Latest News from: St. Jude Children's Research Hospital

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Newswise: St. Jude Appoints Leading Scientist to Create Groundbreaking Center of Excellence for Structural Cell Biology
Released: 21-Nov-2024 3:15 PM EST
St. Jude Appoints Leading Scientist to Create Groundbreaking Center of Excellence for Structural Cell Biology
St. Jude Children's Research Hospital

Georgios Skiniotis, PhD, to develop and lead new center focusing on advanced imaging techniques, including cryo-ET.

Newswise: Glutamine Metabolic Switch Is Key to Red Blood Cell Development and Disease
Released: 15-Nov-2024 10:45 AM EST
Glutamine Metabolic Switch Is Key to Red Blood Cell Development and Disease
St. Jude Children's Research Hospital

Scientists at St. Jude Children’s Research Hospital identified a link between glutamine metabolism and red blood cell maturation, showing how disruption of the process can drive disease.

Newswise: Tumor Suppressor Forms Gel-Like Assemblies to Sacrifice Cancer Cells
Released: 11-Nov-2024 2:30 PM EST
Tumor Suppressor Forms Gel-Like Assemblies to Sacrifice Cancer Cells
St. Jude Children's Research Hospital

Scientists at St. Jude Children’s Research Hospital have uncovered a previously unrecognized tumor suppression mechanism through the study of condensates and ribosome formation.

Newswise: Mitchell Weiss of St. Jude Children’s Research Hospital elected to the National Academy of Medicine
Released: 24-Oct-2024 10:00 AM EDT
Mitchell Weiss of St. Jude Children’s Research Hospital elected to the National Academy of Medicine
St. Jude Children's Research Hospital

Leading expert in catastrophic blood disorders becomes the seventh St. Jude faculty member tapped for this honor.

Newswise: St. Jude ranks in top 10 of U.S. News Best Children's Hospitals for Cancer
Released: 9-Oct-2024 4:30 PM EDT
St. Jude ranks in top 10 of U.S. News Best Children's Hospitals for Cancer
St. Jude Children's Research Hospital

St. Jude Children’s Research Hospital was recognized as one of the top 10 pediatric cancer hospitals for the 17th straight year by U.S. News & World Report. Every year since 2008, the publication has evaluated about 100 hospitals with pediatric oncology programs and ranked the top 50 as part of its annual list of Best Children’s Hospitals.

Newswise: St. Jude Names M. Madan Babu, PhD, Senior Vice President and Chief Data Scientist
Released: 1-Oct-2024 12:20 PM EDT
St. Jude Names M. Madan Babu, PhD, Senior Vice President and Chief Data Scientist
St. Jude Children's Research Hospital

In his new role, Babu will bring new, advanced computing technologies and data science approaches to biomedical research. His team will also facilitate the integration of biological and biomedical data, foster a data science research culture, and build international collaborations.

Newswise: Structure of a Eukaryotic CRISPR-Cas homolog, Fanzor2, Shows Its Promise for Gene Editing
Released: 1-Oct-2024 12:05 PM EDT
Structure of a Eukaryotic CRISPR-Cas homolog, Fanzor2, Shows Its Promise for Gene Editing
St. Jude Children's Research Hospital

See how structures of Fanzor2, a relation of the transposon family TnpB, show how the protein can be used in genome engineering technology like CRISPR-Cas9.

   
Newswise: Clinical Trial Results Show Low-Intensity Therapy Can Achieve Positive Outcomes for Certain Pediatric Leukemia Subtypes
Released: 24-Sep-2024 4:05 PM EDT
Clinical Trial Results Show Low-Intensity Therapy Can Achieve Positive Outcomes for Certain Pediatric Leukemia Subtypes
St. Jude Children's Research Hospital

Using genomics and early treatment response to guide risk-stratification and low-intensity therapy use for ETV6::RUNX1 and high-hyperdiploid B-cell acute lymphoblastic leukemia benefits patients.

Newswise: Urate Transporter Structures Reveal the Mechanism Behind Important Drug Target for Gout
Released: 9-Sep-2024 11:05 AM EDT
Urate Transporter Structures Reveal the Mechanism Behind Important Drug Target for Gout
St. Jude Children's Research Hospital

Ten structures of URAT1 obtained by scientists at St. Jude Children’s Research Hospital provide a deep understanding of the mechanism of urate transport to guide gout therapeutic design.

