COVID-19 reshaped mobility patterns worldwide, affecting walking, driving and public transit use, finds a new study published in The Lancet Public Health. The research, led by an international team including researchers in the Brown School at Washington University in St. Louis, analyzed data from nearly 300 cities to understand how urban transportation habits adapted during the pandemic.
Researchers at WashU Medicine shrink gastrointestinal tumors in mice using a yeast probiotic to deliver immunotherapy to the gut, offering a potentially novel strategy to target hard-to-reach gut cancers.
Brain science researchers at Washington University in St. Louis are studying how the brain perceives, processes, and remembers everyday events.
Researchers at Washington University School of Medicine in St. Louis have used AI tools to describe three sub-types of Chiari type-1 malformation, which will help guide clinicians to make the most effective treatment decisions for their patients. Chiari type-1 malformation is a condition in which the cerebellum extends beyond the gap in the skull where it connects to the spinal cord.
Researchers at Washington University School of Medicine in St. Louis have linked disease-related proteins and genes to identify specific cellular pathways responsible for Alzheimer’s genesis and progression. The proteins were gathered from cerebrospinal fluid and are a good proxy for activity in the brain. Several of them may be potential targets for therapies.
Joshua Yuan, Susie Dai and colleagues at Washington University and Texas A&M create biodiesel with electrocatalysis and bioconversion.
A small clinical trial shows promising results for patients with triple-negative breast cancer who received an investigational vaccine designed to prevent recurrence of tumors. Conducted at Washington University School of Medicine in St. Louis with a therapy designed by WashU Medicine researchers, the trial is the first to report results for this type of vaccine — known as a neoantigen DNA vaccine — for breast cancer patients.
If there is one thing that is constant in marketing, it's that things are constantly changing, according to Michael Wall, a marketing expert at WashU Olin Business School. As social media users flock to sites that align with their political beliefs, brands face the challenge of connecting with diverse audiences.
Washington University School of Medicine in St. Louis and BJC Health System have launched the joint Center for Health AI. The center will focus on making care more personalized and effective for patients and more efficient and manageable for physicians, nurses and all those striving to ensure patients receive the very best care.
Researchers at WashU Medicine have identified a possible way to make glioblastoma cells vulnerable to different types of immunotherapy. The strategy, which they demonstrated in cells in the lab, forces brain cancer cells to display targets for the immune system to attack. Their study was published in Nature Genetics.
WashU biologists, led by Xuehua Zhong in Arts & Sciences, investigated the inner workings of DNA methylation in plants. Their findings could help engineer crops that are more resilient to environmental changes, like heat or drought stress.
Researchers at WashU Medicine collaborated with an international team of doctors and scientists to identify the cause of a rare disorder involving intellectual disability and brain malformations. The team found a link between the child’s neurological symptoms and a genetic change that affects how proteins are properly folded within cells, providing the parents with a molecular diagnosis and identifying an entirely new type of genetic disorder. The findings are published in Science.
Researchers at WashU Medicine have found a process by which the brain guards against attack by the immune system. In mice with multiple sclerosis, such "guardian" proteins that train the immune system were drastically depleted, and replenishing them improved symptoms, according to a study in Nature.
A new analysis led by researchers at Washington University School of Medicine in St. Louis has revealed detailed 3D maps of the internal structures of multiple tumor types. These cancer atlases reveal how different tumor cells — and the cells of a tumor’s surrounding environment — are organized, in 3D, and how that organization changes when a tumor spreads to other organs. The detailed findings offer scientists valuable blueprints of tumors that could lead to new approaches to therapy and spark a new era in the field of cancer biology, according to the researchers.
Enrollment in Medicaid was associated with higher risk of death from a central nervous system (CNS) tumor, with an almost two-fold higher risk for young CNS tumor patients enrolled at diagnosis, finds a study from the Brown School at Washington University in St. Louis.
Researchers at Washington University School of Medicine in St. Louis have identified potentially far-reaching effects of a particular gut bacterium that was linked to better growth in Bangladeshi children receiving a therapeutic food designed to nurture healthy gut microbes. The far-reaching effects include regulating appetite, immune responses, neuronal function, and the ability of pathogenic bacteria to produce disease.
Researchers from WashU Medicine and Northwestern University developed an implantable device that can detect an overdose and rapidly deliver naloxone.
In a new publication, engineers at Washington University in St. Louis make the case for electro-agriculture to help drastically cut carbon emissions.
Researchers at WashU Medicine have reduced scar formation and improved heart function in mouse models of heart failure using a monoclonal antibody treatment, similar to one approved by the FDA for other conditions. The findings point to the possibility of developing such immunotherapies for heart failure in patients who have experienced a heart attack or other injury.
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