Each year, nearly 16,000 U.S. children and teens are diagnosed with cancer. But only 4 percent of federal cancer research funding is earmarked to develop new treatments and cures for children battling this heartbreaking disease – an amount that is far below what is actually needed.
UCSF Benioff Children’s Hospital Oakland clinical researchers, in conjunction with other sickle cell centers and scientists at Emmaus Life Sciences, Inc., have demonstrated that therapy with L-Glutamine reduced the frequency of pain episodes in both pediatric and adult patients with sickle cell disease (SCD). The results of the 48-week, phase 3 clinical trial are published in the July 19, 2018, issue of New England Journal of Medicine (NEJM).
A pilot clinical trial by UCSF Benioff Children’s Hospital Oakland Research Institute (CHORI) researchers has found that targeted nutrient therapy can improve lung function in obese individuals with asthma, without requiring weight loss. The study, published in The FASEB Journal, demonstrated that eating two CHORI-Bars daily for eight weeks improved lung function in obese adolescents with a form of asthma that is resistant to usual treatments.
Dave Grohl, frontman of rock band Foo Fighters, joined renowned authors for the ninth annual Notes & Words on Saturday, May 12, at the historic Fox Theater. This one-night-only event raised more than $1.8 million for our Oakland campus.
Interim results of clinical trials by investigators at UCSF Benioff Children’s Hospital Oakland and Ann and Robert H. Lurie Children’s Hospital of Chicago reveal that a majority of the 22 patients in two Phase 1/2 studies followed for two years or longer remained free from transfusions. The results of the trials “Gene Therapy in Patients with Transfusion-Dependentβ-Thalassemia,” are published today in the New England Journal of Medicine (NEJM). The results are from two separate, two-year clinical studies using LentiGlobin® gene therapy to stop or reduce chronic blood transfusions in patients with transfusion-dependent β-thalassemia (TDT).
A new study by UCSF Benioff Children's Hospital Oakland researcher Dr. June Tester examined national data on preschool-aged children from 1999 to 2014 to highlight characteristics of children with the highest degree of obesity and found a strong correlation between the amount of “screen time” these children are exposed to and the likelihood of them being severely obese. The study also found that preschoolers with severe obesity are also more likely to be of an ethnic or racial minority and more likely to be living in poverty.
A study by UCSF Benioff Children’s Hospital Oakland researchers, has found that “park prescriptions” provided by physicians to their low-income patients can help reduce stress and improve physical well-being in patients and their families.
A study by UCSF Benioff's Children’s Hospitals sports medicine researchers finds that among elite NBA athletes, those who participated in multiple sports in high school had fewer injuries and longer careers, on average, than players who played only basketball in their adolescence.
UCSF Benioff's Children’s Hospital Oakland Research Institute (CHORI) researcher Dr. Deborah Dean is the recipient of a new award from the Centers for Disease Control and Prevention (CDC) that will support the development and evaluation of new diagnostics tools that can determine the antibiotics to which a patient’s strain of gonorrhea is susceptible. Dean is among the 25 investigators that the CDC awarded more than $9 million in total to pilot innovative solutions and explore knowledge gaps about antibiotic resistance related to the human microbiome, healthcare settings, and surface water and soil.
One-year-old Elias will never remember all the doctors, nurses, and other health care professionals who took care of him for the first five months of his life, but his parents, Gabriela and Rogelio Ramirez, will never forget them.
Children’s Hospital Oakland Research Institute (CHORI) Senior Scientist Dr. Dan M. Granoff, has been awarded the 2017 Distinguished Medical Alumnus Award from his alma mater, the Johns Hopkins University School of Medicine.
The trauma center at UCSF Benioff Children’s Hospital Oakland has been re-verified as a Level I Pediatric Trauma Center by the American College of Surgeons (ACS). Verification by the ACS is the highest possible ranking for trauma centers and this re-designation recognizes the trauma center's continuing dedication to providing optimal care for injured pediatric patients.
An international US-Danish team of scientists, led by Damini Jawaheer, Ph.D. at the UCSF Benioff Children’s Hospital Oakland Research Institute, has identified a possible link between type I interferons and a natural improvement of rheumatoid arthritis (RA) during pregnancy. These findings could have significant implications in the development of safer therapies for RA. This study entitled, “Pregnancy-induced gene expression changes in vivo among women with rheumatoid arthritis: a pilot study,” was published in Arthritis Research & Therapy.
A new study by researchers from the UCSF Benioff Children’s Hospital Oakland Research Institute (CHORI) shows that a modest 4 milligrams of extra zinc a day in the diet can have a profound, positive impact on cellular health that helps fight infections and diseases. This amount of zinc is equivalent to what biofortified crops like zinc rice and zinc wheat can add to the diet of vulnerable, nutrient deficient populations.
A team of scientists led by Julie Saba, MD, PhD at UCSF Benioff Children’s Hospital Oakland, has unveiled a novel role of thymic dendritic cells, which could result in new strategies to treat conditions such as autoimmune diseases, immune deficiencies, prematurity, infections, cancer, and the loss of immunity after bone marrow transplantation.
Supporting the intersection of children’s health and the outdoors, the REI Foundation is awarding a $200,000 grant to UCSF Benioff Children’s Hospital Oakland’s Center for Nature and Health (CNH). CNH develops clinical programs, conducts original research, and seeks to address health inequities by promoting access to nature as part patients’ care and overall well-being.
A team at the Oakland and San Francisco campuses of UCSF Benioff Children’s Hospitals, UCSF, and UC Berkeley have been awarded $1.2 million by California Initiative to Advance Precision Medicine (CIAPM) to help advance precision medicine in the state.
A team of physicians and laboratory scientists has taken a key step toward a cure for sickle cell disease, using CRISPR-Cas9 gene editing to fix the mutated gene responsible for the disease in stem cells from the blood of affected patients. For the first time, they have corrected the mutation in a proportion of stem cells that is high enough to produce a substantial benefit in sickle cell patients.
A study conducted by UCSF Benioff Children's Hospital Oakland Research Institute (CHORI) scientists shows greatly improved protective antibody responses to a new mutant vaccine antigen for prevention of disease caused by Neisseria meningitidis - also known as meningococcus - that has the potential to improve the current vaccines for meningitis.
David Killilea, PhD, a staff scientist at Children's Hospital Oakland Research Institute (CHORI), co-authored a study into the causes of kidney stones. The study was conducted by the University of California, San Francisco (UCSF), in collaboration with the Buck Institute for Research on Aging in Marin County and Children's Hospital Oakland Research Institute (CHORI). Published in the prestigious scientific journal PLOS ONE, the study revealed that high levels of zinc in the body may contribute to kidney stone formation.
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