Deep-learning technology developed by a team of Johns Hopkins engineers and cancer researchers can accurately predict cancer-related protein fragments that may trigger an immune system response. If validated in clinical trials, the technology could help scientists overcome a major hurdle to developing personalized immunotherapies and vaccines.
Nanozymes—artificial enzymes that can carry out pre-determined chemical reactions—could selectively activate a cancer drug within a tumor while minimizing damage to healthy tissue in a mouse model of triple negative breast cancer.
The bacterium commonly referred to as C. diff is sometimes called “C-difficult” because it is so hard to treat, said Mohamed Seleem, director of the Center for One Health Research. Seleem and Nectagen Inc. have received a nearly $275,000 grant from the National Institute of Allergy and Infectious Diseases to study whether synthetic proteins developed by Nectagen can reduce the toxicity of the digestive bacteria.
Safe drinking water is threatened globally by the increased toxicity of phytoplankton — or microscopic algae — blooms. The need for a better understanding of when and where the blooms will emerge spurred Virginia Tech researchers to start developing the first automated, real-time lake phytoplankton forecasting system. Working with the University of Florida, Virginia Tech faculty have been awarded a $2.
Two University of Texas at El Paso researchers have earned one of the nation’s highest awards for early-career faculty in 2023.
Dr. John Bennewitz, an assistant professor in the Department of Mechanical and Aerospace Engineering at The University of Alabama in Huntsville (UAH), has been awarded a $650,000, 45-month Air Force Office of Scientific Research (AFOSR) grant to develop an advanced propulsion system that will facilitate surveillance of space between the Earth and the Moon by the United States Space Force.
Everyone has scents that naturally appeal to them, such as vanilla or coffee, and scents that don’t appeal. What makes some smells appealing and others not? Researchers studied the behavior of the locusts and how the neurons in their brains responded to appealing and unappealing odors to learn more about how the brain encodes for preferences and how it learns.
A five-year, $3.1 million grant to study preventive strategies for sudden unexpected death in epilepsy (SUDEP) has been awarded to UTHealth Houston by the National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke.
UWF Center for Cybersecurity received a $2.5 million grant from the National Centers of Academic Excellence in Cybersecurity (NCAE-C) Program at the National Security Agency to expand the National Cybersecurity Workforce Development program, CyberSkills2Work.
An artificial intelligence (AI) platform could allow dentists and dental students to read radiograms (X-rays) with higher accuracy, helping them to better detect tooth decay and gum diseases.
A University of Oregon research team has landed a $3 million federal grant to work with Indigenous and rural communities in Oregon to find ways of reducing climate-changing carbon in the atmosphere in ways that build trust with historically marginalized groups.
New research from Q-MEEN-C shows that electrical stimuli passed between neighboring electrodes can also affect non-neighboring electrodes. Known as non-locality, this discovery is a crucial milestone toward creating brain-like computers with minimal energy requirements.
Today, the U.S. Department of Energy (DOE) announced $4.7 million in funding for five new research projects in computational biology. These projects will develop new software and analytical tools to manage the growing quantities of genomics and other data stemming from the study of microbes and other biological systems.
In 2021, 1.6 million Medicaid beneficiaries in North Carolina moved from a fee-for-service Medicaid model to a managed care system known as N.C. Medicaid Managed Care. What impact did the transition have on Medicaid enrollees who live in Forsyth County?
A $5 million grant from the Office of the Governor is funding the Arizona Wildfire Initiative (AZWI), an innovative new program at NAU aimed at ensuring the state of Arizona is better prepared for wildfire prevention, management and recovery.
The University of Miami Miller School of Medicine Department of Otolaryngology has received a new $3.2 million, five-year grant from the National Institutes of Health (NIH) to support their multidisciplinary translational research program on human genetic hearing loss (HL), a common sensory disorder affecting more than 28 million Americans.
Wildfires are causing a much greater warming effect than previously accounted. A new study focused on the role of “dark brown carbon” — an abundant but previously unknown class of particles emitted as part of wildfire smoke — highlights an urgent need to revise climate models and update approaches for the changing environment.
