- Innovation to treat injured soldiers on the battlefield
- The Army teams up with NHS Blood and Transplant
- £4.9 million to support clinical trials in the UK
Newswise — BOSTON, June 14, 2023 /PRNewswire/ -- An innovative project to rapidly deliver blood and plasma to injured soldiers is set to save lives in warzones. The UK Ministry of Defence's Blood Far Forward programme aims to deliver blood and plasma within 30 minutes of injury to soldiers in active warzones.
Dried plasma – which helps the blood to clot – will decrease the Army's reliance on frozen plasma which has to be thawed, taking longer to administer, and could be used by NHS Air Ambulances in the future.
In the warzone most deaths occur within 60 minutes due to catastrophic injury, head injury or major haemorrhage. Early provision of plasma with red cells dramatically reduces mortality from major haemorrhage.
Frozen plasma currently takes an average of 20 minutes to thaw and transporting it poses major logistical challenges, including requiring a freezer and specialist equipment.
In contrast, dried plasma can be stored at room temperature and can be used by the medic when needed.
The Army has now funded NHS Blood and Transplant to find a way to manufacture dried plasma for use on military operations.
At present, the Army sources dried plasma from NATO partners, which subject to significant worldwide demand. Sourcing it from the UK will ensure the Army has adequate supply that is not reliant on other countries.
The project will also enable single units of plasma to be produced without the need of complex facilities and placed in more convenient, plastic bags.
Technological resources for the project will be provided by Velico Medical, who have been contracted by NHSBT to work in collaboration with NHS scientists, including the process of gaining regulatory approval.
UK Minister for Defence People, Veterans and Service Families, Dr Andrew Murrison said:
"We're always striving to improve our ability to treat trauma in the field, and catastrophic injuries that require acute medical attention in adverse environments, including the battlefield, are some of the most challenging.
"Treating people quickly and near to the point of injury is so often critical. That's why spray dried plasma is such an important step forward."
UK Health Minister Neil O'Brien said:
"This project has the potential to save soldiers' lives by treating significant blood loss with plasma.
"We are continuing our history of health innovation on the battlefield and investing in cutting-edge treatments by delivering plasma made in the UK to the front line.
"We work best when we're working together and this project is the perfect example of the government, NHS Blood and Transplant, the Army and medical technologists collaborating to deliver transformative care to people when they need it."
Major General Tim Hodgetts, Surgeon General and Master General of the Army Medical Services, said:
"The Army's leadership in developing a sovereign capability for dried plasma will save the lives of injured Service Personnel on operations, whilst securing our own national supply chain for what is a critical product in high international demand."
Rebecca Cardigan, Head of NHS Blood and Transplant's Component Development Laboratory, said:
"Plasma saves lives every day, by treating massive blood loss. We're now researching and developing a world class dried plasma product which will not only save the lives of the Army's battlefield casualties but could one day be used in civilian care where there are also logistical challenges, such as by Air Ambulance crews."
Richard Meehan, President and CEO of Velico, said:
"Spray-dried plasma is not only highly innovative, but it will change the course of transfusion medicine. We are excited and looking forward to work with our UK champions, in bringing our technology one step closer to changing lives in real-time."
The cost of the project is £4.9 million and will involve clinical trials in the UK. It is expected the resulting product will also benefit the NHS.
Notes to Editors
- The UK has a track record of innovation in the field of blood supplies to the battlefield. During World War Two, 300,000 units of dried plasma were manufactured in Cambridge and supplied most of the allies.
- The Blood Far Forward programme is part of the work the Army's Futures Directorate is doing to improve battlefield logistics. This includes the Army Warfighting Experiment and the Human Machine Teaming project which is bringing robotics and autonomous systems into the Army by 2025.
- The project will be delivered over the course of three years.
- NHS Blood and Transplant is a joint England and Wales Special Health Authority which provides the blood, plasma and platelet donation service for England and the organ donation service for the UK.
- Velico Medical, Inc. is a private US medical technology company, committed to the mission of eliminating preventable death from bleeding. Headquartered in Beverly, Massachusetts, USA. Velico personnel have substantial expertise and experience in transfusion medicine and medical device development. In support of its mission, Velico is developing partnerships with civilian, government and military blood center leadership, trauma surgeons, emergency medical physicians, military medics and first responders worldwide. Velico's development program has been funded in whole or in part with Federal funds from the US Department of Health and Human Services; Administration for Strategic Preparedness and Response; Biomedical Advanced Research and Development Authority, under contract number 75A50121C00059.
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