Charles M. Schroeder is the James Economy Professor of Materials Science and Engineering and a professor of chemical and biomolecular engineering at the University of Illinois Urbana-Champaign. He is Co-Chair of the Molecular Science and Engineering Theme and Leader of the AI for Materials Group in the Beckman Institute for Advanced Science and Technology. Professor Schroeder is a faculty member in the Center for Biophysics and Quantitative Biology and holds affiliate status in the Department of Chemistry, the Department of Bioengineering, the Carl R. Woese Institute for Genomic Biology, and the Materials Research Lab. He previously served as Associate Head in the Department of Chemical & Biomolecular Engineering at Illinois.

Professor Schroeder received his B.S. in Chemical Engineering from Carnegie Mellon University in 1999, followed by an M.S. in 2001 and Ph.D. in 2005 in Chemical Engineering from Stanford University. Before joining the University of Illinois in 2008, he was a Jane Coffin Childs Postdoctoral Fellow and a K99/R00 NIH postdoctoral fellow in the Department of Chemistry and Chemical Biology at Harvard University (2004-2007). 

Professor Schroeder is the recipient of several awards, including a Packard Fellowship for Science and Engineering, a Camille Dreyfus Teacher-Scholar Award, an NSF CAREER Award, the Arthur B. Metzner Award from the Society of Rheology, an NIH Pathway to Independence Award (K99/R00), the Dean’s Award for Excellence in Research at Illinois, and the Vision and Spirit Award from the Beckman Institute. Professor Schroeder is a Fellow of the American Association for the Advancement of Science (AAAS Fellow, 2022) and a Fellow of the Society of Rheology (2023).

Research Statement 

The cutting edge of chemical science research lies in the ability to manipulate and control single molecules. The Schroeder group has pioneered a unique and powerful brand of molecular engineering that allows for the precise design and characterization of single molecules, in problems ranging from polymer physics to molecular electronics. Imagine the ability to design and engineer new soft materials with any desired functional properties (e.g., electrical, optical, mechanical) by controlling chemical structure and composition at the molecular level. The Schroeder group aims to achieve this vision by understanding how form and function arise in soft materials given precise control over molecular synthesis, structure, and processing. Current work is defined by four focus areas:

Single polymer dynamics. A major unsolved problem in soft materials and rheology lies in understanding how the collective behavior of individual molecules gives rise to bulk properties in polymeric materials. To address this challenge, the Schroeder group has extended the field of single polymer dynamics to new materials including architecturally complex polymers such as rings and branched polymers. His work provides a molecular-level understanding of non-equilibrium polymer dynamics, bridging the gap between molecular behavior and bulk properties in polymeric liquids and solids. Recent work has focused on fully recyclable synthetic polymers using metastable chemistries.

Vesicle dynamics, biological membranes, microhydrodynamics & Stokes trap. Schroeder's group studies the non-equilibrium conformational dynamics of lipid vesicles and colloidal clusters using a Stokes trap, which is a new method developed by his group that allows for the precise trapping and manipulation of single molecules or particles using automated flow control. Understanding the dynamics of membrane-bound vesicles is critical for developing new and efficient drug delivery vehicles. His recent work has focused on understanding the non-linear deformation of lipid membranes in flow, including phase separation and dynamics of multi-component lipid membranes under tension. 

Automated synthesis for materials discovery. The Schroeder group uses automated synthesis to drive the discovery of new materials for applications including organic electronics and energy storage. A “Lego-like” building block approach is used to synthesize large libraries of chemically diverse, sequence-defined molecules via automated iterative Suzuki coupling (C-C coupling). Automated synthesis is also used in combination with AI-guided, closed-loop discovery methods for new materials, e.g., organic photovoltaics (OPVs) with improved photostability or new electrochromic molecules.

Molecular electronics & bioelectronics. Electron transport in proteins is essential for fundamental life processes in living cells. Understanding these mechanisms at the molecular level remains an open challenge in the field. Recently, the Schroeder group has studied charge transport mechanisms in sequence-defined polymers, redox-active molecules, and supramolecular assemblies using single molecule techniques. His work is focused on bioelectronics by developing new sustainable materials for next-generation electronic devices, including self-assembled protein circuitry and conductive peptide nanowires. 

Department of Materials Science & Engineering profile

Research Group Website

Illinois Experts profile

Title

Cited By

Year

3D manipulation and dynamics of soft materials in 3D flows

3

2023

Enhanced Electron Transport in Nonconjugated Radical Oligomers Occurs by Tunneling

1

2023

Ladder-type conjugated molecules as robust multi-state single-molecule switches

2023

Nanostructure‐Derived Antireflectivity in Leafhopper Brochosomes

2023

Unexpected Slow Relaxation Dynamics in Pure Ring Polymers Arise from Intermolecular Interactions

2

2023

Dynamics of meniscus-bound particle clusters in extensional flow

2023

Unique Stretching Dynamics of Single Ring Polymers in 3-Dimensional Flows

2023

Understanding Single-Molecule Charge Transport in Multi-state, Ladder-type Conjugated Molecules

2023

Effect of salt and crosslinking density on viscoelasticity and conductivity of vitrimers

2023

Single Molecule Polymer Physics in 3D Flows

2023

Single Polymer Dynamics of Ring-Linear Blends and Entangled Solutions

2023

Exploring the Role of Brochosome Variation on the Wettability of LeafhopperWings (Hemiptera: Cicadellidae)

2023

Open Macromolecular Genome: Generative Design of Synthetically Accessible Polymers

2

2023

Electron Tomography and Machine Learning for Understanding the Highly Ordered Structure of Leafhopper Brochosomes

2

2022

Autonomous Materials Discovery for Organic Photovoltaics

2022

Self-Assembly of Repetitive Segment and Random Segment Polymer Architectures

1

2022

Hierarchical Control and Characterization of Synthetic and Biopolymer Materials

2022

Automated Measurement of Electrogenerated Redox Species Degradation Using Multiplexed Interdigitated Electrode Arrays

5

2022

Closed-loop optimization of general reaction conditions for heteroaryl Suzuki-Miyaura coupling

30

2022

Understanding Supramolecular Assembly of Supercharged Proteins

1

2022

Lightening the load: Researchers develop autonomous electrochemistry robot

Beckman researchers developed a cost-friendly, customizable, electrochemistry robot called the Electrolab to perform autonomous experiments in the laboratory. The Electrolab will be used to explore next-generation energy storage materials and chemical reactions that promote alternative and sustainable energy.
06-Nov-2023 01:05:32 PM EST

Mix it, test it, create it: NSF funds automated polymer research instrument at the Beckman Institute

University of Illinois researchers received NSF funding to acquire a fully automated polymer analysis instrument to be housed at the Beckman Institute.
14-Sep-2023 12:05:15 PM EDT

“When you have these large datasets, artificial intelligence helps to tease out nonobvious correlations — the ones that appear to be subtle but are actually very important."

- Mix it, test it, create it: NSF funds automated polymer research instrument at the Beckman Institute

“Our work provides a significant step forward towards the development of functional molecular electronic devices."

- Researchers demonstrate single-molecule electronic "switch" using ladder-like molecules

"Prioritize the search for fundamental knowledge,” he said. “Prioritize the training and mentoring of students and young scientists. Prioritize building teams and developing new ideas rather than seeking personal or singular recognition on shared projects. Prioritize the pursuit of excellence at all levels — including relationship building — while seeking to move the field forward with new ideas.”

- Charles Schroeder wins Beckman’s Vision and Spirit Award

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