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Medicine

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MERS, Middle East Respiratory Syndrome, Rabies, Virus, Vaccine, genes, Camel, bats, DNA, Protein

Researchers Combine MERS and Rabies Viruses to Create Innovative 2-for-1 Vaccine

In a new study, researchers have modified a rabies virus, so that it has a protein from the MERS virus; this altered virus works as a 2-for-1 vaccine that protects mice against both Middle East Respiratory Syndrome (MERS) and rabies.

Medicine

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Breast Cancer, Hereditary, Genetic Testing

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 7-Dec-2016 4:15 PM EST

Medicine

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Idiopathic Pulmonary Fibrosis (Ipf), Surfactant Research, Journal of Clinical Investigation Insight, JCI Insight, Cincinnati Children's Hospital Medical Center, Pediatric, news, single-cell analysis, single cell genomics

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 8-Dec-2016 9:00 AM EST

Medicine

Science

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alcohol use disorders, personality traits, Resilience, Genetics, Environment, risk, Influences

Resilience: A Small, Quiet Word with Huge Alcohol Use Disorder Implications

Certain personality traits – such as disinhibition (a lack of restraint) and impulsivity – increase the chances of developing alcohol use disorders (AUDs).

Science

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Bethlehem Star May Not Be a Star After All, The "Eye" of Majoranas, Cloud in a Box, and MORE in the Physics News Source Sponsored by AIP

Click here to go directly to the Physics News Source Sponsored by AIP.

Medicine

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DNA, endogenous retrovirus, Human Genome, provirus

BGSU Researcher: More Ancient Viruses Lurk in Our DNA Than We Thought

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In our recent study, we identified 19 “new” pieces of DNA — left by retroviruses that first infected our ancestors’ germlines hundreds of thousands of years ago –lurking between our own genes.

Science

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Biology, DNA, genes, Neuromuscular, neurodegernative, Huntington's Disease, Genetics

Tufts Researchers Uncover Possible Source of Genetic Error Behind a Dozen Debilitating Diseases

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Researchers have discovered a possible explanation for a genetic error that causes over a dozen neuromuscular and neurodegenerative disorders.

Medicine

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Cells, Self Repair, Cells Self Repair, Geneticist, 2017 Breakthrough Prize, Harvard Medical School, Stephen J. Elledge , DNA, Biology

Geneticist Stephen J. Elledge Wins Breakthrough Prize

Stephen Elledge, the Gregor Mendel Professor of Genetics and of Medicine at Brigham and Women’s Hospital and Harvard Medical School, has been named a 2017 recipient of the Breakthrough Prize, which recognizes paradigm-shifting discoveries in the life sciences, physics and mathematics.  Elledge is being honored for his wide-ranging contributions across multiple fields in biology.

Medicine

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Hemophilia, Gene Therapy, Hemophilia B, Clinical Trial, clotting factor IX, Children's Hospital Of Philadelphia

After One Dose of Gene Therapy, Hemophilia B Patients Maintain Near-Normal Levels of Clotting Factor

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Researchers are reporting the highest and most sustained levels to date of an essential blood-clotting factor IX in patients with the inherited bleeding disorder hemophilia B. After receiving a single dose of an experimental gene therapy in a clinical trial, patients with hemophilia produced near-normal levels of clotting factor IX, allowing them to stop clotting factor infusions and to pursue normal activities of daily life without disabling bleeding episodes.

Science

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Leukemia, t-MNs, clonal hematopoiesis, Genomic Medicine, MD Anderson Cancer Center

Biomarker May Predict Which Formerly Treated Cancer Patients Will Develop Highly Fatal Form of Leukemia

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Patients successfully treated for breast, colon and other cancers can go on to develop an often-fatal form of leukemia, sometimes years after completion of treatment, due to a genetic mutation leading to secondary malignancies known as therapy-related myeloid neoplasms (t-MNs).

Science

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Where the Rains Come From, Glowing Crystals Can Detect Contaminated Drinking Water, 'Polarons' and More in the DOE Science News Source

Click here to go directly to the DOE Science News Source

Medicine

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genetics and autism

Landmark Autism Genetic Study Seeking Participants

Families with a loved one on the autism spectrum now have an opportunity to participate in a landmark study researching the genetics of autism. The national study is the largest autism research project to date.

Medicine

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Cancer, Fausto J. Rodriguez, genes, Tumors, Telomerase

Johns Hopkins Researchers Uncover More Genetic Links to Brain Cancer Cell Growth

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Two recently discovered genetic differences between brain cancer cells and normal tissue cells — an altered gene and a snippet of noncoding genetic material — could offer clues to tumor behavior and potential new targets for therapy, Johns Hopkins scientists report.

Medicine

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Penn Scientists Use CRISPR for First Time to Correct Clotting in Newborn and Adult Mice

CRISPR/Cas9, a powerful genome editing tool, is showing promise for efficient correction of disease-causing mutations. For the first time, researchers have developed a dual gene therapy approach to deliver key components of a CRISPR/Cas9-mediated gene targeting system to mice to treat hemophilia B.

Medicine

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Cancer Risks in Blacks: 'A Complex, Entangled Web', Many Primary Care Doctors Are Reluctant to Talk About Medical Errors, Can Microbiome Influence Treatment Response, and More in the Cancer News Source

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Science

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Diabetes, Insulin, Platypus, Echidna, Monotreme, GLP-1, glucagon-like peptide 1, Blood Sugar, diabetes treatment, Genetics, Evolution, Venom

Platypus Venom Could Hold Key to Diabetes Treatment

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Australian researchers have discovered remarkable evolutionary changes to insulin regulation in two of the nation's most iconic native animal species – the platypus and the echidna – which could pave the way for new treatments for type 2 diabetes in humans.

Medicine

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β-Klotho gene , DNA, social drinking, Alchohol, Ut Southwestern, Gene

UT Southwestern Researchers’ International Study Zeros in on Gene That Limits Desire to Drink Alcohol

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In the largest study of its kind, UT Southwestern Medical Center researchers and colleagues in Europe identified a gene variant that suppresses the desire to drink alcohol.

Science

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Microbiome

Genes, Early Environment Sculpt the Gut Microbiome

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A new study finds that environment and genetics determine relative abundance of specific microbes in the gut. The findings represent an attempt to untangle the forces that shape the gut microbiome, which plays an important role in keeping us healthy.

Medicine

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Biomedicine, Gastroenterology, enteritis, Autoimmune Disease, Melanoma, chronic inflammation, Diarrhea

Successfully Treating Genetically Determined Autoimmune Enteritis

Using targeted immunotherapy, doctors have succeeded in curing a type of autoimmune enteritis caused by a recently discovered genetic mutation. This report comes from researchers at the Department of Biomedicine of the University of Basel and University Hospital Basel. Their results raise new possibilities for the management of diarrhea, which is often a side effect of melanoma treatment.

Medicine

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Parkinson's Disease, Gene Mutation

Gene Mutation Linked to Early Onset of Parkinson’s Disease in Caucasians

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A defect in a gene that produces dopamine in the brain appears to accelerate the onset of Parkinson’s disease, according to new research from Iowa State University. The effect is particularly dramatic for young-to-middle-age adults.







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