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UCLA Scientists Propose Benchmark to Better Replicate Natural Stem Cell Development in the Laboratory Environment

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UCLA researchers have developed a benchmark to assess how well stem cell culture conditions in the lab resemble counterparts in the developing embryo

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For Brain Hemorrhage, Risk of Death Is Lower at High-Volume Hospitals

For patients with a severe type of stroke called subarachnoid hemorrhage (SAH), treatment at a hospital that treats a high volume of SAH cases is associated with a lower risk of death, reports a study in the November issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

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New Insight on Why People with Down Syndrome Invariably Develop Alzheimer’s Disease

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Researchers discover the cell events in the brains of individuals with Down syndrome that lead to the amyloid pathology observed in the brains of patients with Alzheimer’s disease. The findings support a novel approach to treating and preventing both diseases.

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Cornell Chemists Show ALS Is a Protein Aggregation Disease

Using a technique that illuminates subtle changes in individual proteins, chemistry researchers at Cornell University have uncovered new insight into the underlying causes of Amyotrophic Lateral Sclerosis (ALS).

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Reminiscing Can Help Boost Mental Performance

New research led by Cornell University neuroscientist Nathan Spreng shows for the first time that engaging brain areas linked to so-called “off-task” mental activities (such as mind-wandering and reminiscing) can actually boost performance on some challenging mental tasks. The results advance our understanding of how externally and internally focused neural networks interact to facilitate complex thought, the authors say.

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EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 26-Oct-2014 2:00 PM EDT

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Can Bariatric Surgery Lead to Severe Headache?

Bariatric surgery may be a risk factor for a condition that causes severe headaches, according to a study published in the October 22, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology.

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A New Window of Opportunity to Prevent Cardiovascular and Cerebrovascular Diseases Identified by Mount Sinai Researchers

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Future prevention and treatment strategies for vascular diseases may lie in the evaluation of early brain imaging tests long before heart attacks or strokes occur, according to a systematic review conducted by a team of cardiologists, neuroscientists, and psychiatrists from Icahn School of Medicine at Mount Sinai and published in the October issue of JACC Cardiovascular Imaging.

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EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 29-Oct-2014 4:00 PM EDT

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Human Skin Cells Reprogrammed Directly Into Brain Cells

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Scientists have described a way to convert human skin cells directly into a specific type of brain cell affected by Huntington’s disease, an ultimately fatal neurodegenerative disorder. Unlike other techniques that turn one cell type into another, this new process does not pass through a stem cell phase, avoiding the production of multiple cell types, report researchers at Washington University School of Medicine in St. Louis.

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