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Study Finds Lead Negatively Impacts Cognitive Functions of Boys More than Girls

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The female hormones estrogen and estradiol may help ward off the effects of lead exposure for young girls, explaining why boys, are shown to suffer more often from the cognitive disabilities linked to lead.

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A reporter's PressPass is required to access this story until the embargo expires on 26-Jan-2015 11:00 AM EST

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Gene May Open Door for Improved Keloid, Scar Treatment

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Researchers at Henry Ford Hospital in Detroit have identified a gene that may offer a better understanding of how keloid scars develop and potentially open the door to improved treatment for the often painful, itchy and tender scars. The study is the first to demonstrate that an altered AHNAK gene may have a significant biological role in keloid development.

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UAB Research Probes Molecular Basis of Rare Genetic Disorder

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The mutation and its functional effects that cause the genetic disorder Singleton-Merten Syndrome (SMS) has been described for the first time, by an international research team. SMS is now recognized as an autoimmune disorder.

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Noisy Data Facilitates Dartmouth Researcher's Investigation of Breast Cancer Gene Expression

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Researchers report on the use of denoising autoencoders (DAs) to effectively extract key biological principles from gene expression data and summarize them into constructed features with convenient properties.

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Scientists Find Gene Vital to Central Nervous System Development

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Scientists have identified a gene that helps regulate how well nerves of the central nervous system are insulated, researchers at Washington University School of Medicine in St. Louis report.

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A reporter's PressPass is required to access this story until the embargo expires on 27-Jan-2015 12:00 PM EST

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New Computation Method Helps Identify Functional DNA

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Striving to unravel and comprehend DNA’s biological significance, Cornell University scientists have created a new computational method that can identify positions in the human genome that play a role in the proper functioning of cells, according to a report published Jan. 19 in the journal Nature Genetics.

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Mutated ATRX Gene Linked to Brain and Pancreatic Neuroendocrine Tumors is Potential Biomarker for Rare Adrenal Tumors Too

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For the first time, researchers at Penn Medicine have found that a mutation in the ATRX gene may serve as a much-needed biomarker for the pheochromocytomas and paragangliomas that become malignant. These rare neuroendocrine tumors are typically benign, but when they go rogue, they become very aggressive.

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Researchers Open ‘Pandora’s Box’ of Potential Cancer Biomarkers

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Researchers at the University of Michigan Comprehensive Cancer Center analyzed the global landscape of a portion of the genome that has not been previously well-explored. This analysis opens the door to discovery of thousands of potential new cancer biomarkers.