EMBARGOED FOR RELEASE UNTIL 5 P.M., EDT, SATURDAY, MAY 31, 1997
June 1, 1997, Tip Sheet
Annals of Internal Medicine is published by the American College of Physicians (ACP), more than 100,000 physicians trained in internal medicine. The following highlights are not intended to substitute for articles as sources of information. For a copy of an article, call 1-800-523-1546, ext. 2656 or 215-351-2656. * * *
One Patient's Impact on Clinical Trial Research and Informed Consent
An essay by a cancer patient who participated in several phase I clinical trials before his death provides insight into issues relating to informed consent in clinical research, and an understanding of persons with incurable diseases who choose to become involved in investigational therapies. Included in the perspective is a commentary on the essay and the concerns that it raises. The patient's essay encouraged a research project designed to examine the motivation, understanding, and rights of the participants of phase I cancer trials. (Article, p. 892.) Deficiencies in the current process of clinical trials include accrual, the ability of patients and physicians to make autonomous decisions, and arguments from patients and advocacy groups in favor of adequate reimbursement, the commentary shows.
* * * A History of Discrimination in Health Care
A historical analysis investigates strategies used by lawyers, physicians, dentists and patients in elevating the level of health care for black persons in the 1960s. (Article, p. 898.) The author specifically examines the landmark case of Simkins v Moses H. Cone Memorial Hospital, which was a critical historical event in the elimination of segregated health care.
An accompanying editorial describes the struggle to achieve racial equality in health care, and looks at how discrimination affects health care today. (Editorial, p. 910.) Intensity of care and provision of services have been found to vary with race and economic status, the author states. Physicians should act as the informed, committed, and insistent conscience in the quest for access, equality and medical justice.
* * * The Role of Hypertriglyceridemia in Cardiovascular Disease
An editorial examines the role of hypertriglyceridemia (the other major circulating blood fat besides cholesterol) in the development of atherosclerotic cardiovascular disease and offers suggestions for evaluating and treating patients with elevated triglyceride levels. (Editorial, p. 912.)
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