Investigators at Children’s Hospital Los Angeles are providing new hope for babies with short bowel syndrome (SBS) by developing a novel model of SBS in zebrafish, described in a paper published online on June 18 by the American Journal of Physiology-Gastrointestinal and Liver Physiology.
In a finding that furthers the understanding of human immunodeficiency virus (HIV), researchers from Children’s Hospital Los Angeles discovered two locations where a single difference in HIV’s genetic code altered the way the virus infected the cell, thereby influencing the progression of the disease.
Cedars-Sinai's medical tip sheet for June includes story ideas about how memories and memory-based decisions are processed in the brain, getting a second opinion via a tele-consult, and more.
The UCLA Medical Group has again earned the highest rating possible in an annual survey conducted by CAPG, an association representing physician organizations in 38 states, Washington, D.C., and Puerto Rico. UCLA earned five stars in the report, which assesses health care systems’ tools for delivering better patient experience and better population health, as well as overall affordability.
Researchers at Children’s Hospital Los Angeles have demonstrated that adolescents and young adults with congenital adrenal hyperplasia (CAH) have significantly increased amounts of abdominal fat tissue, placing them at greater risk for harmful conditions linked to obesity, including cardiovascular disease (CVD).
On Friday, May 22, an 18-member team of physicians and nurses from Children's Hospital Los Angeles (CHLA) and Keck Medicine of the University of Southern California (USC) led an international collaboration to separate a pair of six-month-old conjoined Haitian twins, the first such operation ever performed on Haitian soil. James Stein, associate chief of surgery at Children's Hospital, was lead surgeon during the rare medical procedure.
U.S. News and World Report has recognized Mattel Children’s Hospital UCLA for excellence in nine specialties in the 2015-16 Best Children’s Hospitals rankings.
Using functional magnetic resonance imaging, a team of UCLA researchers has shown for the first time that children with autism spectrum disorder (ASD) who are overly sensitive to sensory stimuli have brains that react differently than those with the disorder who don’t respond so severely to noises, visual stimulation and physical contact.
On Friday, May 22, an 18-member team of physicians and nurses from Children's Hospital Los Angeles (CHLA) and Keck Medicine of the University of Southern California (USC) led an international collaboration to separate a pair of six-month-old conjoined Haitian twins, the first such operation ever performed on Haitian soil.
Ranked No. 1 in California and among the top 10 nationally, CHLA is once again named to the prestigious Honor Roll in the U.S. News & World Report survey of the nation’s best children’s hospitals.
The witness on the stand says he saw the accused at the scene of the crime. Is he sure? How sure? The jury’s verdict could hinge on that level of certainty. Many decisions we make every day are influenced by our memories and the confidence we have in them. But very little is known about how we decide whether we can trust a memory or not. Cedars-Sinai researchers have identified a unique set of neurons in the medial temporal lobe, an area of the brain where memories and memory-based decisions are processed. They show that the activity of these neurons is indicative of the confidence by which a memory will be retrieved.
Wounded Warrior Project has approved a $15.7 million grant over three years for UCLA Health to expand its Operation Mend program to create a new, intensive structured treatment program for service members who have suffered mild traumatic brain injury and post-traumatic stress disorder.
Children’s Hospital Los Angeles (CHLA) opened the doors of its new outpatient care center in Encino today. The pediatric medical facility, Children’s Hospital Los Angeles – Encino, will be staffed by physicians who are Board-certified in pediatric specialties and subspecialties, including hematology-oncology, nephrology, neurology, orthopaedics, pediatric surgery and urology.
A portable, finger-probe device successfully measured liver function in brain dead adult organ donors, a finding that could change the way organs are assessed and save thousands of dollars per transplant, a UCLA study has found.
Studying zebrafish, investigators at The Saban Research Institute and the Heart Institute of Children’s Hospital Los Angeles discovered a new source for cells that can develop into coronary vessels and have identified the signaling protein, a chemokine called CXCL12, which guides this process.
