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Genetics

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Medicine

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Obesity, Epigenetics, DNA, Dna Methylation, Adiposity, Fat Tissue

Risk of Obesity Influenced by Changes in Our Genes

A child’s risk of obesity as they grow up can be influenced by modifications to their DNA prior to birth, a new University of Southampton study has shown.

Medicine

Channels:

Muscle Regeneration, Muscle Repair, Aging, Sarcopenia, Muscle Loss, Duchenne Muscular Dystrophy

New Insights on Triggering Muscle Formation

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A team of scientists led by Lorenzo Puri, M.D., Ph.D., has identified a previously unrecognized step in stem cell-mediated muscle regeneration. The study, published in Genes and Development, helps explain why muscle stem cells lose the ability to generate new muscle as they age and provides insight into accelerated muscle stem cell aging in muscular dystrophy.

Medicine

Science

Channels:

Faseb, American Society For Pharmacology And Experimental Therapeutics, Synthetic Cannabinoids , Genetics, Metabolism, Pharmacology

Genetic Factors May Contribute to Adverse Effects Produced by Synthetic Cannabinoids

Synthetic cannabinoid abuse is a growing problem in the U.S. New discoveries tied to genetic factors that increase a person’s risk for experiencing the most dangerous effects of these drugs could lead to more effective treatments and antidotes.

Medicine

Channels:

Genetics, Postmenopausal Hormone Therapy, Postmenopausal Women, personalized medicine, Fracture, Fracture Risk

Genetics Are Key to Hormone Therapy Lowering Risk of Broken Bones in Older Women

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Women at the highest genetic risk for fracture benefit the most from hormone therapy, according to a first-of-its-kind study led by researchers at the University at Buffalo.

Medicine

Science

Channels:

Faseb, American Society for Nutrition , Nutrition, Genetics, Gene Variation, Diet

Could Genetics Influence What We Like to Eat?

Gene variants could affect food intake and dietary preferences in healthy people, according to a new study. The findings could lead to new strategies that make it easier for people to stick to an optimal diet.

Medicine

Channels:

Genomics, Genetics, Neurofibromatosis

Forecasting the Future of Genomics

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Medicine

Channels:

CRISPR-Cas9, genetic, Eye Disease, Ophthalmology, Retinitis Pigmentosa

Using CRISPR to Reverse Retinitis Pigmentosa and Restore Visual Function

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Using the gene-editing tool CRISPR/Cas9, researchers at University of California San Diego School of Medicine and Shiley Eye Institute at UC San Diego Health, with colleagues in China, have reprogrammed mutated rod photoreceptors to become functioning cone photoreceptors, reversing cellular degeneration and restoring visual function in two mouse models of retinitis pigmentosa.

Science

Channels:

Cohesin, DNA, loop extrusion, Chromatin

Looping the Genome: How Cohesin Does the Trick

DNA molecules in the cells‘ nuclei are neatly folded into loops. This serves to wrap them up tightly, but also to bring distant gene regulatory sequences into close contact. In a paper published this week by NATURE, scientists at the Research Institute of Molecular Pathology (IMP) in Vienna describe how cohesin might do the trick.

Medicine

Channels:

San Diego, Palm Beach, Neuroscience, Neurotransmission, Brain

Closer Look at Brain Circuits Reveals Important Role of Genetics

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Scientists at The Scripps Research Institute (TSRI) in La Jolla have revealed new clues to the wiring of the brain. A team led by Associate Professor Anton Maximov found that neurons in brain regions that store memory can form networks in the absence of synaptic activity.

Medicine

Channels:

Pasricha, Kulkarni, Gastroenterolgy, GUT, Nerve, Genetics

Hopkins Researchers Discover Birth-And-Death Life Cycle of Neurons in the Adult Mouse Gut

Johns Hopkins researchers today published new evidence refuting the long-held scientific belief that the gut nerve cells we’re born with are the same ones we die with.







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