Studies investigate monthly cycle fluctuations, trial results reducing excess androgens, transcranial magnetic stimulation to treat depression, and liver regeneration
A UT Southwestern Medical Center study of hundreds of underserved women showed that depression and anxiety, in addition to physical factors such as a higher body mass index and previous births, are associated with lingering postpartum urinary incontinence.
Researchers at UT Southwestern Medical Center developed nanoparticles that successfully edited the disease-causing gene in the lungs of a mouse model of cystic fibrosis (CF), swapping a mutated form with a healthy one that persisted in stem cells. Their findings, reported in Science, could offer hope for people with CF and other debilitating genetic lung diseases.
Patients with moderate to severe treatment-resistant depression (TRD) might have better symptom relief from ketamine infusions than from electroconvulsive therapy (ECT), but those with severe TRD could benefit more from ECT early in treatment, an analysis led by a UT Southwestern Medical Center researcher shows. The findings, published in JAMA Network Open, are the first to identify characteristics that distinguish which treatments might benefit TRD patients more.
A weekly dose of semaglutide 2.4 mg significantly reduced the risk of major adverse cardiovascular events (MACEs) in people with overweight or obesity and cardiovascular disease but not diabetes, regardless of blood sugar level, according to a clinical trial including researchers from UT Southwestern Medical Center. The findings, published in Diabetes Care, also show the reduction in MACEs – a combination of heart attacks, stroke, or death from cardiovascular causes – isn’t due to the drug’s effect in lowering blood sugar.
A statistical tool designed to analyze 11 characteristics of postmortem brains reliably diagnosed a common neurodegenerative disease known as essential tremor (ET), a study led by researchers at UT Southwestern Medical Center and Columbia University shows. Their findings, 20 years in the making and published in the Annals of Clinical and Translational Neurology, could eventually help relatives of deceased ET patients know their hereditary risk of getting the disease.
More clinical research is needed to investigate how reducing alcohol consumption in patients with alcohol-related liver disease (ALD) may slow disease progression and improve outcomes, according to an international task force of experts from more than two dozen institutions including UT Southwestern Medical Center.
Boston Celtics 7’2” center Kristaps Porzingis was ruled out of Game 3 against the Dallas Mavericks, his former team, due to a “torn medial retinaculum, allowing dislocation of the posterior tibialis tendon” (PTT), according to a team statement from ESPN. This injury comes on the heels of a string of calf injuries earlier in the season.
Mysterious cells that secrete hormones in the large intestine play a key role in regulating body weight through their relationship with intestinal bacteria, a study led by UT Southwestern Medical Center researchers suggests. Their findings, published in Nature Metabolism, could lead to new treatments for obesity and extreme weight loss.
For nearly two decades, how kidney cancer becomes resistant to rapalog drugs has baffled the scientific community. Now a study by researchers at UT Southwestern Medical Center’s Kidney Cancer Program sheds light.
In a large clinical trial, UT Southwestern Medical Center researchers developed a robust model for testing strategies to prevent health problems in patients with multiple chronic conditions.
Strong family relationships have long been associated with a better sense of well-being and connection. Now a team led by UT Southwestern Medical Center researchers has linked the quality of those relationships with how successfully people – particularly aging African Americans – manage pain.
Exercising at a high level doesn’t affect the progression of calcium buildup in the arteries, even among older athletes such as marathoners who tend to have higher coronary artery calcium (CAC) scores, according to new research from UT Southwestern Medical Center. But a longer duration of exercise is associated with higher CAC.
A new initiative funded by The University of Texas System and the state of Texas seeks to improve care for trauma patients, including both service members and civilians.
Two genes working in tandem play a critical role in shaping the identity and behavior of prostate cancer cells and their response to treatment, UT Southwestern Medical Center researchers report.
A novel speech analysis tool that uses artificial intelligence successfully detected mild cognitive impairment and dementia in a Spanish-speaking population, according to research led by UT Southwestern Medical Center. The study, published in Frontiers in Neurology, provides preliminary support for the algorithm as an early screening tool that may help identify patients at risk of developing dementia.
In 2021, researchers at UT Southwestern Medical Center used artificial intelligence and deep machine learning to analyze 1.7 million raw images of patient-derived tumor samples, pinpointing a key distinction between skin cancer cells with high and low potential to metastasize – a discovery that could ultimately mean the difference between life or death for patients.
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