Scientists discuss efforts that have spanned more than a decade to discover insights into the complexities of the brain and mind. Recently, the researchers, including (from left) Dan Bang of Aarhus University in Denmark; Ken Kishida of Wake Forest University School of Medicine; Michael Friedlander, executive director of the Fralin Biomedical Research Institute; Peter Dayan, managing director of the Max Planck Institute for Biological Cybernetics in Tübingen, Germany; and Read Montague, director of the Fralin Biomedical Research Institute Center for Human Neuroscience Research, discussed their scientific journey to understand the mechanisms that make us human.