Latest News from: Van Andel Institute

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Newswise: Experimental Blood Test Improves Early Detection of Pancreatic Cancer
Released: 4-Oct-2024 1:05 PM EDT
Experimental Blood Test Improves Early Detection of Pancreatic Cancer
Van Andel Institute

An experimental blood test detects early-stage pancreatic cancer more effectively than other available tests, reports a new study published in Cancer Letters.

Newswise: New anti-cancer ‘degrader’ targets protein essential to infant leukemia
Released: 29-Aug-2024 3:05 PM EDT
New anti-cancer ‘degrader’ targets protein essential to infant leukemia
Van Andel Institute

Scientists have developed a potent anti-cancer compound that inhibits cancer cell growth in a tough-to-treat type of infant leukemia.

Newswise: Immune cells have a metabolic backup plan for accessing their anti-cancer playbook
Released: 23-Aug-2024 10:05 AM EDT
Immune cells have a metabolic backup plan for accessing their anti-cancer playbook
Van Andel Institute

Immune cells use two different routes to produce acetyl-CoA, an essential metabolite required to fight infection and cancer, reports a study led by Van Andel Institute scientists.

Newswise:Video Embedded when-it-comes-to-dna-replication-humans-and-baker-s-yeast-are-more-alike-than-different
VIDEO
30-Jul-2024 11:05 AM EDT
When it comes to DNA replication, humans and baker’s yeast are more alike than different
Van Andel Institute

Humans and baker’s yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies published in the journals Science and Proceedings of the National Academy of Sciences.

   
Newswise: Study finds persistent proteins may influence metabolomics results
Released: 18-Jul-2024 11:40 AM EDT
Study finds persistent proteins may influence metabolomics results
Van Andel Institute

Van Andel Institute scientists have identified more than 1,000 previously undetected proteins in common metabolite samples, which persist despite extraction methods designed to weed them out.

Newswise:Video Embedded heating-proteins-to-body-temperature-reveals-new-drug-targets
VIDEO
Released: 15-May-2024 12:05 PM EDT
Heating proteins to body temperature reveals new drug targets
Van Andel Institute

Some proteins shift their shape when exposed to different temperatures, revealing previously unknown binding sites for medications.

Newswise: Scientists identify cell vulnerability ‘fingerprint’ related to Parkinson’s, Lewy body dementia
Released: 16-Apr-2024 2:05 PM EDT
Scientists identify cell vulnerability ‘fingerprint’ related to Parkinson’s, Lewy body dementia
Van Andel Institute

A new study offers a first look into the complex molecular changes that occur in brain cells with Lewy bodies, which are key pathological hallmarks of Parkinson’s disease and some dementias.

Newswise: Combining Epigenetic Cancer Medications May Have Benefit for Colorectal Cancers and Other Tumor Types
27-Mar-2024 1:30 PM EDT
Combining Epigenetic Cancer Medications May Have Benefit for Colorectal Cancers and Other Tumor Types
Van Andel Institute

A pair of medications that make malignant cells act as if they have a virus could hold new promise for treating colorectal cancers and other solid tumors, reports a study published today in Science Advances.

Newswise: Inflammation and loss of protective mechanisms in the brain linked to suicide risk
Released: 14-Nov-2023 11:05 AM EST
Inflammation and loss of protective mechanisms in the brain linked to suicide risk
Van Andel Institute

A first-of-its-kind study has identified overactive inflammation and loss of critical protection mechanisms in the brain as potential contributors to suicide risk.

   
Newswise: Van Andel Institute scientist awarded $2.9 million to tackle insulin resistance, a driver of Type 2 diabetes
Released: 3-Oct-2023 10:05 AM EDT
Van Andel Institute scientist awarded $2.9 million to tackle insulin resistance, a driver of Type 2 diabetes
Van Andel Institute

Nick Burton, Ph.D., has earned a five-year, nearly $2.9 million New Innovator Award from the National Institutes of Health Common Fund to find new ways to fix or prevent insulin resistance, a key driver of Type 2 diabetes.