With funding from Virginia Catalyst, also known as the Virginia Biosciences Health Research Corp., Virginia Tech is engaged in three collaborative bioscience projects to address unmet health care needs in Virginia, according to Michael Friedlander, vice president for health sciences and technology at Virginia Tech. The Catalyst awards, which range from $350,000 to $800,000, support joint research projects between industry and Virginia universities that have the potential to significantly improve human health and create high value jobs in the commonwealth.
NYU Tandon School of Engineering researchers will develop new technologies to secure the “digital legal supply chain” — the processes by which official laws and legal information are recorded, stored, updated and distributed electronically — thanks to a $1.2 million grant just awarded by the National Science Foundation (NSF).
Researchers with Sylvester Comprehensive Cancer Center and collaborating organizations will study how new technology can help cancer patients manage symptoms and related stress from cancer treatment while at home.
The Rocky Mountain Center for Occupational and Environmental Health (RMCOEH), a partnership between the University of Utah and Weber State University and one of the nation’s leading centers focused on the health and safety of workers and their environment, was recently awarded an $8.6 million grant that will allow it to further a mission that touches tens of thousands of people each year in Utah and across the West.
The National Cancer Institute (NCI) has awarded a 5-year, $2.7 million grant to researchers at Sanford Burnham Prebys to investigate and elucidate the underlying cellular mechanisms that drive the most common form of breast cancer.
A first-of-its-kind analysis of historical DNA ties tens of thousands of living people to enslaved and free African Americans who labored at an iron forge in Maryland known as Catoctin Furnace soon after the founding of the United States. The study, spurred by groups seeking to restore ancestry knowledge to African American communities, provides a new way to complement genealogical, historical, bioarchaeological, and biochemical efforts to reconstruct the life histories of people omitted from written records and identify their present-day relatives.
Using a novel proteogenomic strategy and a variety of machine learning tools, investigators from the Icahn School of Medicine at Mount Sinai and colleagues have identified a 64-protein signature that may predict a subset of ovarian cancer patients who are unlikely to respond to chemotherapy. The multicenter study, published online August 3 in Cell, reports on a pioneering analysis of chemo-refractoriness in high-grade serous ovarian cancer (HGSOC). The work also implicates possible therapeutic targets for these patients.
In a first, scientists define five types of colon neurons specialized for sending different signals to the brain.
Argonne obtains DOE funding for three transformative clean energy projects, revolutionizing geothermal power plants, advancing safety analysis for advanced nuclear reactors and driving the commercialization of used nuclear fuel recycling.
In a new preclinical study from Wake Forest University School of Medicine, scientists provide the first evidence that changes in the gut microbiome have significant effects on cocaine use and cravings after withdrawal.
Susan G. Komen®, the world’s leading breast cancer organization, today announced the renaming of a metastatic breast cancer (MBC) grant to honor Rhonda Crocker Howell, a Raleigh resident, community leader and dedicated breast cancer advocate. The grant will be renamed The Susan G. Komen Metastatic Breast Cancer Collaborative Research Grant in honor of Rhonda Crocker Howell.
Researchers at Vanderbilt University Medical Center have received a four-year, $28 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health, to study the relationship between COVID-19 and diabetes.
Suvranu De, dean of the FAMU-FSU College of Engineering, is building a better simulator — one that uses brain stimulation to improve learning for physicians undergoing training for robotic surgeries for oral cancers.
A multi-university study will investigate the aftermath of the train derailment and subsequent chemical spill and fires in East Palestine, Ohio, to gain a better understanding of the impact that this event had on the community.
Cedars-Sinai Cancer investigators are spearheading a project, funded by a five-year, $11.2 million grant from the National Cancer Institute, part of the National Institutes of Health, to advance scientific knowledge of how biological differences between men and women affect bladder cancer.
Florida Public Archaeology Network, a program of #UWF, has received a $99,968 grant from the National Oceanic and Atmospheric Administration (NOAA) National Estuarine Research Reserve System Science Collaborative.
