African American women participating in a clinical study on breast cancer had more side effects and poorer survival rates than did women of European ancestry, according to a an Indiana University study that identified ethnicity through genetics--a first in this type of research.
Researchers use compounds found in a combination plant-based diet to successfully prevent and treat ER-negative breast cancer in mice.
A new study suggests that the ability of a stem cell to differentiate into cardiac muscle (and by extension other cell types) depends on what portions of the genome are available for activation, which is controlled by the location of DNA in a cell’s nucleus.
More than 20 years after scientists revealed that mutations in the BRCA1 gene predispose women to breast cancer, Yale scientists have pinpointed the molecular mechanism that allows those mutations to wreak their havoc.
Mount Sinai researchers discover that insulinomas contain novel molecular pathways and reveal the map to regenerate insulin-producing cells
Scientists have helped provide a way to better understand how to enable drugs to enter the brain and how cancer cells make it past the blood brain barrier.
An existing drug may one day protect premenopausal women from life-altering infertility that commonly follows cancer treatments, according to a new study.
Sunbathers may want to avoid midnight snacks before catching some rays.
Drug zeroes in on mutated nuclear receptors found in cancer, leaves normal proteins alone
Black men who enrolled in patient navigator program at local barbershops were twice as likely to get colorectal cancer screening as those who did not.
Scientists have had limited success at identifying specific inherited genes associated with prostate cancer. Researchers at University of Utah Health studied prostate cancer patients with multiple cancer diagnoses to identify genetic mutations that may influence cancer treatment and cancer risk.
Research from the Stowers Institute provides evidence suggesting that cancer cells might streamline their genomes in order to proliferate more easily. The study, conducted in both human and mouse cells, shows that cancer genomes lose copies of repetitive sequences known as ribosomal DNA. While downsizing might enable these cells to replicate faster, it also seems to render them less able to withstand DNA damage.
Can use of hair products have an impact on breast cancer risk for women? That is a question explored by investigators from Rutgers Cancer Institute of New Jersey, Rutgers School of Public Health and other colleagues who examined use of hair dyes, hair relaxers and cholesterol-based hair products in African-American and Caucasian women.
A new study by UCLA scientists has found that the breakthrough immunotherapy drug pembrolizumab can be more effective in improving survival in people with non-small cell lung cancer (NSCLC) if they have previously received radiation therapy, compared to those without a history of radiation treatment.
A new technology generates cellular images detailed enough to distinguish cancerous from normal tissue. Researchers are working on speeding up the technology so it can be used during surgery, allowing surgeons to know if they have removed all the cancer while they still have time to take out more.
A new study suggests that the use of tomato — a key food of the Mediterranean diet — should be explored to develop supportive strategies against gastric cancer
A research team has engineered a small peptide that binds to a protein found in high-risk prostate cancers and can be imaged using MRI. The system identified aggressive tumors in mouse models of prostate cancer, and is a promising step for reliable early detection and treatment of high-risk, life-threatening prostate cancer.
Uninsured women with breast cancer were nearly 2.6 times more likely to have a late-stage diagnosis than cancer patients who were insured, finds a new study from the Brown School at Washington University in St. Louis.
In experiments with human colon cancer cells and mice, a team led by scientists at the Johns Hopkins Kimmel Cancer Center say they have evidence that cancer arises when a normal part of cells' machinery generally used to repair DNA damage is diverted from its usual task. The findings, if further studies confirm them, could lead to the identification of novel molecular targets for anticancer drugs or tests for cancer recurrence, the investigators say.
Of the 1,000 GI cancer patients seen at his clinic last year, nearly half were under age 50, says John L. Marshall, MD, director of the Ruesch Center for the Cure of Gastrointestinal Cancers at Georgetown Lombardi Comprehensive Cancer Center and chief of hematology and oncology at MedStar Georgetown University Hospital. Many are in their 20s and 30s; one was just 17.
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