The protein which helps the sperm and egg fuse together in sexual reproduction are part of a larger family of proteins that helps other cells bind together to create larger organs, and which also allows viruses like Zika and Dengue to invade healthy cells.
UAB names new leadership for Gorgas Center for Geographic Medicine.
If the last blast of winter has you longing for sun-soaked beaches in tropical locales, be sure to stop at the drug store for sunscreen and insect repellant before leaving for spring vacation.
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have uncovered the details behind the virus’s unique ability to cross the placental barrier and expose the fetus to a range of birth defects that often go beyond microcephaly to include eye and joint injury, and even other types of brain damage.
It’s been one year since the World Health Organization (WHO) declared Zika a public health emergency.The virus, transmitted through the Aedes aegypti mosquito, has since been declared to be a long-term problem rather than an emergency, but Zika continues to concern health professionals. At the Eck Institute for Global Health at the University of Notre Dame – a global leader in the study of Aedes aegypti – the vector-borne illness is one researchers hope to better understand.
Following the recent Zika outbreak in Miami-Dade County, a multidisciplinary team of physicians with the University of Miami Health System and Miller School of Medicine published a case study today in The New England Journal of Medicine, describing in detail the nation's first locally-transmitted case of Zika.
The Independent Citizens Oversight Committee of the California Institute for Regenerative Medicine (CIRM) has approved a pair of $2 million awards to University of California San Diego School of Medicine researchers to advance studies of new treatments for Zika virus infections and the use of stem cell-derived natural killer (NK) cells to target ovarian cancer and other malignancies.
Researchers identified a panel of small molecules that inhibit Zika virus infection, including one that stands out as a potent inhibitor of Zika viral entry into relevant human cell types. They screened a library of 2,000 bioactive compounds for their ability to block Zika virus infection in three distinct cell types using two strains of the virus.
Get the latest on Zika in the Zika Virus News Source
Even though the Zika virus hasn’t been in the news as much lately, it remains a serious public health concern.
The worst of the global Zika virus outbreak may be over but many key questions remain, such as why the virus persists in certain tissues after the systemic infection has cleared; how does the immune system counteract the virus and protect against reinfection; what determines the likelihood of long-term complications?
Mosquito surveillance efforts led by Iowa State University in 2016 found neither of the two species associated with the transmission of Zika virus. West Nile virus appeared more frequently in 2016 than it did in 2015.
Cornell and Weill Cornell Medicine researchers report on the use of biomaterials-based organoids in an attempt to reproduce immune-system events and gain a better understanding of B cells.
A new study has for the first time identified seven key proteins in the virus that may be the culprits behind this damage. The study is the first comprehensive description of the Zika virus genome.
Whitehead Institute researchers provide insight into a specific gene pathway that appears to regulate the growth, structure, and organization of the human cortex. They also demonstrate that 3D human cerebral organoids can be effective in modeling the molecular, cellular, and anatomical processes of human brain development.
Researchers at the Icahn School of Medicine at Mount Sinai are working on the basic science that lays the groundwork to finding a way to treat and prevent the Zika virus, a global health risk.
Aedes aegypti mosquitoes harboring parasitic Zika virus (ZIKV) are the primary transmitters of virus to humans, potentially causing catastrophic congenital microcephaly in babies born to women bitten by infected mosquitoes. But confirmation earlier this year by the Centers for Disease Control and Prevention (CDC) that ZIKV can also be sexually transmitted raised new alarm that virus could be passed between sexual partners in venues far from mosquito habitats.
Research finds that Zika-linked abnormalities that occur in human fetuses are more extensive and severe than previously thought, with 46 percent of 125 pregnancies among Zika-infected women resulting in birth defects in newborns or ending in fetal death.
According to the World Health Organization, Zika is no longer a global emergency. However, in South Texas, we now have the first case of Zika transmitted by mosquitoes locally. This is only the second state in the United States to report a case of local transmission of the disease.
As scientists race to create a vaccine for the Zika virus, new research from the University of Georgia suggests almost half of Americans wouldn’t be interested in getting the shot even if public health officials recommended it for them.
A Michigan State University research team is the first to show how a common bacterium found in improperly cooked chicken causes Guillain-Barre Syndrome, or GBS. The federally funded research, now published in the Journal of Autoimmunity, not only demonstrates how this food-borne bacterium, known as Campylobacter jejuni, triggers GBS, but offers new information for a cure.
A team of researchers, co-led by a University of California, Riverside professor, has found a long-sought-after mechanism in human cells that creates immunity to influenza A virus, which causes annual seasonal epidemics and occasional pandemics.
ASCB names 10 "Novel & Newsworthy" Honor abstracts out of 1263 being presented in San Francisco, Dec. 3-7
As the Zika epidemic spreads to the United States, the potential for contracting the disease via blood transfusion has emerged as a serious concern. The problem of transfusion-related Zika virus transmission—and recommended strategies to reduce that risk—are outlined in a special article in Anesthesia & Analgesia. Anesthesia & Analgesia is published by Wolters Kluwer.
The Bill & Melinda Gates Foundation has awarded an $8,777,578 million grant to The Wistar Institute to create a preventative Zika therapy utilizing synthetic DNA monoclonal antibodies (dMAbs).