Molecules that act as connected wheels can hold long molecular chains together to modify the properties of soft polymers.
Artificial intelligence has entered the mainstream in a way the world has never experienced before. Millions of people are using tools such as ChatGPT and Stable Diffusion for AI-generated help answering questions, creating images and accomplishing a host of other tasks. The Office of Naval Research has awarded Parisa Kordjamshidi, an assistant professor in the Department of Computer Science and Engineering at Michigan State University and her colleagues a $1.8 million grant to make our interactions with AI more reasonable and reliable. This would bolster the confidence people have in using AI tools that are increasingly acting as digital assistants. But the team also has larger goals.
A Penn Medicine and Children’s Hospital of Philadelphia (CHOP) team will seek to develop treatments for three rare, incurable genetic diseases with the help of a $26 million grant from the National Institutes of Health (NIH).
A spinal cord injury is a life-altering event, and the effects, such as muscle weakness and paralysis, can dramatically disrupt a person’s life. While there is no cure for paralysis, there has been some progress in developing potential treatment options to improve symptoms. Still, much of it remains out of reach to many patients.
A team including University of Pittsburgh researchers uses computer modeling and new ways of employing enzymes to create never-before-seen amino acids.
Photonic crystal structures have excellent light control properties and are hot topics in the field of photonics. For the preparation of photonic crystal structures with nanoscale three-dimensional spatial resolution inside the crystal, new femtosecond laser processing technologies are urgently needed. Scientists in China proposed a photonic crystal structure fabrication method based on nanoscale femtosecond laser multi-beam lithography. The technique will open possible ways to fabricate nanostructures for applications in optical communication and light manipulation.
Psychosocial stress profoundly affects people’s lives globally, not least because it can be a critical risk factor for cardiovascular disease. Thanks to an $11.5 million award renewal from the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health, distinguished researchers at the Icahn School of Medicine at Mount Sinai and elsewhere aim to gain a deeper understanding of how stress influences cardiovascular health.
“We’re situated in a unique position to address the growing cancer burden among the Hispanic community,” said Dr. Lakshmanaswamy, a biomedical science professor who directs the university’s Center of Emphasis in Cancer. “Our goal is to improve access to health care for our Hispanic community members by developing novel biomarkers and therapeutics, grounded in an improved understanding of the biological, cultural and behavioral determinants of cancer."
The American Neuromuscular Foundation, is excited to announce Jerry R. Mendell, MD, as the recipient of the 2023 Best Abstract Award, for his abstract titled, “Long-Term Safety and Efficacy in Patients With Duchenne Muscular Dystrophy 4 Years Post-Treatment With Delandistrogene Moxeparvovec in a Phase 1/2a Study.”
A metabolic by-product that is more prevalent during fasting may supercharge immune cells as they fight infection and disease, reports an early stage study by Van Andel Institute scientists and collaborators.
According to the National Kidney Foundation, more than 100,000 Americans are waiting for a kidney transplant, and the demand for donated kidneys far exceeds the supply. In fact, only 25,498 kidney transplants were performed in 2022, and kidney disease impacts 37 million people in the U.S. But a new preclinical study, led by scientists at Wake Forest University School of Medicine, shows that a new technology called mitochondrial transplantation holds promise as a potential therapy that could change the kidney transplant landscape.
The award will support Kayser's research on engineering devices for assistive soft robotics and tactile displays.
Two decades ago, the Practice Environment Scale of the Nursing Work Index was published to measure the nursing practice environment. Although the instrument's use has resulted in advances in science and quality improvement efforts, its potential may be limited by the availability and quality of translations into different languages.
Investigators at the Icahn School of Medicine at Mount Sinai have designed an innovative RNA-based strategy to activate dendritic cells—which play a key role in immune response—that eradicated tumors and prevented their recurrence in mouse models of melanoma.
Researchers have developed methods to study and manipulate areas of the brain, though many of those methods are restricted by the limited depth that light can reach within the brain. A multidisciplinary team at Washington University in St. Louis plans to overcome that limitation by integrating ultrasound with genetics to precisely modify neurons in the brain.
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