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People exposed to alcohol in utero report a greater range and frequency of physical health problems in midlife than those who were not exposed, according to a new study. Prenatal stressors and difficult early life experiences are known to increase the risk of the early onset of disease in adulthood. A theory on the developmental origins of health and disease implies that risky exposures occurring during pregnancy may increase the offspring’s vulnerability to the effects of subsequent adverse influences. Prenatal alcohol exposure (PAE) may be one such exposure. Improved understanding of the long-term effects of PAE could lead to improved clinical care for affected people. Identifying areas of concern may also inform early interventions to reduce the long-term impact of PAE. In the study in Alcohol: Clinical & Experimental Research, investigators considered the possible implications of PAE for a wide range of health problems that typically occur as people grow older.

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Negative emotions may help explain the link between insomnia and dangerous drinking, according to a small study involving veterans with Alcohol Use Disorder (AUD). The findings provide new insight into why insomnia might be linked AUD. Insomnia symptoms are highly prevalent in people with substance use disorders (SUDs). Among veterans with AUD, for example, almost 2 in 3 experience insomnia.

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Adults aged 35 to 60 are drinking at unprecedented rates, with those who binge drank in high school reporting more past 30-day high-risk drinking in midlife. And this link may be especially strong for women, according to a study just published in Alcohol: Clinical and Experimental Research Health. These trends are particularly concerning as health conditions, and biological processes common with aging put adults in midlife at greater health risk from alcohol use.

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Young adults think electronic interventions might help to reduce the negative consequences of alcohol use if tailored to their personal needs and goals. In a qualitative study, young adults reported that such real-time interventions should be customizable, easy to use, and provide digestible amounts of non-judgmental information.

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People with alcohol use disorder (AUD) may not respond typically to images of food (i.e., cues), according to a novel study using brain imaging.

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Young adults who drink heavily reported that a specific intervention that provides personalized feedback on daily drinking would be beneficial for people who want to reduce their drinking and would encourage self-reflection among those who are not yet ready to change their drinking habits. The young adults were participants in a pilot study of a first-of-its-kind technology aimed at reducing heavy drinking in young adults through self-selected goal setting and daily personalized feedback based on self-reported behaviors related to drinking. The study is described in Alcohol: Clinical and Experimental Research.

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People with alcohol use disorder (AUD) who are at risk of advanced liver disease are less likely to be referred for liver evaluation and care if they present primarily with alcohol-related mental health issues or a mental health diagnosis, according to a study of referral practices in Virginia’s largest health system. The findings point to the possibility of widespread missed opportunities for treating three conditions that commonly co-occur: AUD, mental health disorders, and liver disease. Recent years have seen notable increases in the USA in alcohol-related deaths, mental health disorders, and hospital admissions relating to alcohol use and concurrent mental health conditions. AUD is a significant cause of liver disease, and both addiction and co-occurring mental illness can be barriers to successful liver treatment. Integrating AUD treatment, mental health care, and hepatology (liver care) is necessary to improve outcomes, but data suggests this approach is not the norm. For the st

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Drinking alcohol may predict experiencing physical, psychological, or sexual victimization during or shortly after alcohol use, according to a study published in Alcohol: Clinical and Experimental Research.

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Certain concepts have a demonstrated basis for aiding recovery from dangerous alcohol or substance use, according to an analysis of scientific literature since 1990. Self-efficacy (a belief in one's ability to achieve a goal), social support, and managing cravings are among the treatment elements best supported by evidence. Effective treatment for alcohol use disorder (AUD) and other substance use disorders (SUDs) depends on understanding how human behaviors change and incorporating that knowledge into clinical practice. An ongoing research effort continues to investigate varying treatment approaches and how they relate to recovery outcomes, but those findings have not been well synthesized into a useful format. For the new review published in Alcohol: Clinical & Experimental Research, researchers from around the USA reviewed published studies, identified the treatment elements best supported by data, and evaluated their potential as key factors in behavior change. The researchers drew

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Only four percent of people who are screened and report heavy drinking go on to receive specialty treatment for their alcohol use, according to a study published in Alcohol: Clinical and Experimental Research. The study found race, ethnicity, and health risk profile to be associated with differences in the likelihood of receiving specialty treatment. These findings echo previous studies and highlight the need for more tailored approaches to screening and intervention to improve treatment for diverse groups of people with varying levels of alcohol use problems, from heavy drinking to alcohol use disorder.

