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Boosting a protective protein to stabilize blood vessels that are weakened by malaria showed improved survival, beyond that of antimalarial drugs alone in pre-clinical research. Toronto General Research Institute (TGRI) and the Sandra Rotman Centre for Global Health, University of Toronto and University Health Network (UHN) researchers describe in Science Translational Medicine how their approach bolsters the body’s own capabilities to protect itself against cerebral malaria, rather than solely targeting the malaria parasites in the blood.

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Heart disease patients enrolled in a clinical trial - designed to test whether a stronger dose of the influenza vaccine can prevent death or hospitalization due to a heart attack, heart failure, stroke or pneumonia - have begun receiving their first flu shots in Toronto and Boston.

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Patients, physicians and attendees will throw their lines in for an important catch today at the Caledon Mountain Trout Club during the first ‘Cast & Blast’ event to support research into the often fatal heart disorder called arrythmogenic right ventricular cardiomyopathy (ARVC). Spearheaded by Heather Cartweight, an ARVC patient, and her family, the event directly supports the Heather Cartwright Inherited Cardiomyopathy and Arrythmia Project at the Peter Munk Cardiac Centre (PMCC), University Health Network (UHN).

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The Rexall OneWalk to Conquer Cancer announced 3,555 participants raised $6.5 million for Princess Margaret Cancer Centre as the event commenced on Saturday.

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Professor Brian Hodges is awarded the 2016 Karolinska Institutet Prize for Research in Medical Education. His research has led to changes in educational practice, both scientific and practical, in the training of health professionals around the world. As an example, simulations and assessment of patients' mental health and students' communication skills are now included in medical examinations in many countries.

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Breast cancer researchers have discovered that mutations found outside of genes that accumulate in estrogen receptor positive breast tumours throughout their development act as dominant culprits driving the disease.

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Researchers at the Peter Munk Cardiac Centre, with expertise running large clinical trials, and at Mayo Clinic, are leading the Tailored Antiplatelet Therapy to Lessen Outcomes after Percutaneous Coronary Intervention (TAILOR-PCI) study. This study has received $7 million in additional funding from the National Heart, Lung and Blood Institute (NHLBI) of the National Institutes of Health (NIH).

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Prostate cancer researchers studying genetic variations have pinpointed 45 genes associated with disease development and progression.

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The Princess Margaret Cancer Foundation is thrilled to announce the Ontario Hockey League Alumni Association (OHLAA) will be supporting this year’s Scotiabank Road Hockey to Conquer Cancer event.

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Researchers from the University Health Network’s Department of Anesthesia and Pain Management and the Institute for Clinical Evaluative Sciences (ICES) have determined that patients who have not had an opioid prescription within a year prior to their procedure are at low risk of developing persistent opioid use after major surgery.

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Krembil Research Institute researchers have discovered a pair of tissue biomarkers that directly contribute to the harmful joint degeneration associated with spine osteoarthritis.

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Leading scientists from over 20 countries will present their latest findings on 22q, a syndrome caused by a small deletion on the 22nd chromosome, at the 10th Biennial International 22q11.2 Conference beginning today in Sirmione, Italy. Newborn screening, recent studies of non-invasive prenatal testing, best practice management and prevention methods across the lifespan of a patient with 22q, will be discussed during the two-day meeting.

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New findings published today by a team of researchers led by Dr. Andres Lozano at the Krembil Neuroscience Centre (KNC) of Toronto Western Hospital (TWH) have provided further insight into the effects of Deep Brain Stimulation (DBS) in the treatment of Alzheimer’s disease.

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Dr. Gang Zheng and a team of biomedical researchers have discovered a “smart” organic, biodegradable nanoparticle that uses heat and light in a controlled manner to potentially target and ablate tumours with greater precision.

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International stem cell scientists, co-led in Canada by Dr. John Dick and in the Netherlands by Dr. Gerald de Haan, have discovered the switch to harness the power of cord blood and potentially increase the supply of stem cells for cancer patients needing transplantation therapy to fight their disease.

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Costs of patients who develop chronic post-surgical pain could range from $2.5 million to $4.1 million a year, in one Ontario hospital alone, according to a study in Pain Management.

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Prostate cancer researchers have discovered biomarkers using non-invasive liquid biopsies to identify aggressive disease before surgery.

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Toronto Rehab researchers have discovered a new approach for determining which patient populations benefit most from cardiac rehabilitation.

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Handheld, mobile phone-based microscopes can be used in developing countries after minimal training of community laboratory technicians to diagnose intestinal parasites quickly and accurately.

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The Princess Margaret Cancer Foundation is proud to announce that over $1.2 million has been raised, bringing the three year total raised to $3.4 million.

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Dr. Douglas Lee, an internationally-known Peter Munk Cardiac Centre cardiologist and scientist, has been selected as first-ever chair for the Ted Rogers Centre for Heart Research, a Toronto collaboration aiming to transform the care of children and adults with heart failure.

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Scotiabank Road Hockey to Conquer Cancer is excited to announce that the Hanson Brothers will pick up their sticks and put on the foil at Woodbine Racetrack on Saturday October, 1st, 2016 – all in the name of conquering cancer.

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Online educational tool targets the most rapidly rising cardiovascular disease in Canada

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Physician thought leaders specializing in hypertrophic cardiomyopathy (HCM), a potentially deadly cardiac condition caused by an abnormal thickening of the heart muscle, will gather in Toronto on May 21 and 22nd, for the inaugural HCM Summit Toronto 2016.

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Cancer researchers have identified a marker that shows up in a blood test that determines which patients with colorectal cancer that has spread would benefit from receiving the drug cetuximab.

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The Princess Margaret Cancer Foundation is thrilled to announce Scotiabank as the new title sponsor for the Scotiabank Road Hockey to Conquer Cancer annual tournament for the next five years.

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Ted Rogers Centre for Heart Research blends clinical care, genetics and regenerative medicine in inaugural event dedicated to ending an epidemic

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A new Canadian study focusing on caregiver outcomes of critically ill patients reveals that caregivers of intensive care unit (ICU) survivors, who have received mechanical ventilation for a minimum of seven days, are at a high risk of developing clinical depression persisting up to one year after discharge.

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Breast cancer patients undergoing treatment with trastuzumab-containing regimens should be monitored for heart damage regardless of age. This is among the findings of a new study from the Peter Munk Cardiac Centre, the Institute for Clinical Evaluative Sciences (ICES) and the Ted Rogers Centre for Heart Research, University Health Network (UHN).

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An ingrained stigma attached to the label “palliative care” among cancer patients, families and healthcare providers impedes earlier access to supportive care that improves quality of life, shows new research from Princess Margaret Cancer Centre.