages because it has vague symptoms, such as constipation, bloating, and back pain.

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For Black men with prostate cancer, racial representation is a key factor affecting trust in websites offering information on prostate cancer, reports a study in the March issue of The Journal of Urology®, an Official Journal of the American Urological Association (AUA).

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In a new article published in the Journal of Clinical Oncology, Moffitt Cancer Center researchers in collaboration with Sylvester Comprehensive Cancer Center and groups around the world share results from a novel model that can provide tailored predictions of how individual patients respond to different therapies.

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The company, based on science from the Hackensack Meridian Center for Discovery and Innovation, promises to capture biomarkers for early detection of disease

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For some leukemia patients, their only treatment option carries a risk of heart failure

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With a new $2 million federal grant, a researcher with the Case Western Reserve University School of Medicine will lead a team to further explore preliminary findings of an effective treatment for colorectal and possibly other cancers.

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A team of researchers from Wayne State University was awarded a $1.4 million, three-year grant from the U.S. Department of Defense for the study, “Cytochrome c acetylation drives prostate cancer aggressiveness and Warburg effect.”

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MD Anderso and C-Biomex today announced a strategic collaboration to co-develop CBT-001, a radioligand targeting the CA9 cancer biomarker.

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Established clinician researcher will focus on novel treatments and clinical trials for difficult-to-treat childhood cancers.

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The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention.

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Cedars-Sinai Cancer investigators have discovered a protein expressed on multiple myeloma cancer cells that drives disease growth and development. The new study found that blocking part of the protein’s unique signaling pathway stops myeloma growth in culture and in laboratory mice.

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Designing sensitive and single-use biosensors for early diagnosis remains a major challenge. Scientists in China invented submonolayer lasers on optical fibers as ultrasensitive and disposable biosensors.

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New prostate screening guidelines organized by the Prostate Cancer Foundation aim to address the longstanding health disparity in prostate cancer: Black men are diagnosed with and die from prostate cancer at a much higher rate than white men.

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New findings led by researchers at the American Cancer Society and the National Cancer Institute show more than one-third of cancer patients had a major adverse financial event – bankruptcy, lien, or eviction – before their cancer diagnosis.

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A study by a scientific team from the University of Vienna and the MedUni Vienna, recently published in the top-class journal Cellular & Molecular Immunology, has a promising result from tumor research: The enzyme phosphoglycerate dehydrogenase (PHDGH) acts as a metabolic checkpoint in the function of tumor-associated macrophages (TAMs) and thus on tumor growth. Targeting PHGDH to modulate the cancer-fighting immune system could be a new starting point in cancer treatment and improve the effectiveness of clinical immunotherapies.

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Some of the cancers that most often affect men are prostate, colorectal, lung, and skin cancers. Knowing about these cancers and what you can do to help prevent them or find them early (when they are small, haven't spread, and might be easier to treat) may help save your life.

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Through an analysis of tumor samples collected over time from patients with advanced melanoma, a Ludwig Cancer Research study has identified a set of preexisting conditions in tumors that predict whether such patients are likely to respond to a personalized immunotherapy known as adoptive T cell therapy (ACT) using tumor-infiltrating lymphocytes (TIL).

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Mahsa Dabagh is building a virtual model of a real human tumor, using data that characterizes the tissue on a molecular level.

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A recent American Academy of Dermatology survey revealed that nearly one in five adults are not aware that you can get sunburned during the winter, and even fewer protect themselves from the sun before common outdoor activities in cold weather.

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Through the use of artificial intelligence, teams hope to better check for diabetic retinopathy and improve the process of cervical cancer screenings

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In a recent study published in eClinicalMedicine, part of The Lancet Discovery Science, Moffitt Cancer Center researchers demonstrate that there is a significant unmet need for improved analyses and reporting of patient-reported outcomes in genitourinary cancer clinical trials.