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Boosting a protective protein to stabilize blood vessels that are weakened by malaria showed improved survival, beyond that of antimalarial drugs alone in pre-clinical research. Toronto General Research Institute (TGRI) and the Sandra Rotman Centre for Global Health, University of Toronto and University Health Network (UHN) researchers describe in Science Translational Medicine how their approach bolsters the body’s own capabilities to protect itself against cerebral malaria, rather than solely targeting the malaria parasites in the blood.

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Heart disease patients enrolled in a clinical trial - designed to test whether a stronger dose of the influenza vaccine can prevent death or hospitalization due to a heart attack, heart failure, stroke or pneumonia - have begun receiving their first flu shots in Toronto and Boston.

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Patients, physicians and attendees will throw their lines in for an important catch today at the Caledon Mountain Trout Club during the first ‘Cast & Blast’ event to support research into the often fatal heart disorder called arrythmogenic right ventricular cardiomyopathy (ARVC). Spearheaded by Heather Cartweight, an ARVC patient, and her family, the event directly supports the Heather Cartwright Inherited Cardiomyopathy and Arrythmia Project at the Peter Munk Cardiac Centre (PMCC), University Health Network (UHN).

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The Rexall OneWalk to Conquer Cancer announced 3,555 participants raised $6.5 million for Princess Margaret Cancer Centre as the event commenced on Saturday.

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Professor Brian Hodges is awarded the 2016 Karolinska Institutet Prize for Research in Medical Education. His research has led to changes in educational practice, both scientific and practical, in the training of health professionals around the world. As an example, simulations and assessment of patients' mental health and students' communication skills are now included in medical examinations in many countries.

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Breast cancer researchers have discovered that mutations found outside of genes that accumulate in estrogen receptor positive breast tumours throughout their development act as dominant culprits driving the disease.

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Researchers at the Peter Munk Cardiac Centre, with expertise running large clinical trials, and at Mayo Clinic, are leading the Tailored Antiplatelet Therapy to Lessen Outcomes after Percutaneous Coronary Intervention (TAILOR-PCI) study. This study has received $7 million in additional funding from the National Heart, Lung and Blood Institute (NHLBI) of the National Institutes of Health (NIH).

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Prostate cancer researchers studying genetic variations have pinpointed 45 genes associated with disease development and progression.

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The Princess Margaret Cancer Foundation is thrilled to announce the Ontario Hockey League Alumni Association (OHLAA) will be supporting this year’s Scotiabank Road Hockey to Conquer Cancer event.

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Researchers from the University Health Network’s Department of Anesthesia and Pain Management and the Institute for Clinical Evaluative Sciences (ICES) have determined that patients who have not had an opioid prescription within a year prior to their procedure are at low risk of developing persistent opioid use after major surgery.

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Krembil Research Institute researchers have discovered a pair of tissue biomarkers that directly contribute to the harmful joint degeneration associated with spine osteoarthritis.

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Leading scientists from over 20 countries will present their latest findings on 22q, a syndrome caused by a small deletion on the 22nd chromosome, at the 10th Biennial International 22q11.2 Conference beginning today in Sirmione, Italy. Newborn screening, recent studies of non-invasive prenatal testing, best practice management and prevention methods across the lifespan of a patient with 22q, will be discussed during the two-day meeting.

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New findings published today by a team of researchers led by Dr. Andres Lozano at the Krembil Neuroscience Centre (KNC) of Toronto Western Hospital (TWH) have provided further insight into the effects of Deep Brain Stimulation (DBS) in the treatment of Alzheimer’s disease.

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Dr. Gang Zheng and a team of biomedical researchers have discovered a “smart” organic, biodegradable nanoparticle that uses heat and light in a controlled manner to potentially target and ablate tumours with greater precision.

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International stem cell scientists, co-led in Canada by Dr. John Dick and in the Netherlands by Dr. Gerald de Haan, have discovered the switch to harness the power of cord blood and potentially increase the supply of stem cells for cancer patients needing transplantation therapy to fight their disease.

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Costs of patients who develop chronic post-surgical pain could range from $2.5 million to $4.1 million a year, in one Ontario hospital alone, according to a study in Pain Management.

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Prostate cancer researchers have discovered biomarkers using non-invasive liquid biopsies to identify aggressive disease before surgery.

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Toronto Rehab researchers have discovered a new approach for determining which patient populations benefit most from cardiac rehabilitation.

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Handheld, mobile phone-based microscopes can be used in developing countries after minimal training of community laboratory technicians to diagnose intestinal parasites quickly and accurately.

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The Princess Margaret Cancer Foundation is proud to announce that over $1.2 million has been raised, bringing the three year total raised to $3.4 million.

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Dr. Douglas Lee, an internationally-known Peter Munk Cardiac Centre cardiologist and scientist, has been selected as first-ever chair for the Ted Rogers Centre for Heart Research, a Toronto collaboration aiming to transform the care of children and adults with heart failure.

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Scotiabank Road Hockey to Conquer Cancer is excited to announce that the Hanson Brothers will pick up their sticks and put on the foil at Woodbine Racetrack on Saturday October, 1st, 2016 – all in the name of conquering cancer.

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Online educational tool targets the most rapidly rising cardiovascular disease in Canada

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Physician thought leaders specializing in hypertrophic cardiomyopathy (HCM), a potentially deadly cardiac condition caused by an abnormal thickening of the heart muscle, will gather in Toronto on May 21 and 22nd, for the inaugural HCM Summit Toronto 2016.