While there are no cases of locally transmitted zika virus on the UF campus, Gainesville or Alachua County, Sharon Blansett, assistant to the associate vice president for UF student affairs, welcomes the mosquito traps as a virus-prevention measure for students living in graduate and family housing.
A team of scientists led by researchers at the University of Georgia has developed a new mouse model that closely mimics fetal brain abnormalities caused by the Zika virus in humans.
Mice with healthy immune systems could provide new insights into Zika virus pathology and treatment.
CHAPEL HILL, NC – Do you have questions about the Zika virus and how it spreads? If you’re traveling this holiday season, do you know how to protect yourself from Zika? Do you have questions about Zika and pregnancy? Do you know all the ways the virus can be transmitted? What about the likelihood of a Zika epidemic here in North Carolina?
There’s a war raging on a tiny battlefield and the outcome could well touch millions of people worldwide threatened by Zika and related viruses. The key ally unlocking the mystery surrounding this conflict is the long-dreaded yellow fever virus.
In this preclinical study, 100 percent of the animal models were protected from Zika after vaccination followed by a challenge with the Zika virus. In addition, they were protected from degeneration in the cerebral cortex and hippocampal areas of the brain, while the other cohort showed degeneration of the brain after Zika infection.
Outbreaks of the mosquito-borne disease chikungunya appear to be driven by infections centered in and around the home, with women significantly more likely to become ill, suggests new research from the Johns Hopkins Bloomberg School of Public Health, the Institut Pasteur in Paris and the International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b).
Researchers at Washington University School of Medicine in St. Louis and Vanderbilt University School of Medicine have identified a human antibody that prevents, in pregnant mice, the fetus from infection and the placenta from damage. The antibody also protects adult mice from Zika disease.
Researchers at Vanderbilt University Medical Center and Washington University School of Medicine in St. Louis, Missouri, have isolated a human monoclonal antibody that in a mouse model "markedly reduced" infection by the Zika virus.
Two researchers at the UNC School of Medicine have been named to a global consortium for Zika research and vaccine development.
The George Washington University School of Medicine and Health Sciences’ International Medicine Programs and Department of Microbiology, Immunology, and Tropical Medicine are co-sponsoring a two-day scientific research summit with the Instituto Butantan and Universidade de São Paulo focused on Zika virus.
Denver, Oct. 31, 2016 — The Harris County Public Health Department — which this past summer confirmed the state of Texas’ first Zika-associated death — has investigated nearly 600 suspected cases this year, 55 percent of which were pregnancy-related, according to new research released today at the American Public Health Association’s 2016 Annual Meeting in Denver.
As the Zika virus spreads locally in the continental United States, communities across the country have started thinking about mosquito control measures. Researchers at Texas A&M have created a type of mobile health technology to fight the mosquitos at their source: standing water.
La Jolla Institute for Allergy and Immunology (LJI) is among the 25 leading research and public health organizations from Latin America, North America, Africa, Asia, and Europe gathered in Recife for the launch of ZikaPLAN (Zika Preparedness Latin American Network). This global initiative, created in response to a Horizon 2020 funding call by the European Commission’s Directorate-General Research and Innovation, has been formed to address the Zika virus outbreak and the many research and public health challenges it poses.
Concerns over the Zika virus have focused on pregnant women due to mounting evidence that it causes brain abnormalities in developing fetuses. However, new research in mice from scientists at The Rockefeller University and La Jolla Institute for Allergy and Immunology suggests that certain adult brain cells may be vulnerable to infection as well.
Researchers at University of California San Diego School of Medicine have discovered that Zika virus infection leads to modifications of both viral and human genetic material. These modifications — chemical tags known as methyl groups — influence viral replication and the human immune response.
— The Arnhold Institute for Global Health at the Icahn School of Medicine at Mount Sinai, software company Dimagi, and Guatemalan NGO TulaSalud announced today that their partnership to locate and assess vulnerable areas in Guatemala to determine their level of risk for a Zika epidemic is being funded by the U.S. Agency for International Development (USAID).
In a study that could one day help eliminate the tragic birth defects caused by Zika virus, scientists from the Florida campus of The Scripps Research Institute (TSRI) have elucidated how the virus attacks the brains of newborns, information that could accelerate the development of treatments.
A collaborative study involving Kansas State University's Biosecurity Research Institute is providing Zika virus insight.
Understanding the full history the Zika virus along with new developments is key to getting a vaccine and medicine to prevent and relieve Zika infections. This includes knowing all the transmission methods--it's more than a mosquito bite.
Biologists sequencing the genome of the WO virus, which infects the bacterial parasite Wolbachia, have discovered that the phage carries DNA that produces black widow spider toxin: the first time an animal-like DNA has been found in such a virus.
Though first documented 70 years ago, the Zika virus was poorly understood when it burst onto the scene in the Americas in 2015. In one of the first and largest studies of its kind, a research team lead by virologists at Beth Israel Deaconess Medical Center (BIDMC) has characterized the progression of two strains of the viral infection. The study, published online this week in Nature Medicine, revealed Zika’s rapid infection of the brain and nervous tissues, and provided evidence of risk for person-to-person transmission.
In a collaborative effort with scientists at six Colombian hospitals, Johns Hopkins Medicine researchers report what they believe to be the strongest biological evidence to date linking Zika virus infection and Guillain-Barré syndrome.
A research team that includes scientists with Kansas State University's Biosecurity Research Institute has developed a promising Zika virus vaccine.
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