Research Alert
Newswise — Herdy et al. identify an enriched population of senescent neurons in the Alzheimer’s brain, which can be modeled in vitro using induced neurons (iNs) and eliminated with senotherapeutics. Alzheimer’s iNs present molecular and genetic markers of senescence and an inflammatory secretome that can trigger reactive astrogliosis.
MEDIA CONTACT
Register for reporter access to contact detailsCITATIONS
DOI link; Publisher Website; Download PDF