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Mount Sinai Researchers Identify Genetic Alterations in Shared Biological Pathways as Major Risk Factor for Autism Spectrum Disorder

A substantial proportion of risk for developing autism spectrum disorders (ASD), resides in genes that are part of specific, interconnected biological pathways, according to researchers from the Icahn School of Medicine at Mount Sinai, who conducted a broad study of almost 2,500 families in the United States and throughout the world.

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You May Have Billions and Billions of Good Reasons for Being Unfit

Although our chromosomes are relatively stable within our lifetimes, the genetic material found in our mitochondria is highly variable across individuals and may impact upon human health, say researchers at the University of Montreal and its affiliated CHU Sainte-Justine Hospital.

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A reporter's PressPass is required to access this story until the embargo expires on 4/28/2014 11:00 AM EDT

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Surprising New Insights Into PTEN Tumor Suppressor Gene

Ever since it was first identified more than 15 years ago, the PTEN gene has been known to play a key role in preventing the onset and progression of numerous cancers. New research from Beth Israel Deaconess Medical Center helps explain how.

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Researchers Discover New Genetic Brain Disorder in Humans

A newly identified genetic disorder associated with degeneration of the central and peripheral nervous systems in humans, along with the genetic cause, is reported in the April 24, 2014 issue of Cell.

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Aging and Genes: Meet and Question Researchers Live on Newswise

Newswise is offering reporters a behind-the-scenes look at the state of the research and the impact it might have on global public health by interacting with two leading scientists in the field and an author who has investigated the research for over a decade. With all the elements of a great story, the search for healthful human longevity sheds light on discoveries that could fundamentally reshape human life.

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A reporter's PressPass is required to access this story until the embargo expires on 4/28/2014 3:15 PM EDT

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With “The Drama of DNA,” Bioethicists Use Theatrical Narratives To Bridge the Gap Between Society and Science

A new book from bioethicists at Johns Hopkins and Columbia Universities uses dramatic narratives as an accessible gateway to the complex ethical issues of integrating genomics and healthcare.

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From Liability to Viability: Genes on the Y Chromosome Prove Essential for Male Survival

The human Y chromosome has over the course of millions of years of evolution has preserved a small set of genes that has ensured not only its own survival but also the survival of men. Moreover, the vast majority of these tenacious genes appear to have little if any role in sex determination or sperm production. Taken together, these remarkable findings suggest that because these Y-linked genes are active across the body, they may actually be contributing to differences in disease susceptibility and severity observed between men and women.

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Fast Way to Measure DNA Repair

Test analyzing cells’ ability to fix different kinds of broken DNA could help doctors predict cancer risk.

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