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A study by researchers at the Icahn School of Medicine at Mount Sinai has identified strategies for using large language models (LLMs), a type of artificial intelligence (AI), in health systems while maintaining cost efficiency and performance. The findings, published in the November 18 online issue of npj Digital Medicine, provide insights into how health systems can leverage advanced AI tools to automate tasks efficiently, saving time and reducing operational costs while ensuring these models remain reliable even under high task loads.

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A team of clinicians, scientists, and engineers at Mount Sinai trained a deep learning pose-recognition algorithm on video feeds of infants in the neonatal intensive care unit (NICU) to accurately track their movements and identify key neurologic metrics.

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Health System to serve as a lead core enrollment site for diverse, national health database

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Mount Sinai researchers have discovered for the first time a neural mechanism for memory integration that stretches across both time and personal experience.

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Expanded protocols promote early detection in high-risk patients and prevent hospital outbreaks of Candida auris

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Mount Sinai study shows how the heart and brain interact to influence sleep patterns and help with recovery

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Researchers at the Icahn School of Medicine at Mount Sinai have discovered a way that ovarian cancer tumors manipulate their environment to resist immunotherapy and identified a drug target that could overcome that resistance. The study, published in the October 30 online issue of Cell used a cutting-edge spatial genomics technology and preclinical animal models, with tumor specimens from ovarian cancer patients further validating the findings. They found that ovarian cancer cells produce a molecule called Interleukin-4 (IL-4), which is typically associated with asthma and the skin condition eczema, also known as atopic dermatitis. The study went on to find that the cancer cells used IL-4 to create a protective environment that kept away killer immune cells, making the tumors resistant to immunotherapy. A drug, dupilumab, which blocks IL-4’s activity, has been approved by the Food and Drug Administration (FDA) and is already used to treat asthma and eczema. This new study suggests dupi

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The Icahn School of Medicine at Mount Sinai will award its 2024 Maria I. New International Prize for Biomedical Research to Christine E. Seidman, MD, for her pioneering work in cardiovascular genetics, which has transformed the understanding of congenital heart disease and diseases that cause thickening or weakening of the heart muscles. The prize honors medical innovators in the tradition of the late Maria I. New, MD, a world-renowned researcher in pediatric genetic disorders with a special focus on endocrinology throughout her six-decade career. Dr. Seidman will receive a prize of $20,000 and will present the Maria I. New Distinguished Lecture during a ceremony to be held at Icahn Mount Sinai in New York City on Friday, November 8.

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Scientists at the Icahn School of Medicine at Mount Sinai, in collaboration with colleagues in the field, have developed an innovative antibody platform aimed at tackling one of the greatest challenges in treating rapidly evolving viruses like SARS-CoV-2: their ability to mutate and evade existing vaccines and therapies. Their findings, including preclinical studies in mice, introduce the Adaptive Multi-Epitope Targeting and Avidity-Enhanced (AMETA) Nanobody Platform, a new antibody approach for addressing how viruses like SARS-CoV-2, which causes COVID-19, evolve to evade vaccines and treatments. Details on the results were published October 23 in the journal Cell.

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The John and Daria Barry Foundation will expand clinical and research programs on eye disease

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The Cohen Center for Recovery From Complex Chronic Illnesses will also research new therapies for these conditions

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Mount Sinai Health System today announced that Mount Sinai BioDesign, the medical technology incubator of the Health System, has expanded its reach to become a key, effective partner for the broader MedTech community.

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CEO of the Mount Sinai Health System and Chair of the Emergency Department for Mount Sinai Queens will be honored for their contributions to health policy and diversity, inclusion, and health equity

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Mount Sinai study also shows imaging for early detection and monitoring can improve prediction and prevention of premature death