Immunology Research News and Press Releases

When new COVID-19 vaccines were first administered two years ago, public health officials found an increase in cases of myocarditis, an inflammation of the heart muscle, particularly among young males who had been vaccinated with mRNA vaccines. It was unclear, however, what exactly was causing this reaction.

Research Results MEDICINE

VIDEO

Released: 5-May-2023 10:25 AM EDT

Video and transcript: Study of fecal microbiota on patients with C. diff infection

Newswise

The researcher discusses the findings in a new study on the efficacy and safety of fecal microbiota (REBYOTA™), the first microbiota-based live biotherapeutic approved by the US FDA used to prevent recurrent Clostridioides difficile infection in adults.

Research Results MEDICINE

3-May-2023 4:25 PM EDT

Study Identifies Messages about Vaccinating Children Against COVID-19 That Resonate Best with Vaccine-Hesitant Parents

Ann and Robert H. Lurie Children's Hospital of Chicago

A study from Ann & Robert H. Lurie Children’s Hospital of Chicago found that parents with children who were not yet vaccinated against COVID-19 were most likely to vaccinate their child after reading the following hypothetical scenario.

Research Results MEDICINE

Released: 4-May-2023 7:20 PM EDT

Gamma delta T cells can fight aggressive breast cancer

University of Freiburg

Researchers from the University of Frieburg discovered that coordinated differentiation and changes in the metabolism of breast cancer stem cells make them invisible for the immune system.

Research Results MEDICINE

Released: 4-May-2023 7:05 AM EDT

The Medical Minute: Crohn’s disease has no cure, but new treatments bring hope

Penn State Health

Anyone newly diagnosed with Crohn’s disease probably has some anxiety about having a chronic ailment for which there’s no cure. A Penn State Health doctor talks about how treatments and medication offer reason for hope.

Feature Expert MEDICINE

Released: 3-May-2023 5:55 PM EDT

Reviving exhausted T cells to tackle immunotherapy-resistant cancers

Sanford Burnham Prebys

One of the biggest goals of immunotherapy is to reverse T cell exhaustion to boost the immune system’s ability to destroy cancerous cells. Researchers at Sanford Burnham Prebys studying melanoma have found a new way to make this happen.

Research Results MEDICINE

Released: 3-May-2023 5:00 PM EDT

Stephen J. Galli, MD, to Receive 2024 American Society for Investigative Pathology Gold-Headed Cane Award

Federation of American Societies for Experimental Biology (FASEB)

The American Society for Investigative Pathology awards Stephen J. Galli, MD, the 2024 ASIP Gold-Headed Cane Award.

Announcement SCIENCE

Released: 3-May-2023 4:40 PM EDT

Digestive Disease Week 2023: Cedars-Sinai Experts Share Latest Research, Care Innovations

Cedars-Sinai

Digestive Disease Week (DDW) is the largest international gathering of physicians, researchers, and academics in the fields of gastroenterology, hepatology, endoscopy, and gastrointestinal surgery. DDW2023 will take place May 6-9 in Chicago and showcase 3,100 abstracts and hundreds of lectures on the latest advances in GI research, clinical practice and technology.

Research Tip Sheet MEDICINE

Released: 3-May-2023 3:15 PM EDT

Moffitt Researchers Develop CAR T Cells that Fight Prostate Cancer in Bone

Moffitt Cancer Center

Prostate cancer frequently metastasizes to the bone and is incurable. Moffitt Cancer Center researchers are working to identify new treatment options for this subset of patients. In a new article published today in Science Advances, a team of Moffitt scientists demonstrates that chimeric antigen receptor T-cell (CAR T) therapy is an effective antitumor approach in mouse models of bone metastatic prostate cancer.

Research Results MEDICINE

Expert Pitch

Expert Query

Expert Directory

Feature Channels: Immunology

Filters close

A combination of TLR9 and STING agonists induces potent neopeptide-specific T cell immunity and improves ICB efficacy in tumor models

Microanatomical lipid niche controls intestinal memory B cell migration and effector function

Pyruvate dehydrogenase operates as an intramolecular nitroxyl generator during macrophage metabolic reprogramming

Single cell RNA sequencing reveals heterogenous immune landscape of tumor infiltrated immune cell population against glioblastoma

Macrophages and neutrophils in lymph node granulomas from Mycobacterium tuberculosis-infected macaques have immunoregulatory phenotypes