Newswise: Van Andel Institute chief scientist earns $7.9 million Outstanding Investigator Award to support cancer research
Released: 28-Sep-2023 1:05 PM EDT
Van Andel Institute chief scientist earns $7.9 million Outstanding Investigator Award to support cancer research
Van Andel Institute

Van Andel Institute Chief Scientific Officer Peter A. Jones, Ph.D., D.Sc. (hon), has received a seven-year, nearly $7.9 million grant from the National Cancer Institute’s Outstanding Investigator Award program.

Newswise: Van Andel Institute appoints new Graduate School dean and chief academic officer
Released: 26-Sep-2023 4:05 PM EDT
Van Andel Institute appoints new Graduate School dean and chief academic officer
Van Andel Institute

Van Andel Institute has appointed Eric Swindell, Ph.D., as dean and chief academic officer of Van Andel Institute Graduate School, effective Dec. 4, 2023.

Newswise: Study illuminates mechanism that annotates genetic information passed from fathers to offspring
6-Sep-2023 2:30 PM EDT
Study illuminates mechanism that annotates genetic information passed from fathers to offspring
Van Andel Institute

Van Andel Institute scientists and collaborators have identified a key part of a mechanism that annotates genetic information before it is passed from fathers to their offspring.

Newswise: Van Andel Institute scientist nets $2.4 million award to study ‘cellular powerhouses’
Released: 30-Aug-2023 2:05 PM EDT
Van Andel Institute scientist nets $2.4 million award to study ‘cellular powerhouses’
Van Andel Institute

Our cells are powered by tiny “powerplants” called mitochondria, which transform nutrients into fuel that sustains life. But there’s more to the story of mitochondria, says Van Andel Institute Assistant Professor Sara Nowinski, Ph.D.

Newswise: Repairing broken brain circuits may offer path to new Parkinson’s treatments
Released: 24-Aug-2023 11:05 AM EDT
Repairing broken brain circuits may offer path to new Parkinson’s treatments
Van Andel Institute

Scientists have identified a series of processes that help the brain adapt to damage caused by breakdowns in circuits that govern movement, cognition and sensory perception.

Newswise: Alternative cellular ‘fuels’ boost immunity
Released: 28-Jul-2023 11:05 AM EDT
Alternative cellular ‘fuels’ boost immunity
Van Andel Institute

A metabolic by-product that is more prevalent during fasting may supercharge immune cells as they fight infection and disease, reports an early stage study by Van Andel Institute scientists and collaborators.

Newswise: Breakdown of ‘protective mechanisms’ can drive lung cancer development
Released: 22-Jun-2023 10:45 AM EDT
Breakdown of ‘protective mechanisms’ can drive lung cancer development
Van Andel Institute

Loss of two key “protector” proteins initiates epigenetic changes that transform healthy lung cells into cancerous ones, according to new research from Van Andel Institute scientists.

Newswise: Targeting uncontrolled inflammation may hold the key to treating therapy-resistant cancers
Released: 11-May-2023 1:15 PM EDT
Targeting uncontrolled inflammation may hold the key to treating therapy-resistant cancers
Van Andel Institute

Van Andel Institute scientists have pinpointed how a specific gene mutation triggers an inflammatory cascade that may drive development of treatment-resistant cancers.

Newswise: Van Andel Institute, Washington University School of Medicine in St. Louis to lead genome center under $140M NIH initiative
Released: 11-May-2023 1:10 PM EDT
Van Andel Institute, Washington University School of Medicine in St. Louis to lead genome center under $140M NIH initiative
Van Andel Institute

Van Andel Institute’s Hui Shen, Ph.D., and Washington University School of Medicine in St. Louis’s Ting Wang, Ph.D., will co-lead a collaborative project supported by the Somatic Mosaicism across Human Tissues (SMaHT) Network, a new $140 million National Institutes of Health-led effort to better understand the genetic differences between individual cells and tissues in the body.

   
Newswise: Osteoporosis treatments may benefit from discovery of key driver of low bone density
Released: 19-Apr-2023 11:05 AM EDT
Osteoporosis treatments may benefit from discovery of key driver of low bone density
Van Andel Institute

Scientists have pinpointed a key driver of low bone density, a discovery that may lead to improved treatments with fewer side effects for women with osteoporosis.



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