William Kew, Ph.D.

Dr. William Kew is a chemist with the Biomolecular Pathways team. He works on high-resolution mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy analysis of complex mixtures. Kew joined PNNL and EMSL in 2019 as a postdoctoral research associate and transitioned to staff in summer 2020. He graduated in 2018 from the University of Edinburgh with a PhD in chemistry, studying Scotch whisky as a complex mixture by high-resolution MS and NMR techniques.  
Kew’s research includes instrument and method development on the FTICR and Orbitrap mass spectrometry platforms, method development and validation in NMR, data analysis and visualization, and software development. His current projects include the development of the next generation 21 Tesla FTICR mass spectrometer and several other key technology development projects covering complex mixtures, stable isotopes, and imaging mass spectrometry.

Research Interests



Mass Spectrometry 


NMR Spectroscopy  


Complex Mixtures 


Metabolomics 


Instrument Development 




Software Development 



Education



PhD in Chemistry, The University of Edinburgh, 2018 


MS in Chemistry, University of Saint Andrews, 2014 



Publications

2020 
Kew W.R., and J. Hawkes. 2020. "High resolution mass spectrometry strategies for the investigation of dissolved organic matter." In Multidimensional Analytical Techniques in Environmental Research, edited by Regina Duarte, Armando Duarte. PNNL-SA-146397. 
Hawkes J., J. D'Andrilli, J.N. Agar, M. Barrow, S. Berg, N. Catalan, and H. Chen, et al. 2020. "An international laboratory comparison of dissolved organic matter composition by high resolution mass spectrometry: Are we getting the same answer?" Limnology and Oceanography Methods 18, no. 6:235-258. PNNL-SA-147033. doi:10.1002/lom3.10364 
2019 
Afonso C., M. Barrow, A.N. Davies, M. Delsuc, T. Ebbels, F.A. Fernandez-Lima, and C. Gauchotte-Lindsay, et al. 2019. "Data mining and visualisation: general discussion." Faraday Discussions 218. PNNL-SA-147037. doi:10.1039/C9FD90044F 
Afonso C., M. Barrow, N.A. Bell, A.N. Davies, D. Duca, C. Focsa, and C. Gauchotte-Lindsay, et al. 2019. "Dealing with complexity: general discussion." Faraday Discussions 218. PNNL-SA-147036. doi:10.1039/C9FD90055A