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One Common Genetic Variant and the Bacteria Inside Of Us Help Dictate Inflammation, Antitumor Activity, and Outcome in Cancer Patients

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New findings show how an inactivating polymorphism in the TLR5 Gene that occurs in more than one out of 15 people, plays important role in progression of luminal breast cancer and ovarian cancer

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A reporter's PressPass is required to access this story until the embargo expires on 22-Dec-2014 3:00 PM EST

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EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 22-Dec-2014 3:00 PM EST

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RNA Measurements May Yield Less Insight About Gene Expression Than Assumed

The majority of RNA expression differences between individuals have no connection to the abundance of a corresponding protein, report scientists from the University of Chicago in Science. The results point to a yet-unidentified gene regulatory mechanism.

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Machine Learning Reveals Unexpected Genetic Roots of Cancers, Autism and Other Disorders

University of Toronto researchers from Engineering, Biology and Medicine teach computers to ‘read the human genome’ and rate likelihood of mutations causing disease, opening vast new possibilities for medicine

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23andMe Study Sketches Genetic Portrait of the United States

23andMe announces the first large-scale nationwide study pinpointing differences in genetic ancestry of individuals from across the United States.

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"Master Regulator" Gene — Long Tied to Autism Disorders — Can Stimulate Other Genes Involved in Early Brain Development

Chemical modifications to DNA’s packaging — known as epigenetic changes — can activate or repress genes involved in autism spectrum disorders (ASDs) and early brain development, according to a new study to be published in the journal Nature on Dec. 18.

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Genetic Variations Found to be Associated with Traits Underlying Type 2 Diabetes in Mexican-Americans

While people of Mexican ancestry are nearly twice as likely to develop Type 2 diabetes as people of European heritage, the majority of research in this area has focused on those of European origin.

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‘Microlesions’ in Epilepsy Discovered by Novel Technique

Using an innovative technique combining genetic analysis and mathematical modeling with some basic sleuthing, researchers have identified previously undescribed microlesions in brain tissue from epileptic patients. The millimeter-sized abnormalities may explain why areas of the brain that appear normal can produce severe seizures in many children and adults with epilepsy.

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A Novel Tool to Study Life-Threatening Arrhythmias: A Genetically Engineered Pig

Researchers from NYU Langone Medical Center have developed the first animal model with inherited cardiac arrhythmia -- an advance that could lead to better understanding of the biological mechanisms of normal heart conduction and rhythm.

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