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Genomic Study Tracks African-American Dispersal in the Great Migration

Data from cohort studies helps reconstruct African-American heritage from before Civil War.

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Researchers Identify Genetic Subtypes Linked to Increased Risk of Ovarian Cancer

Researchers in the Center for Immunotherapy at Roswell Park Cancer Institute (RPCI) have evaluated the human leukocyte antigen (HLA), a group of genes that help regulate the body’s immune system, for underlying differences in ovarian cancer patients’ response to therapy. The scientists report that women with certain types of HLA may have an increased risk of ovarian cancer and may also respond better to immunotherapy. The research was recently published online ahead of print in the journal Gynecologic Oncology.

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Genes That Increase Children's Risk of Blood Infection Identified

African study finds genes that double the chance of developing bacteraemia when infected with the Streptococcus pneumoniae bacteria.

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Top-Down Design Brings New DNA Structures to Life

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Among the valuable holdings in London's Wellcome Library is a rough pencil sketch made in 1953 by Francis Crick. The drawing is one of the first to show the double-helix structure of DNA--Nature's blueprint for the design of sea snails, human beings, and every other living form on earth.

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Women May Be Able to Reduce Breast Cancer Risk Predicted by Their Genes

Women with a high risk of developing breast cancer based on family history and genetic risk can still reduce the chance they will develop the disease in their lifetimes by following a healthy lifestyle, new research led by the Johns Hopkins Bloomberg School of Public Health suggests.

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EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 1-Jun-2016 12:00 AM EDT

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Researchers Identify Immune Genes Tied to Common, Deadly Brain Cancer

Researchers have identified a group of immune system genes that may play a role in how long people can live after developing a common type of brain cancer called glioblastoma multiforme, a tumor of the glial cells in the brain. The research is published in the May 25, 2016, online issue of Neurology®, the medical journal of the American Academy of Neurology.

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Fixing Cystic Fibrosis: In Vitro Studies Show Therapeutically Robust Correction of the Most Common CF Gene Mutation

In experiments with isolated cystic fibrosis lung cells, University of Alabama at Birmingham researchers and colleagues from two other institutions have partially restored the lost function of those cells to therapeutic levels.

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EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 30-May-2016 11:00 AM EDT

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Researchers Identify Genes Linked to the Effects of Mood and Stress on Longevity

The visible impacts of depression and stress that can be seen in a person's face -- and contribute to shorter lives -- can also be found in alterations in genetic activity, according to newly published research from the Indiana University School of Medicine and the Scripps Research Institute.

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MD Anderson Study Uncovers Early Genetic Changes in Premalignant Colorectal Tissue

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Researchers at The University of Texas MD Anderson Cancer Center have discovered mutations that may fuel early cancer growth in precancerous colorectal tissue from high-risk patients.

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The Trial, Error of Viral Evolution: The Difference Between Fading Out, Pandemic

In a review article, researchers from Virginia Tech, Yale University, and the National Institutes of Health study viral evolution with the aim of finding knowledge that might help prevent disease.

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Drop in Childhood Obesity Cannot Be Explained by Health Behaviors, The Latest in Heart Defect Prediction Tech, Eating After 8pm Not Linked to Childhood Obesity, and more Children's Health News

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Temperature Influences Gene Expression, Life Cycle in Vibrio cholerae

Vibrio cholerae infects roughly four million people annually, worldwide, causing severe diarrheal disease, and killing an estimated 140,000 people. Its success as a pathogen belies the challenges this bacterium faces. The waters this bacterium inhabits when it's not infecting H. sapiens can be 40 degrees Fahrenheit cooler than our normal body temperature. Now a team of investigators from the University of California, Santa Cruz provides new insights into how different temperatures in the bacterium's environment control expression of genes required for life at those temperatures. The research is published ahead of print May 20, 2016 in Applied and Environmental Microbiology, a journal of the American Society for Microbiology.

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Genetic Engineering Report Findings Supported by Crop, Agronomy Societies

The recent NAS report on genetically engineered crops aligns with statements from Agronomy and Crop Societies: Scientific research overwhelmingly shows GE crops are safe and pose no significant health or environmental risks.

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Appeal of 'Genetic Puzzles' Leads to National Medal of Science for UW's Mary-Claire King

In a White House ceremony May 19, President Barack Obama presented the National Medal of Science to Mary-Claire King, University of Washington professor of genome sciences and medicine. The award, the nation's highest recognition for scientific achievement, honors King's more than 40 years dedicated to research in evolution and the genetics of human disease.

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Heart Defect Prediction Technology Could Lead to Earlier, More Informed Treatment

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An experimental model uses genetics-guided biomechanics and patient-derived stem cells to predict what type of inherited heart defect a child will develop, according to authors of a new study in the journal Cell. A multi-institutional team developing the technology – and led by the Cincinnati Children’s Heart Institute – reports May 19 it would let doctors intervene earlier to help patients manage their conditions and help inform future pharmacologic treatment options.

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How Did Cardinals Get Those Bright Red Feathers?

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Male birds with redder feathers win more mates. Researchers at Washington University School of Medicine in St. Louis and colleagues have discovered the gene for red plumage. The gene codes for an enzyme that converts a yellow molecule, which the birds obtain from their diets, into a red one.

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Rhythm Of "Detox" and Feeding Genes in Fruitflies and Mice Coordinated by Neuropeptide

A 24-hour rhythm of cellular detoxification in flies and mammals is coordinated by a neuropeptide that also drives feeding in both organisms. Many detoxification genes are expressed with a circadian rhythm in the mouse liver and in the fruitfly equivalent called the fat body. This work could eventually have implications for chronotherapy -- the study of the timing of when best to take medications.

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A New Amp for 5G Cell Phones, New Ultrasound Method to Analyze Cancer Cells, Synthetic Heart Valves, Discovery of Rules for CRISPR Advance Metabolic Engineering and more in the Engineering News Source

A New Amp for 5G Cell Phones, New Ultrasound Method to Analyze Cancer Cells, Synthetic Heart Valves, Discovery of Rules for CRISPR Advance Metabolic Engineering and more in the Engineering News Source