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Science

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A Quark Like No Other, Biophysics Plays Key Role in Immune System Signaling and Response, ALMA Reveals Sun in New Light, and MORE in the Physics News Source Sponsored by AIP

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Medicine

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Social Environment, Health, mice

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 25-Jan-2017 2:00 PM EST

Science

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hypomorphic mutants, Genetic Engineering, poly adenylation

New Genetic Engineering Technique Could Help Design, Study Biological Systems

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A new technique helps biologists tinker with genes, whether the goal is to turn cells into tiny factories churning out medicines or to study their effects on human health. The technique allows scientists to precisely regulate how much protein is produced from a particular gene.

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Largest Populus SNP Dataset Holds Promise for Biofuels, X-Ray Imaging at Argonne Captures Material Defect Process, Flexible Ferroelectrics Bring Two Material Worlds Together, and More in the DOE Science News Source

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Medicine

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St. Jude Children's Research Hospital, AMKL, pediatric leukemia, next-generation sequencing, Acute Megakaryoblastic Leukemia, genetic alteration, therapy guidelines

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 23-Jan-2017 11:00 AM EST

Medicine

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Nyu Langone, Agnel Sfeir, Mitochondria, Genetics, common deletion, strand displacement, Pearson syndrome, Kearns-Sayre, ophthalmopl

Roots of Related Genetic Diseases Found in Cell Powerhouses

Scientists at NYU Langone Medical Center have discovered the mechanisms behind a genetic change known to cause a set of related diseases.

Medicine

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Research, Cancer, Pancreatic Cancer, Stomach Cancer, Colon Cancer

‘Collateral’ Lethality May Offer New Therapeutic Approach for Cancers of the Pancreas, Stomach and Colon

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Cancer cells often delete genes that normally suppress tumor formation. These deletions also may extend to neighboring genes, an event known as “collateral lethality,” which may create new options for development of therapies for several cancers.

Medicine

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Parents Struggle with When to Keep Kids Home Sick From School; Experts on Peanut Allergies Weigh In on New Guidelines; A Better Way to Test for Jaundice, and More in the Children's Health News Source

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Science

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Fossils, Trilobites, cruziana , palaeozoic

Fossils Found Reveal Unseen ‘Footprint’ Maker

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Fossils found in Morocco from the long-extinct group of sea creatures called trilobites, including rarely seen soft-body parts, may be previously unseen animals that left distinctive fossil ‘footprints’ around the ancient supercontinent Gondwana.

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Cancer, Melanoma, PD-1 blockade, Skin Cancer, Drug Resistance

Ludwig Study Reveals Why Cancer Cells Spread Within the Body

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Findings uncover an ancient mechanism that makes cancer cells invasive, explains melanoma’s resistance to therapy and opens the door to development of novel cancer therapies

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Best Treatment Option Written in Cancer's Genetic Script

Acute myeloid leukaemia study finds personalised therapy is possible.

Medicine

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Andrew Feinberg, Pancreatic Cancer, Epigenetic, Metastases, Tumor

Potentially Reversible Changes in Gene Control 'Prime' Pancreatic Cancer Cells to Spread

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A multicenter team of researchers reports that a full genomic analysis of tumor samples from a small number of people who died of pancreatic cancer suggests that chemical changes to DNA that do not affect the DNA sequence itself yet control how it operates confer survival advantages on subsets of pancreatic cancer cells.

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Genomics, Environment, Antarctic, Ocean, Diatoms, Evolution, Ecosystem, Genetics, Phytoplankton, Adaptation, Eukaryotes, eukaryotic biology, Population Genetics

Tracking Antarctic Adaptations in Diatoms

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An international team of researchers conducted a comparative genomic analysis to gain insights into the genome structure and evolution of the diatom Fragillariopsis cylindrus, as well as its role in the Southern Ocean.

Medicine

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"Mysterious" Non-Protein-Coding RNAs Play Important Roles in Gene Expression, NCI-Designated Cancer Centers Endorse Updated HPV Vaccination Recommendations, and More in the Cancer News Source

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Scientists Find New Genetic Influences on Fat Distribution

Texas Biomed scientists part of consortium finding new areas of genetic influence for body fat distribution in multiethnic study

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Biology, Genetics, Evolution, Fruit Flies

Scientists Engineer Animals with Ancient Genes to Test Causes of Evolution

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Scientists at the University of Chicago have created the first genetically modified animals containing reconstructed ancient genes, which they used to test the evolutionary effects of genetic changes that happened in the deep past on the animals’ biology and fitness.

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Common Epilepsies Share Genetic Overlap with Rare Types

Researchers at Columbia University Medical Center and NewYork-Presbyterian showed that several genes implicated in rare forms of pediatric epilepsy also contribute to common forms of the disorder.

Science

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Genetics, Genome, Human Genome Sequence, Precision Medicine, Disease Risk, Genetic Predisposition, UTHealth , boerwinkle

UTHealth Study Outlines Framework for Identifying Disease Risk in Genome Sequence

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– Imagine a day when you visit the doctor’s office for your annual physical. Your physician orders routine tests – cholesterol, glucose and blood count – but they also order a sequence of your genome, all 3 billion letters of it. Routine genomic testing is not far away, according to researchers at The University of Texas Health Science Center at Houston (UTHealth).

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“Mysterious” Non-Protein-Coding RNAs Play Important Roles in Gene Expression

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Enhancers boost the rate of gene expression from nearby protein-coding genes so a cell can pump out more of a needed protein molecule. A mysterious subset of non-coding RNAs - enhancer RNAs (eRNAs) are transcribed from enhancer sequences. Shedding new light on these elusive eRNAs, researchers showed that CBP, an enzyme that activates transcription from enhancers, binds directly to eRNAs to control patterns of gene expression by acetylation.

Medicine

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Molecular Biology, Genetics, DNA, PCR, Left-handed DNA, Infectious Disease, Diagnoses Disease

DNA Duplicator Small Enough to Hold in Your Hand

Left-handed DNA is the mirror image of the DNA found in all living things. It has the same physical properties as regular, right-handed DNA but it does not participate in most biological reactions. As a result, when fluorescently tagged L-DNA is added to a PCR sample, it behaves in an identical way to the regular DNA and provides a fluorescent light signal that reports information about the molecular reactions taking place and can be used to control them.







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