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Sobre la base de trabajos anteriores, los investigadores de ACS Infectious Diseases han demostrado un posible tratamiento antibacteriano a partir de una darobactina modificada, un compuesto originario de una bacteria. El equipo informa de pruebas de concepto en animales con infecciones causadas por bacterias, entre ellas, E. coli, conocidas por desarrollar farmacorresistencia.
Building on previous work, researchers in ACS Infectious Diseases have demonstrated a potential antibacterial treatment from a modified darobactin, a compound originally from a bacterium. The team reports proof-of-concept animal trials on infections caused by bacteria, including E. coli, that are known to develop drug resistance.
A la mayoría de la gente no le gusta aplicarse vacunas o inyecciones para recibir tratamientos. Por eso, los investigadores trabajan para crear más medicamentos, como los que se fabrican a partir de ARN mensajero (ARNm), que puedan pulverizarse e inhalarse. Un estudio publicado en la revista Journal of the American Chemical Society informa sobre los avances para hacer posible los medicamentos de ARNm inhalables. Los investigadores indican que la nanopartícula de polímero lipídico, que es estable cuando se nebuliza y libera aerosoles (gotitas líquidas) en los pulmones de ratones de forma satisfactoria, se optimizó para contener el ARNm.
Los rayos X son un componente habitual de las pruebas diagnósticas y el monitoreo industrial, y se utilizan para todo, desde el control de los dientes hasta el escaneo de maletas en el aeropuerto. Sin embargo, los rayos de elevada energía también producen radiación ionizante, que puede ser peligrosa tras exposiciones prolongadas o excesivas. Ahora, investigadores que publican en ACS Central Science han avanzado hacia rayos X más seguros con la creación de un detector altamente sensible y plegable que genera imágenes de buena calidad con dosis más pequeñas de estos rayos.
A study in the Journal of the American Chemical Society reports steps toward making inhalable mRNA medicines a possibility. Researchers outline their improved lipid-polymer nanoparticle for holding mRNA that is stable when nebulized and successfully delivers aerosols (liquid droplets) in mice’s lungs.
Now, researchers publishing in ACS Central Science have taken a step toward safer X-rays by creating a highly sensitive and foldable detector that produces good quality images with smaller dosages of the rays.
Researchers who previously demonstrated a cooling fabric coating now report on additional tests of a treated polyester fabric in ACS Applied Materials & Interfaces. Fabric treated with the team’s chalk-based coating kept the air underneath up to 6 degrees Fahrenheit cooler in warmer urban environments.
En un estudio publicado en la revista ACS Sensors, investigadores informan del desarrollo de sensores ultrasensibles a nanoescala que, en pruebas a pequeña escala, distinguen un cambio clave en la química del aliento de personas con cáncer de pulmón.
Exhaled breath contains chemical clues to what’s going on inside the body, including diseases like lung cancer. And devising ways to sense these compounds could help doctors provide early diagnoses — and improve patients’ prospects. In a study in ACS Sensors, researchers report developing ultrasensitive, nanoscale sensors that in small-scale tests distinguished a key change in the chemistry of the breath of people with lung cancer. November is Lung Cancer Awareness Month.
Now, researchers reporting in ACS Sustainable Chemistry & Engineering have used computer modeling to study the feasibility and challenges of hydrogen-powered aviation.
Los investigadores que publicaron un informe en la revista Environmental Science & Technology Letters de ACS analizaron la posibilidad de que estos productos de supresión fueran la fuente de los elevados niveles de metales que a veces se encuentran en los cauces tras apagar los incendios forestales.
Researchers reporting in ACS’ Environmental Science & Technology Letters explored whether wildfire suppressants could be a source of elevated metal levels sometimes found in waterways after wildfires are extinguished. Several products they investigated contained high levels of at least one metal.
Researchers publishing in ACS’ Journal of Agricultural and Food Chemistry have created a prototype cultured pork using a new material: kafirin proteins isolated from red sorghum grain.
Motivated by a new EPA standard for fine particulate matter, a type of air pollution, researchers in Environmental Science & Technology Letters have developed a computer model that reveals an urgent need to fix gaps in the current monitoring network.
On behalf of the American Chemical Society (ACS), President Mary K. Carroll congratulates today’s winners of the Nobel Prize in Chemistry: David Baker, of the University of Washington; Demis Hassabis, of Google DeepMind; and John M. Jumper, of Google DeepMind.
It’s important to eat your veggies, but some essential vitamins and nutrients can only be found in animals, including certain amino acids and peptides. But, in a proof-of-concept study published in ACS’ Journal of Agricultural and Food Chemistry, researchers developed a method to produce creatine, carnosine and taurine — all animal-based nutrients and common workout supplements — right inside a plant. The system allows for different synthetic modules to be easily stacked together to boost production.
American Chemical Society (ACS) President Mary K. Caroll will issue a statement on the 2024 Nobel Prize in Chemistry after the official announcement is made from Stockholm on Wednesday, Oct. 9. Caroll will also be available for Zoom interviews.
Scientists reporting in ACS Nano have made their own version of fake spider silk, but this one consists of proteins and heals wounds instead of haunting hallways. The artificial silk is strong enough to be woven into bandages that helped treat joint injuries and skin lesions in mice.
Researchers reporting in ACS Energy Letters have designed a lithium-sulfur (Li-S) battery that features an improved iron sulfide cathode. One prototype remains highly stable over 300 charge-discharge cycles, and another provides power even after being folded or cut.
Researchers in ACS Central Science report a sugar-like polymer that traps heavy metals within insoluble clumps for easy removal. In proof-of-concept tests, the polymer removed ionic cadmium and lead from river water spiked with these persistent contaminants.
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