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Breast Cancer, cancer proteomics

Rogue Breast Tumor Proteins Point to Potential Drug Therapies

For patients with difficult-to-treat cancers, doctors increasingly rely on genomic testing of tumors to identify errors in the DNA that indicate a tumor can be targeted by existing therapies. But this approach overlooks rogue proteins that may be driving cancer cells and also could be targeted with existing treatments, according to new research led by Washington University School of Medicine in St. Louis.

Medicine

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Pregnancy, Obstetrics, Gestation, Weight, Birth, Mobile App Development , Personalized Medicine, Citizen Science, crowdsource, San Diego, Health, Prenatal

Mobile Technology Shakes Up Pregnancy Research

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Current pregnancy recommendations don’t work for everyone. Researchers at TSRI and STSI aim to change that.

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NIH Grant Will Further Investigation of Breast Tumor Margin Assessment

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The National Institutes of Health has awarded a three-year, $424,081 grant to Magda El-Shenawee, electrical engineering professor, for her work on an intraoperative and rapid method of detecting positive cancer margins during conservative breast cancer surgery, or lumpectomy.

Medicine

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Adverse Childhood Experiences, Menopause, Depression, Womens' Health, Major depressive disorder (MDD) , Penn Medicine, Traumatic Experiences , Psychiatry

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 29-Mar-2017 1:00 PM EDT

Medicine

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Cancer Advocacy, Breast Cancer

FDA Reports Deaths Linked to Breast Implants, Speak with Dr. Williams Gradishar to Learn About Anaplastic Large Cell Lymphoma (BIA-ALCL)

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Medicine

Science

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women & drinking, Older Women, sensitivity to alcohol, Prescr, alcohol education, alcohol screening, Alcohol Treatment

An Increasing Proportion of Women Who Are 60 Years of Age and Older Are Drinking

Most older Americans drink alcohol. Given that this segment of the population is projected to almost double by 2050, reaching 112 million, in the future, there will likely be many more older drinkers in the United States than currently. Importantly, older individuals are more sensitive to alcohol’s effects than their younger counterparts, and are also more likely to take prescription medications that can interact negatively with alcohol, potentially leading to falls and other injuries. This study examined trends in drinking status among U.S. adults 60 years of age and older.

Medicine

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Breast Cancer, nanoparticle degradation, nanoparticle drug delivery, RAN

Nanoparticle Paves the Way for New Triple Negative Breast Cancer Drug

A potential new drug to tackle the highly aggressive ‘triple negative’ breast cancer – and a nanoparticle to deliver it directly into the cancer cells – has been developed by UK researchers.

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Drug Trial for Solid Cancer Tumors, Lynch Syndrome Awareness, Side Effects for Prostate Cancer Treatments, and More in the Cancer News Source

Click here to go directly to the Cancer News Source

Medicine

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Breastfeeding, Child Health, Legislation, Maternal Health, Patient Education

Overcoming Workplace Barriers to Breastfeeding – Review and Recommendations in the Nurse Practitioner

For mothers of new infants, going back to work may pose a number of obstacles to continued breastfeeding. Workplace policies affecting the ability to breastfeed—and the role of nurse practitioners (NPs) in helping to overcome those obstacles—are the topic of a special article in The Nurse Practitioner, published by Wolters Kluwer.

Medicine

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Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering, Breast Cancer, Epigenetic, Epigenetics, José Baselga, Pik3 Ca, PI3K, PI3K inhibitors , ER+, ER+ breast cancer, Science, Research

Researchers Identify First Evidence of Epigenetic Role in Breast Cancer

Researchers from Memorial Sloan Kettering Cancer Center (MSK) have identified, for the first time, an epigenetic mechanism promoting breast cancer. The team found that inhibition of the PI3K pathway leads to activation of ER-dependent transcription through the epigenetic regulator KMT2D. These findings provide a rationale for epigenetic therapy in patients with PIK3CA-mutant, ER-positive breast cancer. While epigenetic factors have been known to play an important role in various cancers such as leukemia and lymphoma, this is the first evidence found in breast cancer.







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