Robust T cell responses to the Pfizer/BioNTech vaccine compared to infection and evidence of attenuated CD8+ T cell responses due to COVID-19

Oxidized phospholipid oxPAPC induces a dysfunctional Th1-like phenotype in regulatory T cells

Pro-resolution lipid mediator maresin-1 reduces inflammation, promotes neuroprotection, and prevents disease progression in multiple sclerosis model of autoimmunity

Cytometric analysis authenticates adjuvanticity of interferon-γ and suggests potential synergy with toll-like receptor agonists

Longitudinal analysis reveals age-dependent immune responses to SARS-CoV-2 infection in a mouse model

Effect of estrogen signaling in CD8 T cell mediated antiviral response

Engineering antibody fusion proteins for targeted intracellular therapeutic delivery

Design and characterization of a tumor-retained interleukin-2 cytokine/antibody fusion protein for cancer immunotherapy

A commensal-derived exopolysaccharide regulates ILC3-mediated diseases

Cross-reactive seasonal coronavirus antibody responses contribute to antibody- mediated effector functions against SARS-CoV-2 in individuals in Kenya

IL-1 signaling directs the prioritization of inflammatory sites in a model of postoperative pulmonary infection

Tunable dynamics of B cell selection in gut germinal centers

Premature Treg induction in early life results in FoxP3 instability post-weaning

Systems approaches to characterize the local heterogeneities in NK cell antitumor immunity in MHC I-disparate human non-small cell lung cancer

SARS-CoV-2 seroreversion is associated with a decrease in T cell functionality in children

Design and optimization of a novel proteomimetic polymer nanoplatform for the co-delivery of antigens with adjuvants

Tunable dynamics of B cell selection in gut germinal centers

Reshaping the anti-tumor CD4 T-cell repertoire contributes to oncolytic virus therapeutic efficacy in malignant glioma

The glucose transporter GLUT4 tethers RIG-I-like receptors to suppress antiviral immunity

Regulation of myeloid cells and inflammation marks increased susceptibility in a genetic model of acute viral infection-induced tissue damage

Bio-active lipids protect against immune-related adverse events due to immune checkpoint blockade therapy

Murine CD4+ T cells exhibit sexually dimorphic responses to estrogen signaling

Prenatally educated friendly NK cells regulate allo-specific T cell responses through expansion of Foxp3+CD4+Treg cells and suppression of Type 1 and 17 CD8+T cell responses

Dynamics of immune cells in the fetal brain upon viral inflammation

Overlapping Mendelian disorders of immunity and metabolism shape CD4+ T cell immunometabolism

Synergy between anti-commensal antibodies and IL-10 in gut homeostasis and disease

Inhibition of distinct glycolytic enzymes produces differential effects on CD4 T cell function

Diabetic wound keratinocytes induce macrophage JMJD3-mediated Nlrp3 expression via IL1R signaling

lntercellular mitochondria transfer rescues aerobic respiration in metabolically compromised macrophages in vitro and in vivo

Mitochondrial metabolic flexibility is critical for CD8 T cell anti-tumor immunity

Microanatomical lipid niche controls intestinal memory B cell migration and effector function

Reshaping the anti-tumor CD4 T-cell repertoire contributes to oncolytic virus therapeutic efficacy

Interferon-lambda accelerates viral clearance and regulates CD8+ T cells immunity in a murine model of SARS-CoV-2 infection

IL-10 promotes tissue-resident memory T cells (TRM) in the respiratory tract during SARS-CoV-2 infection in rhesus macaques

Pre-existing immunity modulates responses to mRNA boosters

Synthetically mannosylated antigens impair the antigen-specific humoral immune response and prolong the therapeutic efficacy of immunogenic protein drugs

Study reveals insights into post-vaccine heart inflammation cases

Video and transcript: Study of fecal microbiota on patients with C. diff infection

Study Identifies Messages about Vaccinating Children Against COVID-19 That Resonate Best with Vaccine-Hesitant Parents

Gamma delta T cells can fight aggressive breast cancer

The Medical Minute: Crohn’s disease has no cure, but new treatments bring hope

Reviving exhausted T cells to tackle immunotherapy-resistant cancers

Stephen J. Galli, MD, to Receive 2024 American Society for Investigative Pathology Gold-Headed Cane Award

Digestive Disease Week 2023: Cedars-Sinai Experts Share Latest Research, Care Innovations

Moffitt Researchers Develop CAR T Cells that Fight Prostate Cancer in Bone

Filters