Credit: Huebsch lab, Washington University in St. Louis
This image shows the microtissues from Nate Huebsch’s lab that are stained for cell nuclei (blue), sarcomeric alpha-actinic (red) and Myosin Binding Protein C (MYBPC3; green). Mutations in MYBPC3 cause hypertrophic cardiomyopathy. These sarcomere structures are disrupted by chemical blebbistatin.