Top: Illustration of formation of solid implant by phase inversion and drug release via diffusion and implant degradation. Bottom: Modeling predicted a 2 mL and 3 mL injection can sustain plasma concentrations of CAB above levels needed for protection against HIV in humans for 4 and 5 months, respectively.
Credit: Isabella Young, PhD and Ivana Massud, PhD, espectively.
Isabella Young, PhD student in Dr. Rahima Benhabbour's lab (top) and Ivana Massud, PhD, senior research associate at the CDC (bottom), were co-first authors.