The May Medical Tip Sheet from Cedars-Sinai includes story ideas related to nanotechnology and a "virtual biopsy," a $4.9 million grant from the California Institute for Regenerative Medicine to study retinitis pigmentosa, definitive tests for IBS, a preventive for 80 percent of cervical cancers and more. To pursue any of these story ideas, please contact the individual listed for each.
Biomedical researchers at Cedars-Sinai have invented a tiny drug-delivery system that can identify cancer cell types in the brain through “virtual biopsies” and then attack the molecular structure of the disease.
Researchers and public health officials have looked for ways to better understand the health concerns of transgender populations, so social "big data" technologies like Twitter offer an untapped rich source of information that they can use for the benefit of these communities
Can the use of a virtual drivers programmed to resemble humans increase the level of trust and acceptance in smart cars?
Parents of patients treated at Children’s Hospital Los Angeles can download a free app called ImageInbox on their smartphones, which allows them to receive imaging files or to request the files be sent directly to another caregiver. CHLA is the first clinical site to offer the app, which is now available for free to any patient.
Researchers found that the presence of a few remaining leukemia cells, called minimal residual disease (MRD), at the end of induction chemotherapy was not predictive of risk or outcome in children with T-cell acute lymphoblastic leukemia (ALL). This opens the possibility for patients with T-cell ALL who have MRD to achieve complete remission without undergoing intensified cancer treatments and their associated toxicities.
Millions of people afflicted by irritable bowel syndrome can now be diagnosed quickly and accurately with two simple blood tests developed by a Cedars-Sinai gastroenterologist.
Researchers have made an important step toward finding a target in the fight against drug-resistant neuroblastoma (NBL), the most common solid malignancy found, outside of the skull, in children.
The newest human papillomavirus vaccine, 9-Valent, can potentially prevent 80 percent of cervical cancers in the United States if given to all 11- or 12-year-old children before they are exposed to the virus.
Mental health. It’s a term we most often associate with adults and balancing high-stress jobs with an enjoyable lifestyle. But what exactly does “mental health” mean for infants and families? We talked to Marian E. Williams, PhD, director of the Stein Tikun Olam Infant-Family Mental Health Initiative at Children’s Hospital Los Angeles to learn more about this often “taboo” topic.
Few doctors are prescribing a low-cost drug that has been proven effective in preventing the onset of diabetes. New research finds that only 3.7 percent of U.S. adults with pre-diabetes were prescribed metformin during a recent three-year period.
Now, parents share their arduous and “circuitous” journey to get referrals for pediatric epilepsy surgery once their child’s disease stops responding to anti-seizure medications. The UCLA study sheds light on the difficulties parents face obtaining specialty and sub-specialty care for their children during an already stressful time.
An international team of scientists led by a Cedars-Sinai researcher has identified a new genetic mutation that appears to protect people from developing Type 2 diabetes.
Children with hemophilia A require three to four infusions each week to prevent bleeding episodes, chronic pain and joint damage. A new, extended therapy combines recombinant factor VIII with a fusion protein that allows the molecule to remain in the circulation longer – translating into a need for less frequent treatment.
Here at Children’s Hospital Los Angeles, transgender issues are not new. Our Division of Adolescent and Young Adult Medicine has been supporting the health of transgender youth for nearly 20 years. While many are becoming more familiar with the subject now, there is still great opportunity to advance understanding in the community. In this post, Johanna Olson, MD, medical director of the Center for Transyouth Health and Development at CHLA, gives answers to questions that many are asking, including what the term ‘transgender’ means, what the transition process includes, and services that are available for transyouth.
Johanna Olson, MD, is a pediatrician specializing in adolescent medicine at Children’s Hospital Los Angeles where she directs the Center for Transyouth Health and Development. In an effort to increase knowledge about the transgender experience, Olson frequently speaks to media on the topic.
The April tip sheet from Cedars-Sinai includes story idea pertaining to heart transplantation, macular degeneration, and sudden cardiac arrest in athletes. To pursue any of these story ideas, please contact the individual listed.
Women who experience extreme morning sickness during pregnancy are three times more likely to have children with developmental issues, including attention disorders and language and speech delays, than woman who have normal nausea and vomiting, a UCLA study has found.
