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Science

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Archaeology, Anthropology, hunter-gatherer, Domestication, Jordan Valley, Maasai, mice

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 27-Mar-2017 3:00 PM EDT

Medicine

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Suburban Hospital, Wade Chien, Gene Therapy, Hearing Loss, DEAF, Deafness, Dizziness

Novel Gene Therapy Experiment Offers Hope for People with Certain Hearing Loss and Dizziness Disorder

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In a first-of-its-kind study published in the March 1, 2017 edition of Molecular Therapy, researchers from the National Institute on Deafness and Other Communication Disorders (NIDCD) and Johns Hopkins University School of Medicine showed that gene therapy was able to restore balance and hearing in genetically modified mice that mimic Usher Syndrome, a genetic condition in humans characterized by partial or total hearing loss, dizziness, and vision loss that worsens over time. The hearing loss and dizziness is caused by abnormalities of the inner ear.

Medicine

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Cancer, Prostate Cancer, TMPRSS2:ERG, Peptides, Peptidomimetics, Gene Fusion

A New Approach to Target an ‘Undruggable’ Prostate Cancer Driver

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When small-molecule inhibitors proved elusive, researchers developed a novel strategy: Using large molecule peptides to target a common prostate cancer driver. It may provide a path for developing new therapies against a challenging target.

Medicine

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Duke University Medical Center, Duke University School of Medicine, Duke University, Duke Health, Gender Identity, Transgender, transgender health, transgender medicine, College Student Drinking, College Student Health, College Freshmen, Binge Drinking, Alcohol Abuse, alcohol aggressive behavior, alcohol and violence, Alcohol, Blackouts, Scott Swartzwelder

Transgender College Freshmen Drink More, Experience More Blackouts

A survey of more than 422,000 college freshmen found that students who identified as transgender were more likely than their cisgender peers to experience negative consequences from drinking, including memory blackouts, academic problems and conflicts such as arguments or physical fights.

Medicine

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Seth Margolis, Alzheimer’s, ephexin5 , Brain, Amyloid

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 27-Mar-2017 4:00 PM EDT

Medicine

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Kenneth Tung, Immune System, Lymphatic System, Immune Privilege, Testes, Cancer Vaccine, Cancer, Testicles, Male Reproduction, Reproduction, Sperm, Infertility, Autoimmune, Autoimmune Disorders, Autoimmune Disease, Autoimmune Diseases, UVA, University Of Virginia, Beirne Carter, Beirne Carter Center for Immunology Research, Immunology, Medical Research, UVA Sch

UVA Discovers ANOTHER Immune System Link Science Said Didn't Exist

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UVA researchers have again shown that a part of the body thought to be disconnected from the immune system actually interacts with it, and that discovery helps explain cases of male infertility, certain autoimmune diseases and even the failure of cancer vaccines.

Medicine

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Blindness, Low Vision, Brain, Brain Plasticity

Brain “Rewires” Itself to Enhance Other Senses in Blind People

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The brains of those who are born blind make new connections in the absence of visual information, resulting in enhanced, compensatory abilities such as a heightened sense of hearing, smell and touch, as well as cognitive functions (such as memory and language) according to a new study led by Massachusetts Eye and Ear researchers.

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Penn AIDS Researcher Receives $16.3 Million from NIAID to Hasten HIV Vaccine Development

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Building on earlier work in designing chimeric human-simian immunodeficiency viruses (SHIVs) that serve as a model of HIV infection of humans, George M. Shaw, MD, PhD, a professor of Hematology/Oncology and Microbiology in the Perelman School of Medicine at the University of Pennsylvania, has received $16.3 million over five years from the National Institute of Allergy and Infectious Diseases to develop a long-sought-after HIV vaccine.

Medicine

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Diabetic Retinopathy, Retinopathy Of Prematurity, Premature Babies, Diabetes, Angiogenesis, Lucentis, Eylea, Ranibizumab, aflibercept, Drug Discovery

Study Suggests New Way to Prevent Vision Loss in Diabetics and Premature Babies

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Researchers at Bascom Palmer Eye Institute, part of the University of Miami Miller School of Medicine, have identified a new molecule that induces the formation of abnormal blood vessels in the eyes of diabetic mice. The study, “Secretogranin III as a disease-associated ligand for antiangiogenic therapy of diabetic retinopathy,” which will be published March 22 in The Journal of Experimental Medicine, suggests that inhibiting this molecule may prevent similarly aberrant blood vessels from damaging the vision of not only diabetics, but also premature infants.

Medicine

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Pregnancy, Body Mass Index, Weight Gain, Adolescence, Mother and child

New Study: Pre-Pregnancy BMI Directly Linked to Excess Pregnancy Weight Gain

It’s well known that excessive weight gain during pregnancy can have a lasting negative impact on the health of a mother and her baby. A new University of Michigan-led study finds that for young mothers (women who gave birth between the ages of 15 and 24), pre-pregnancy body mass index, or BMI, and ethnicity might signal a likelihood for obesity later in life.







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