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New Study Finds Heart Attacks Do Not Have as Strong of a Genetic Link As Previously Suspected

Heart attacks are not as connected to family history and genetics as may have been previously believed, according to a new study by researchers at the Intermountain Medical Center Heart Institute in Salt Lake City.

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EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 23-Oct-2014 12:00 PM EDT

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NUS-Led Research Team Develops Novel Solutions to Fight the Obesity Gene

A research team led by scientists from the National University of Singapore (NUS) has identified several potent inhibitors that selectively target FTO, the common fat mass and obesity-associated gene.

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New Test Scans All Genes Simultaneously to Identify Single Mutation Causing Child’s Rare Genetic Disease

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A JAMA study found that sequencing the DNA of children with mystery genetic disorders produced a definitive diagnosis in 40 percent of UCLA’s most complex cases--a quantum leap from the field’s 5-percent success rate 20 years ago.

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Genetic Defect Links Rare Infections to Autoimmune Diseases

A team led by researchers at The Rockefeller University and the Icahn School of Medicine at Mount Sinai has explained the function of key immune protein and solved an international medical mystery, according to a letter published this week in the journal Nature.

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New Guideline in Genetic Testing for Certain Types of Muscular Dystrophy

Rochester, Minn. – The American Academy of Neurology (AAN) and the American Association of Neuromuscular & Electrodiagnostic Medicine (AANEM) offer a new guideline on how to determine what genetic tests may best diagnose a person’s subtype of limb-girdle or distal muscular dystrophy. The guideline is published in the October 14, 2014, print issue of Neurology®, the medical journal of the AAN.

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Key Moment Mapped in Assembly of DNA-Splitting Molecular Machine

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Scientists reveal crucial steps and surprising structures in the genesis of the enzyme that divides the DNA double helix during cell replication

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Two-Faced Gene: SIRT6 Prevents Some Cancers but Promotes Sun-Induced Skin Cancer

SIRT6—a protein that inhibits the growth of liver and colon cancers—can promote the development of skin cancers by turning on an enzyme that increases inflammation, proliferation and survival of sun-damaged skin cells. This suggests that SIRT6 could provide a useful target for cancer prevention.

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For One Family, Zebrafish Help Provide Genetic Answers

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Research in zebrafish has helped identify the cause of an unknown genetic disorder affecting a boy and two of his uncles, scientists report in the journal GENETICS. The researchers tracked down a mutation carried only by the affected males and their mothers, within a gene called RPL10 . When the equivalent gene was suppressed in zebrafish, the animals developed smaller heads, which is one of the major symptoms of the human disease.

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Protein Found in Insect Blood That Helps Power Pests' Immune Responses

By studying a protein called beta-1,3-glucan recognition protein in the blood of a caterpillar, researchers have found a genetic mechanism that may help trigger an insect's immune system into killing pathogens in the insect's blood.

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