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Cancer researchers have identified a marker that shows up in a blood test that determines which patients with colorectal cancer that has spread would benefit from receiving the drug cetuximab.

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The Princess Margaret Cancer Foundation is thrilled to announce Scotiabank as the new title sponsor for the Scotiabank Road Hockey to Conquer Cancer annual tournament for the next five years.

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Ted Rogers Centre for Heart Research blends clinical care, genetics and regenerative medicine in inaugural event dedicated to ending an epidemic

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A new Canadian study focusing on caregiver outcomes of critically ill patients reveals that caregivers of intensive care unit (ICU) survivors, who have received mechanical ventilation for a minimum of seven days, are at a high risk of developing clinical depression persisting up to one year after discharge.

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Breast cancer patients undergoing treatment with trastuzumab-containing regimens should be monitored for heart damage regardless of age. This is among the findings of a new study from the Peter Munk Cardiac Centre, the Institute for Clinical Evaluative Sciences (ICES) and the Ted Rogers Centre for Heart Research, University Health Network (UHN).

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An ingrained stigma attached to the label “palliative care” among cancer patients, families and healthcare providers impedes earlier access to supportive care that improves quality of life, shows new research from Princess Margaret Cancer Centre.

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Dr. Mansoor Husain named first executive director of Ted Rogers Centre for Heart Research

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Researchers at Princess Margaret Cancer Centre have confirmed in a screening effectiveness study that early screening with MRIs can reduce breast cancer mortality for female survivors of childhood Hodgkin’s lymphoma (HL) who received chest radiation.

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The Krembil Neuroscience Centre's Canadian Concussion Centre (CCC) announces that the analysis of the brain of former NHL player Todd Ewen did not show signs of chronic traumatic encephalopathy (CTE) – a neurodegenerative brain disorder that has been linked to multiple concussions.

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Potentially deadly tumours or abnormal growths found in the heart or heart valves can either originate in the heart or spread to the heart from cancer found elsewhere. While considered rare, cardiac tumours remain prevalent and can be difficult to treat depending on their size and location. They also require precise medical expertise ― not widely available ― to properly treat patients. With this specific knowledge and skill among its internationally-renown staff, the Peter Munk Cardiac Centre along with the University of Toronto, are jointly hosting the first Toronto Cardiac Tumour Conference, which will take place on January 21, 2016.

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In a Canadian first, a multi-disciplinary team at the University Health Network has successfully completed the country’s first transplant of the upper limb.

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A quick screening method has been used for the first time in a standard open laboratory to identify and test promising anti-Ebola drugs. This approach increases the possibility of finding new therapies faster.

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Researchers have discovered how to diagnose Alzheimer’s disease with more than 82 per cent accuracy by evaluating the interplay between four linguistic factors; and developing automated technology to detect these impairments.

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Scientists at Princess Margaret Cancer Centre have discovered that blocking the master regulator of bone renewal stops osteosarcoma – the most common primary bone cancer in children and teens, and the malignant disease that was fatal for Canadian icon Terry Fox.

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Researchers from the University of Toronto have found that a specific cell type plays a key role in maintaining healthy arteries after inflammation. It’s a discovery that could provide treatment options for cardiovascular disease — one of the leading causes of death in Canada.

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Toronto General Hospital performs world-first triple transplant combination of double lung, liver and pancreas organs simultaneously

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Research by Dr. Michael Fehlings, Neurosurgeon, Krembil Neuroscience Centre, has shown that the neuroprotectant drug, riluzole, combined with decompression surgery results in better long-term improvements in forelimb function in cervical spondylotic myelopathy (CSM) animal models than in those only treated with surgery.

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Researchers at the Toronto Rehabilitation Institute (Toronto Rehab) are examining how falls can be prevented in people’s homes, and out in the community while also encouraging safe activity.

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Today marks the one-year anniversary of the biggest private donation in Canadian health-care history that enabled a unique collaboration between three world-renowned institutions creating the Ted Rogers Centre for Heart Research.

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Researchers at the Toronto Western Hospital (TWH) Liver Clinic have found that a simple drug regimen delivered over 1​2 weeks achieved sustained eradication of several genotypes of the hepatitis C virus (HCV) in 99 per cent of the trial's patients.

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Bypass patients who are older, female and/or from lower-income neighbourhoods are more likely to face delays in beginning cardiac rehabilitation (CR), making them less likely to complete CR, which can lead to a higher mortality risk, suggests a new study.

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Stem-cell scientists led by Dr. John Dick have discovered a completely new view of how human blood is made, upending conventional dogma from the 1960s.

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The Canadian Association of Marketing Professionals (CAMP) awarded The Princess Margaret Cancer Foundation its Marketer of the Year Award in the Non-Profit Category for the innovative #NoHairSelfie Campaign.

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Researchers in the Epilepsy Genetics Program of the Krembil Neuroscience Centre have discovered a gene mutation that increases the risk of sudden unexpected death in epilepsy (SUDEP) in patients with mild forms of the disease.

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(September 26; Toronto) There's an unmistakable sound -- the 'thwack' of a hockey stick striking a road hockey ball on pavement -- that has been readily recognizable since we were children. And on Saturday, September 26, that sound filled the parking lots of Woodbine Racetrack, mixed with the excitement a major event as THE Road Hockey to Conquer Cancer took place.

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Like many Canadians, thousands of hockey players will be waking up early on Saturday, September 26 to play the game we love. Only this time, they will be using their SHER-WOOD to help conquer cancer at the 5th annual Road Hockey to Conquer Cancer.