A UCLA-led study on improving stroke care was selected by the Clinical Research Forum (CRF) as one of the 10 most outstanding research papers written by teams from across the nation in 2014.
Only 9 percent of U.S. academic medical practices have procedures for connecting patients to LGBT-competent physicians, and only 4 percent had policies for identifying those physicians. In addition, only 15 percent had lists of LGBT-competent physicians.
Children’s Hospital Los Angeles (CHLA) announced Thursday the grand opening and dedication of the Margie and Robert E. Petersen Foundation Rehabilitation Center honoring the couple’s two late sons, Bobby and Richie Petersen, who died in a 1975 plane crash. Late last month patients and staff moved in to the new 22,000-square-foot, safari-themed facility.
77 percent of California primary care and specialty physicians understand the basics of the Patient Protection and Affordable Care Act and 59 percent support it. Also, 525 doctors surveyed believe ACA will steer the country’s health care in the right direction.
An injection of stem cells into the eye may soon slow or reverse the effects of early-stage age-related macular degeneration, according to new research from scientists at Cedars-Sinai. Currently, there is no treatment that slows the progression of the disease, which is the leading cause of vision loss in people over 65.
Rachel Koszegi is on a mission to fight cancer, and she’s not alone. The 33-year-old mother who has tested positive for the BRCA2 cancer gene is one of 12 people in her family over three generations linked to the gene or diagnosed with cancer. Now she is using her family’s genetic history to contribute to cancer research, prevention and treatment – with the aim of improving the quality of life for those facing hereditary risk.
The Cedars-Sinai Heart Institute completed 120 adult heart transplants and two adult heart-lung transplants in 2014, setting a new national standard for the most adult heart transplants performed in a single year.
EMBARGOED HEART RESEARCH: Middle-aged athletes are at low risk for having a sudden cardiac arrest while playing sports, and those who do have a greater chance of surviving the usually-fatal condition, shows a new Cedars-Sinai Heart Institute study.
A new UCLA study takes another step toward the early understanding of a degenerative brain condition called chronic traumatic encephalopathy, or CTE, which affects athletes in contact sports who are exposed to repetitive brain injuries. Using a new imaging tool, researchers found a strikingly similar pattern of abnormal protein deposits in the brains of retired NFL players who suffered from concussions.
Research suggests that HIV induces age-associated changes to the DNA, which in turn lead to earlier onset of age-related illnesses such as some cancers, renal and kidney disease, frailty, osteoporosis and neurocognitive diseases by more than 14 years.
Michael Neely, MD, a pediatric infectious diseases specialist at Children’s Hospital Los Angeles, helps explain the facts about measles, and how parents can prevent further outbreak. MD, a pediatric infectious diseases specialist at Children’s Hospital Los Angeles, helps explain the facts about measles, how parents can prevent further outbreak, and what CHLA can do to help prevent infection and to treat those who have already been infected.
Leaders from Children’s Hospital Los Angeles (CHLA) and the National Center for Maternal and Child Health (NCMCH), Mongolia’s flagship pediatric medical facility, marked 20 years of institutional collaboration Tuesday with a special “telemedicine” program and celebration honoring past accomplishments and outlining future efforts to better the health care of Mongolian children.
Religion Dispatches hires award-winning journalist Cathleen Falsani as Senior Editor for new project
a team of UCLA researchers has shown for the first time in a large cohort of patients that electroconvulsive therapy (ECT), sometimes referred to as shock treatment, change certain areas of the brain that play a role in how people feel, learn and respond to positive and negative environmental factors.
The March tip sheet from Cedars-Sinai includes information on exercise and sexual function, gut bacteria and weight loss surgery, students learning about exercise and brain health, an international nanomedicine conference and more.
Characterizing associations between socioeconomic factors and children’s brain development, a team of investigators reports correlative links between family income and brain structure. Relationships between the brain and family income were strongest in the lowest end of the economic range – suggesting that interventional policies aimed at these children may have the largest societal impact.
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