Key Pathway Leading to Neurodegeneration in Early Stages of ALS Identified

Credit: UC San Diego Health Sciences

Pictured are nuclei of induced pluripotent stem cell (iPSC)-derived motor neurons stained for contrast. The nucleus on the left has been treated with DMSO (control) and appears mostly blue. The nucleus on the right has been treated with an SMN inhibitor and is spotted red, indicating that CHMP7 protein has accumulated in the nucleus. Scale bars =10 µm.

« Key Pathway Leading to Neurodegeneration in Early Stages of ALS Identified

Credit: UC San Diego Health Sciences

First author Norah Al-Azzam and corresponding author Gene Yeo.

« Key Pathway Leading to Neurodegeneration in Early Stages of ALS Identified

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