Newswise: Early interventions may improve long-term academic achievement in young childhood brain tumor survivors
Released: 21-Aug-2024 12:05 PM EDT
Early interventions may improve long-term academic achievement in young childhood brain tumor survivors
St. Jude Children's Research Hospital

Scientists at St. Jude Children’s Research Hospital found infants and young children treated for brain tumors fell behind early in academic readiness, which predicted falling behind in later school years.

Newswise: T helper cells may be the key to improving annual influenza vaccines
Released: 20-Aug-2024 10:05 AM EDT
T helper cells may be the key to improving annual influenza vaccines
St. Jude Children's Research Hospital

The annual influenza vaccination provides updated protection against the virus but could be improved as there is large variability in its efficacy.

Newswise: Study reveals oleoyl-ACP-hydrolase underpins lethal respiratory viral disease
Released: 12-Aug-2024 1:30 PM EDT
Study reveals oleoyl-ACP-hydrolase underpins lethal respiratory viral disease
St. Jude Children's Research Hospital

Respiratory infections can be severe, even deadly, in some individuals, but not in others. Scientists at St. Jude Children’s Research Hospital, the Peter Doherty Institute for Infection and Immunity and other collaborators have gained new understanding of why this is the case by uncovering an early molecular driver that underpins fatal disease.

Newswise: Scientists identify genes linked to relapse in the most common form of childhood leukemia
Released: 12-Aug-2024 11:50 AM EDT
Scientists identify genes linked to relapse in the most common form of childhood leukemia
St. Jude Children's Research Hospital

Scientists from St. Jude Children’s Research Hospital, Seattle Children’s and the Children’s Oncology Group (COG) have identified novel genetic variations that influence relapse risk in children with standard risk B-cell acute lymphoblastic leukemia (SR B-ALL), the most common childhood cancer.

Newswise: St. Jude identifies SARS-CoV-2 “mimic” contributing to pediatric inflammatory syndrome
Released: 7-Aug-2024 1:05 PM EDT
St. Jude identifies SARS-CoV-2 “mimic” contributing to pediatric inflammatory syndrome
St. Jude Children's Research Hospital

Discover St. Jude research from Paul Thomas, PhD, linking SARS-CoV-2 infections and molecular mimicry with multisystem inflammatory syndrome in children.

Newswise: Genetic ‘episignatures’ guide researchers in identifying causes of unsolved epileptic neurological disorders
Released: 6-Aug-2024 3:05 PM EDT
Genetic ‘episignatures’ guide researchers in identifying causes of unsolved epileptic neurological disorders
St. Jude Children's Research Hospital

Scientists at St. Jude Children’s Research Hospital use DNA methylation patterns as a roadmap for identifying causes of severe epilepsies in children.

Newswise: Age impacts pharmacogenomics and treatment outcomes for most common form of leukemia
Released: 5-Aug-2024 5:05 PM EDT
Age impacts pharmacogenomics and treatment outcomes for most common form of leukemia
St. Jude Children's Research Hospital

Explore how scientists at St. Jude Children’s Research Hospital have identified causes for age-related differences in treatment outcomes of B-cell acute lymphoblastic leukemia.

Newswise: Improved chemokine homing enhances CAR T–cell therapy for osteosarcoma
Released: 5-Aug-2024 12:05 PM EDT
Improved chemokine homing enhances CAR T–cell therapy for osteosarcoma
St. Jude Children's Research Hospital

Learn how scientists at St. Jude are leading research to improve CAR T-cell therapy for osteosarcoma by enhancing chemokine homing.

Newswise: Serotonin uptake regulates ependymoma tumor growth
Released: 31-Jul-2024 2:05 PM EDT
Serotonin uptake regulates ependymoma tumor growth
St. Jude Children's Research Hospital

St. Jude Children’s Research Hospital and Baylor College of Medicine have implicated the neurotransmitter serotonin in ependymoma tumor growth, suggesting a new class of drugs to test against these tumors.

Newswise: Biomolecular condensate ‘molecular putty’ properties found encoded in protein sequence
Released: 2-Jul-2024 12:05 PM EDT
Biomolecular condensate ‘molecular putty’ properties found encoded in protein sequence
St. Jude Children's Research Hospital

Scientists at St. Jude Children’s Research Hospital, the State University of New York at Buffalo and Washington University at St. Louis probed how condensates behave like viscoelastic putty and age to more solid states.

Newswise: Master autoimmune regulator gets by with a little help from its friends
Released: 27-Jun-2024 1:05 PM EDT
Master autoimmune regulator gets by with a little help from its friends
St. Jude Children's Research Hospital

See how St. Jude researchers investigated Foxp3 function as a transcription cofactor in regulatory T cells in immune system activation and suppression.



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