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Certain regions of the brain show changes during the early stages after quitting drinking that may contribute to increased anxiety and relapse rates in people attempting recovery from alcohol use disorder, according to a study published in Alcohol: Clinical and Experimental Research.

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In a large group of frequent drinkers who used a digital application offering tailored text-based support for reducing their alcohol intake, weekly drink amounts fell by 1/3 over 12 weeks. The study of real-world users shows promise for people who are uncomfortable with their drinking habits but may not meet the criteria for alcohol use disorder (AUD). Although they may be unlikely to aim for abstinence or to seek formal treatment, many are open to moderating their drinking. Digital interventions, such as self-guided online programs and smartphone apps, are easily accessible and engaging. Studies have shown that text-based messaging interventions can result in short- and medium-term reductions in alcohol use. Digital programs that tailor content according to users’ evolving outcomes, similar to clinical care, may be particularly effective. Outcomes data are limited, however. For the study in Alcohol: Clinical & Experimental Research, researchers evaluated an adaptive, tailored digital

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Rats with alcohol exposure in adolescence are less able as adults to adapt their behavior in changing circumstances, according to a study that highlights the possible brain mechanisms involved. The findings may help us better understand ways that alcohol use during the teen years can lead to long-lasting cognitive and behavioral impairments.

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Young adult men who viewed alcohol warning labels experienced a lower activation of the reward circuits in their brains when the warnings were larger and involved pictures, compared to more familiar small-text warnings, in a first-of-its-type study. The findings could inform more effective messaging on alcohol-containing beverages and advertisements. Despite recommendations from the World Health Organization and European Commission that warning labels be included on alcoholic products, few countries have implemented alcohol warning policies comparable to their approach to tobacco. Alcohol warnings are typically small, text-only messages. Research has been equivocal about their impact on drinking and whether incorporating pictures would increase their effectiveness, in part because most studies have relied on participants’ self-reported reactions. Functional magnetic resonance imaging (fMRI) has demonstrated variations in brain activation in response to varying types of tobacco warnings

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Antidepressants may reduce the risk of relapse in people with alcohol use disorder—but only if the antidepressants are effective in reducing their depression symptoms. People whose depression symptoms do not improve with antidepressant treatment may have an increased risk for relapse into problem alcohol use.

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Children who try alcohol may experience mental health and personality effects as they transition to early adolescence. An analysis of alcohol sampling behavior in children ages 9 to 14, published in Alcohol: Clinical and Experimental Research, found that children who had poor response inhibition and increased alcohol sipping behaviors might be more likely to have accelerated changes in personality traits and depression scores over time. The study suggests that even minimal alcohol experimentation in early adolescence may influence later alcohol use as well as personality and mental health issues.

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Researchers agree that alcohol use can produce global and regional tissue volume changes in the brain, and that excessive alcohol use is associated with dementia and cognitive decline. A new study has examined the relationship between Alzheimer disease – the most common type of dementia – and alcohol use disorder (AUD), discovering biomarkers that link the two.

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There is a clear relationship between alcohol and neurodegeneration; for example, an alcohol use disorder correlates with a higher risk of Alzheimer’s disease. It is unclear, however, whether individual differences in brain structure and connectivity are risk factors for, or consequences of, alcohol use. New research exploring this relationship will be shared on Wednesday, 26 June 2024 at the 47th annual scientific meeting of the Research Society on Alcohol (RSA) in Minneapolis, Minnesota.

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Prevention, intervention, and treatment measures have historically been used to address alcohol use and abuse. New research has explored the use of a smartwatch application to bridge the gap between prevention and intervention, tracking a person’s drinking habits and providing real-time personalized prompts while they are drinking to potentially help them moderate their consumption. These results will be shared at the 47th annual scientific meeting of the Research Society on Alcohol (RSA) in Minneapolis, Minnesota.

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People with severe alcohol use disorder tended to have greater difficulty forming new social memories. And, while they had better immediate recall of positive than negative social cues, for longer-term memories, they tended to remember more negative experiences than positive ones.