The FDA announced on Aug 4 2009 that tumor necrosis factor (TNF) blockers used in the treatment of immune disorders carry an increased risk of lymphoma and other cancers in children and adolescents. The discoverer of TNF-alpha, Lloyd J. Old, M.D., a tumor immunologist, is available for comment.
Dendreon's PROVENGE for the treatment of advanced prostate cancer is the first active cellular immunotherapy to prolong patient survival, according to data from a pivotal phase III clinical trial announced at yesterday's AUA annual meeting in Chicago. This milestone achievement for the field of tumor immunology heralds the advent of a new dawn in cancer therapy, say experts, where immune-based agents will form a new, fourth modality to complement today's standard chemical, radiological, and surgical therapies.
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